Chronic Obstructive Pulmonary Disease
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CLINICAL_TRIALS trial_result · 2011-08-18Clinical Trial Update: Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease [Phase 3]
This Phase 3 trial evaluated the efficacy and safety of combining indacaterol with tiotropium versus tiotropium alone in chronic obstructive…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Efficacy and Safety of Indacaterol in Adults (40 Years and Above) With Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]
A Phase 3 trial evaluated the efficacy and safety of indacaterol in adults 40 and older with chronic obstructive pulmonary disease. The resu…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Study to Determine the Onset of Action of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]
Phase 3 trial evaluating the onset of action of indacaterol in patients with moderate-to-severe chronic obstructive pulmonary disease; resul…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Dose Ranging Study of Indacaterol in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD) [Phase 2]
A Phase 2 dose-ranging study of indacaterol in Japanese patients with chronic obstructive pulmonary disease has completed, with results post…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: The Effect of Indacaterol on Exercise Endurance in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease [Phase 3]
Phase 3 clinical trial assessing indacaterol on exercise endurance in patients with moderate to severe chronic obstructive pulmonary disease…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Confirmatory Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]
Phase 3 confirmatory trial of indacaterol for chronic obstructive pulmonary disease completed; results posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Study of Indacaterol Dosed in the Evening in Patients With Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]
A Phase 3 study evaluating evening dosing of indacaterol in patients with chronic obstructive pulmonary disease has completed and results we…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: A Crossover Study to Determine the Effect on Lung Function of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Using Tiotropium as an Active Control [Phase 3]
A Phase 3 crossover trial compared indacaterol to tiotropium as an active control to evaluate lung function in patients with moderate to sev…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Disturbances in BCAA Metabolism and the Effects of Feeding and Exercise in COPD [NA]
A completed clinical trial investigating disturbances in branched-chain amino acid metabolism and the effects of feeding and exercise on ind…
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CLINICAL_TRIALS trial_result · 2011-08-09Clinical Trial Update: Impact of Morning Symptoms in Clinical Control of Chronic Obstructive Pulmonary Disease (COPD)
A completed AstraZeneca-sponsored clinical trial evaluating how morning symptoms affect clinical control of chronic obstructive pulmonary di…
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: The Study Will Evaluate the Effect of AZD9164 in Patients With Chronic Obstructive Pulmonary Disease [Phase 2]
This clinical trial update reports the completion of a Phase 2 study evaluating AZD9164 in patients with Chronic Obstructive Pulmonary Disea…
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CLINICAL_TRIALS research · 2011-08-05Clinical Trial Update: Treatment With AKL1 in Obstructive Airways Disease (The TAKL Study) [Phase 2, Phase 3]
A phase 2/3 clinical trial update for AKL1 in obstructive airway diseases, including chronic obstructive pulmonary disease and asthma, spons…
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CLINICAL_TRIALS research · 2011-08-05Clinical Trial Update: Metabolomic Analysis of Exhaled Breath Condensates in Patients With COPD and Bronchiectasis
This document reports on a clinical trial investigating metabolomic analysis of exhaled breath condensates in patients with COPD and bronchi…
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: Simvastatin in Chronic Obstructive Pulmonary Disease (COPD) [Phase 4]
A Phase 4 clinical trial evaluating simvastatin for chronic obstructive pulmonary disease (including emphysema) is reported, but the status …
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Efficacy of Arm Training in COPD Patients [NA]
A completed clinical trial evaluating the efficacy of arm training in patients with chronic obstructive pulmonary disease.
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Maintenance Schedules Following Pulmonary Rehabilitation [Phase 2]
Phase 2 clinical trial update from the University of East Anglia evaluating maintenance schedules after pulmonary rehabilitation in chronic …
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FDA approval · 2011-07-28FDA Approved: SPIRIVA HANDIHALER — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)
FDA approved a supplemental application for Spiriva HandiHaler (tiotropium bromide) from Boehringer Ingelheim Pharmaceuticals, Inc. This act…
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Hydrogen Peroxide and Nitrite Reduction in Exhaled Breath Condensate of COPD Patients [Phase 1]
Phase 1 study completed evaluating hydrogen peroxide and nitrite reduction in exhaled breath condensate in chronic obstructive pulmonary dis…
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CLINICAL_TRIALS research · 2011-07-26Clinical Trial Update: How Smoking Causes COPD: Examination of Immune System Changes
This clinical trial update reports on research exploring how smoking-triggered immune system changes contribute to chronic obstructive pulmo…
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CLINICAL_TRIALS trial_result · 2011-07-22Clinical Trial Update: Effect of Oxygen-supply on 6-Minute-Walking-Distance of COPD III/IV-patients [NA]
A completed trial evaluating the effect of oxygen supply on the 6-minute walk distance in COPD patients with advanced disease. Results were …
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CLINICAL_TRIALS research · 2011-07-21Clinical Trial Update: Cross-sectional Study to Investigate the Effects of Chronic Obstructive Pulmonary Disease on Daily Life Activities
A completed cross-sectional study sponsored by AstraZeneca examining how chronic obstructive pulmonary disease affects daily life activities…
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CLINICAL_TRIALS research · 2011-07-21Clinical Trial Update: Pulmonary Arterial Pressure Response During Exercise
This entry provides an update on a clinical trial examining pulmonary arterial pressure responses to exercise in COPD patients and healthy s…
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Relative Potency of Inhaled Corticosteroids [Phase 4]
Phase 4 trial update evaluating the relative potency of inhaled corticosteroids in asthma and chronic obstructive pulmonary disease.
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CLINICAL_TRIALS withdrawal · 2011-07-20Clinical Trial Update: HERMES STUDY: Study on the Feasibility and Efficiency of Noninvasive Positive-Pressure Ventilation (NPPV) in Prehospital Care [NA]
The HERMES study evaluating noninvasive positive-pressure ventilation in prehospital care for acute respiratory failure due to COPD exacerba…
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CLINICAL_TRIALS research · 2011-07-13Clinical Trial Update: Using a Closed-loop System for Oxygen Delivery (FreeO2) to Optimize Oxygentherapy in Patients With COPD Exacerbation [NA]
This clinical trial update describes the evaluation of a closed-loop oxygen delivery system (FreeO2) to optimize oxygen therapy in patients …