Chronic Obstructive Pulmonary Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2022-02-03Clinical Trial Update: TRIMBOW® and RELVAR® on Lung Stiffness Reduction Assessed Through Forced Oscillation Technique in Patients With COPD [Phase 4]
A Phase 4 trial assessing lung stiffness reduction with TRIMBOW and RELVAR in COPD has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-02-02Clinical Trial Update: Cycled Testosterone Administration During Pulmonary Rehabilitation in Early Stage COPD [Phase 2, Phase 3]
A clinical trial investigating cycled testosterone during pulmonary rehabilitation in early-stage COPD was withdrawn.
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CLINICAL_TRIALS withdrawal · 2021-09-13Clinical Trial Update: Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD [Phase 3]
Phase 3 trial investigating ipratropium/levalbuterol fixed-dose combination versus salbutamol/ipratropium free combination for acute broncho…
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CLINICAL_TRIALS withdrawal · 2020-09-14Clinical Trial Update: ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study [Phase 4]
A Phase 4 clinical trial for ARALAST NP in COPD with Alpha1-antitrypsin deficiency has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-04-22Clinical Trial Update: Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness Study [Phase 4]
A phase 4 real-world effectiveness study of TRELEGY for chronic obstructive pulmonary disease has been withdrawn.
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EMA withdrawal · 2020-01-15EMA Withdrawn: Aerivio Spiromax (salmeterol xinafoate;fluticasone propionate) — Teva B.V.
EMA withdrew Aerivio Spiromax (salmeterol xinafoate; fluticasone propionate) from Teva B.V., a pulmonary disease and asthma medication.
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CLINICAL_TRIALS withdrawal · 2019-08-07Clinical Trial Update: Effect of Symbicort on HAT and HDAC in Sputum Macrophages of COPD [Phase 4]
A Phase 4 clinical trial investigating the effect of Symbicort on histone acetyltransferase and HDAC activity in sputum macrophages for COPD…
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EMA withdrawal · 2019-07-02EMA Withdrawn: Airexar Spiromax (salmeterol;fluticasone propionate) — Teva B.V.
EMA has withdrawn Airexar Spiromax (salmeterol; fluticasone propionate) from the market.
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CLINICAL_TRIALS withdrawal · 2019-06-19Clinical Trial Update: Erdosteine (Erdotin) Versus Standard Care Plus Placebo on Erdosteine for Treatment of Cough in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) [Phase 4]
Phase 4 trial investigating erdosteine for cough in COPD was withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-02-18Clinical Trial Update: Discovery of the Impact of Targeted Lung Denervation (TLD) on the Severe and Very Severe COPD Population
A clinical trial assessing the impact of Targeted Lung Denervation for severe to very severe COPD has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-02-08Clinical Trial Update: Proprioceptive Postural Control and Diaphragm Paresis
A KU Leuven–sponsored clinical trial on proprioceptive postural control and diaphragm paresis has been withdrawn; the study lists chronic ob…
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CLINICAL_TRIALS withdrawal · 2019-01-31Clinical Trial Update: A Study To Examine The Safety And Efficacy Of PF-00610355 In Moderately Asthmatic Subjects [Phase 2]
Pfizer's Phase 2 study of PF-00610355 in moderately asthmatic subjects has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-08-02Clinical Trial Update: To Assess the Efficacy and Safety of PT010 Compared to PT009 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease [Phase 3]
Phase 3 trial comparing PT010 to PT009 in chronic obstructive pulmonary disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-07-31Clinical Trial Update: Placebo Controlled Evaluation of Sedation and Physiological Response to Intranasal Dexmedetomidine in Severe COPD [Phase 4]
This update notes that the Phase 4 placebo-controlled trial evaluating intranasal dexmedetomidine for sedation and physiological response in…
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CLINICAL_TRIALS withdrawal · 2018-03-08Clinical Trial Update: Evaluating the Clinical Effectiveness of 3D Printing for a Patient-specific Silicone Stent Airway Implant [NA]
The clinical trial evaluating 3D-printed silicone airway stent for COPD and emphysema has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-02-22Clinical Trial Update: Magnesium Sulfate to Prevent Hospitalisation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease [Phase 4]
A Phase 4 trial evaluating magnesium sulfate to prevent hospitalization during acute exacerbations of chronic obstructive pulmonary disease …
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EMA withdrawal · 2018-02-08EMA Withdrawn: Libertek (roflumilast) — AstraZeneca AB
Libertek (roflumilast) has been withdrawn from the market by AstraZeneca AB.
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EMA withdrawal · 2018-02-06EMA Withdrawn: Daliresp (roflumilast) — AstraZeneca AB
The EMA document indicates that Daliresp (roflumilast) has been withdrawn from the market in the EU.
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CLINICAL_TRIALS withdrawal · 2017-11-24Clinical Trial Update: Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating adipose-derived stem cells for chronic obstructive pulmonary disease was withdrawn; no results are rep…
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CLINICAL_TRIALS withdrawal · 2017-10-25Clinical Trial Update: Comparison of Two Positive Expiratory Pressure Devices in Stable COPD Patients [NA]
Rush University Medical Center has withdrawn a clinical trial comparing two positive expiratory pressure devices in stable COPD patients.
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CLINICAL_TRIALS withdrawal · 2017-07-02Clinical Trial Update: To Evaluate Effectiveness of Aclidinium Bromide/Formoterol Fumarate Dihydrate in Chronic Obstructive Pulmonary Disease [Phase 4]
A Phase 4 clinical trial evaluating the fixed-dose combination of aclidinium bromide and formoterol fumarate dihydrate for chronic obstructi…
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CLINICAL_TRIALS withdrawal · 2017-06-23Clinical Trial Update: Novel Therapies for Muco-Obstructive Lung Diseases: Testing the Transnasal Pulmonary Delivery Device in COPD/CB Subjects [NA]
A clinical trial testing a transnasal pulmonary delivery device for COPD and chronic bronchitis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-05-24Clinical Trial Update: Biologic Basis Of Increased Susceptibility Of Smokers To Pulmonary Infection With Mycobacterium Tuberculosis
A clinical trial investigating the biologic basis for increased susceptibility of smokers to pulmonary tuberculosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-05-23Clinical Trial Update: Probiotic Use in Patients With Prior COPD Exacerbation [NA]
A clinical trial investigating probiotic use in patients with prior COPD exacerbation has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-05-02Clinical Trial Update: Lung Volume Reduction Coils for Emphysema in Alpha-1 Antitrypsin Deficiency [NA]
A ClinicalTrials.gov study on Lung Volume Reduction Coils for emphysema in Alpha-1 antitrypsin deficiency has been withdrawn.