Chronic Obstructive Pulmonary Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: QVA vs. Salmeterol/Fluticasone, 52-week Exacerbation Study, FLAME (EFfect of Indacaterol Glycopyronium Vs Fluticasone Salmeterol on COPD Exacerbations) [Phase 3]
This Phase 3 trial compared indacaterol/glycopyrronium (QVA) to salmeterol/fluticasone (Advair) over 52 weeks in COPD and reported results o…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Home Mechanical Ventilation vs Home Oxygen Therapy in COPD [Phase 2, Phase 3]
This clinical trial update reports a Phase 2/Phase 3 study comparing home mechanical ventilation to home oxygen therapy in chronic obstructi…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Emphysema: Physiologic Effects of Nutritional Support [Phase 2]
Phase 2 trial update assessing the physiologic effects of nutritional support in emphysema.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Longitudinal Study of Cortisol and Pulmonary Function
A completed longitudinal study investigating the relationship between cortisol levels and pulmonary function in obstructive lung diseases, i…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Specialized Center of Research in Occupational and Immunologic Lung Disease
A clinical trial update noting completion for a NHLBI-sponsored study on occupational and immunologic lung diseases.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Medication Adherence in COPD--A Self-Regulation Study
A completed NHLBI-funded clinical trial studying how self-regulation strategies affect medication adherence in chronic obstructive pulmonary…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Study to Compare (COPD) Assessment Test in COPD Stage III and IV in a Prophylactic Treatment [NA]
Completed clinical trial evaluating the COPD Assessment Test in patients with stage III/IV COPD receiving prophylactic treatment; results po…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia [Phase 2]
Phase 2 trial of BYM338 in patients with chronic obstructive pulmonary disease and cachexia completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: The Role of Tuberculosis in Chronic Obstructive Lung Disease
This clinical trial update reports on a study assessing how tuberculosis relates to chronic obstructive pulmonary disease.
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Blood, Hair and Lung Concentrations of Metals and Metalloids in Patients With Lung Cancer or Chronic Obstructive Pulmonary Disease [NA]
A completed clinical trial update reporting on blood, hair, and lung concentrations of metals and metalloids in patients with lung cancer or…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Evaluation of the Lungs of Individuals With Lung Disease
A completed clinical trial evaluating lung function in individuals with various lung diseases including bronchitis, emphysema, COPD, and ast…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke
This completed clinical trial investigates how exposure to cigarette smoke modulates genes that regulate cilia length in individuals with ch…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Airway Inflammation and Remodeling in Asthma and COPD.
This document provides an update on a completed clinical trial studying airway inflammation and remodeling in asthma and chronic obstructive…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Evaluation of Benefit of Nebulized Bronchodilators at Home in Severe Chronic Obstructive Pulmonary Disease and Very Severe Steady State [Phase 4]
Phase 4 trial evaluating the benefit of at-home nebulized bronchodilators in patients with severe chronic obstructive pulmonary disease has …
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Effects of Symbicort on the Ventilatory Kinematics [Phase 4]
A Phase 4 trial assessing Symbicort's effects on ventilatory kinematics in chronic obstructive pulmonary disease has been terminated, with r…
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPD [Phase 2]
Phase 2 trial evaluating whether the Aridol inhalation challenge can predict which COPD patients will respond to inhaled corticosteroids.
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: Effect of Glycopyrronium on Morning Symptoms and Pulmonary Function in Patients With Moderate to Severe COPD [Phase 4]
Phase 4 trial assessing the effect of glycopyrronium on morning COPD symptoms and pulmonary function; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Microbiology & Immunology of the Chronically-inflamed Airway
A completed clinical trial update from University Hospital Southampton NHS Foundation Trust focusing on the microbiology and immunology of c…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Lung Health Study (LHS) I and III [Phase 3]
The Lung Health Study I and III Phase 3 trial sponsored by NHLBI has completed. The update indicates the study concerns lung diseases, speci…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Feasibility of Inspiratory Muscle Training in People With COPD Who Decline Pulmonary Rehabilitation [NA]
This clinical trial update reports on the feasibility of inspiratory muscle training in people with chronic obstructive pulmonary disease wh…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Clinical Study of Intermittent Positive Pressure Breathing (IPPB) [Phase 3]
A Phase 3 clinical trial evaluating intermittent positive pressure breathing (IPPB) for lung diseases has completed.
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Study Evaluating the Efficacy and Safety of Fluticasone Furoate/Vilanterol Inhalation Powder (FF/VI) Compared With Vilanterol Inhalation Powder (VI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]
Phase 3 trial comparing fluticasone furoate/vilanterol inhalation powder to vilanterol alone in COPD; study completed with posted results in…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Clinical Study to Investigate Safety and Performance of NeuRx DPS in Patients Undergoing Bilateral Lung Transplantation [NA]
This clinical trial update reports completion of a study evaluating the safety and performance of the NeuRx DPS diaphragmatic pacing system …
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: A Prospective, Cohort Study of Hyperpolarized 3He MRI in Chronic Obstructive Pulmonary Disease
This clinical trial update describes a prospective cohort study using hyperpolarized helium-3 MRI to assess chronic obstructive pulmonary di…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial [Phase 2, Phase 3]
A randomized, double-blind, placebo-controlled pilot trial evaluated TNF-alpha antagonists for acute exacerbations of COPD (Phase 2/3); the …