Chronic Myeloid Leukemia
📧 Sign up to get email alerts when something new happens for Chronic Myeloid Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Retro-prospective Observational Study on Risk of Progression in CP-CML Patients Eligible for TKI Discontinuation
This update notes the completion of a retro-prospective observational study assessing the risk of disease progression in chronic myeloid leu…
-
CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Administration of Donor T Cells With the Caspase-9 Suicide Gene [Phase 1]
A Phase 1 trial evaluating donor T cells engineered with a caspase-9 suicide gene to enable controlled safety in hematologic diseases.
-
CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene [Phase 1]
Phase 1 clinical trial of CASPALLO allodepleted T cells engineered with an inducible caspase-9 suicide gene; the study is currently active b…
-
FDA approval · 2025-07-10FDA Approved: NILOTINIB — Supplemental Application (Cipla USA Inc.)
The FDA approved a supplemental application for nilotinib from Cipla USA Inc., indicating an approved update to the drug's labeling or indic…
-
CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML [Phase 2]
Phase 2 PEARL trial evaluating asciminib for early treatment of chronic myeloid leukemia is currently recruiting.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep [Phase 2]
Phase 2 clinical trial evaluating non-myeloablative preparative regimens followed by umbilical cord blood transplantation for various hemato…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Allo HSCT Using RIC and PTCy for Hematological Diseases [Phase 2]
Phase 2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning and post-transplan…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: ELVN-001 for the Treatment of Chronic Myeloid Leukemia With and Without T315I Mutation in Japanese Participants [Phase 1]
A Phase 1 trial of ELVN-001 in Japanese participants with chronic myeloid leukemia (with or without the T315I mutation) is currently recruit…
-
CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 clinical trial evaluating intensity-modulated total marrow irradiation in fully matched and partially matched allogeneic transplan…
-
CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders [Phase 2]
Phase 2 clinical trial evaluating myeloablative allogeneic hematopoietic stem cell transplantation from related or unrelated donors for a br…
-
CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases [Phase 2]
A Phase 2 clinical trial is testing alpha/beta T cell and CD19+ B cell depletion in allogeneic stem cell transplantation for malignant disea…
-
CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Long-acting Low Dose Ropeginterferon for Chronic Myeloid Leukemia Treated With Bosutinib From Diagnosis [Phase 2]
A Phase 2 trial evaluated long-acting low-dose ropeginterferon in patients with chronic myeloid leukemia who are treated with bosutinib from…
-
CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: TyrosIne Kinase Inhibitors in Chronic Myeloid Leukemia: Efficacy and Tolerability. The TIKlet Study
The TIKlet Study evaluated tyrosine kinase inhibitors for chronic myeloid leukemia and has completed, reporting data on efficacy and tolerab…
-
CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis [Phase 2]
A Phase 2 trial (ABBA CORD) evaluating donor-derived cord blood T cells with abatacept for prophylaxis of acute graft-versus-host disease in…
-
CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Study of Olverembatinib (HQP1351) in Patients With CP-CML [Phase 3]
This report notes a Phase 3 clinical trial evaluating Olverembatinib (HQP1351) in patients with chronic-phase chronic myeloid leukemia, curr…
-
CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP
The document describes a clinical trial evaluating the efficacy and safety of combining third-generation tyrosine kinase inhibitors with aza…
-
CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Ruxolitinib in Treating Participants With Chronic Myeloid Leukemia With Minimal Residual Disease While on Therapy With Tyrosine Kinase Inhibitors [Phase 1]
Phase 1 trial evaluating ruxolitinib in chronic myeloid leukemia patients with minimal residual disease on tyrosine kinase inhibitors was te…
-
CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Blinded Cross-Over Bioequivalence (BE) Trial of Luitpold Azacitidine vs Vidaza [Phase 1]
Phase 1 blinded cross-over bioequivalence trial comparing Luitpold azacitidine with Vidaza has completed, with results posted.
-
CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Study of Predictive Immunological Parameters of Molecular Complete Remission in Patients With Chronic Myelogenous Leukemia in Chronic Phase and Treated With Tyrosine Kinase Inhibitor [NA]
This completed clinical trial update evaluates predictive immunological parameters of molecular complete remission in chronic myeloid leukem…
-
CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Asciminib Used in Consolidation With Imatinib vs. Imatinib to Achieve TFR in CP-CML [Phase 3]
A Phase 3 study evaluating whether adding asciminib to imatinib improves achievement of treatment-free remission in chronic-phase chronic my…
-
CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: TGRX-678 Phase I Oral Pharmacokinetic Study [Phase 1]
A Phase I oral pharmacokinetic study of TGRX-678 for chronic myeloid leukemia has completed.
-
CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
A Phase 1/2 study evaluating venetoclax, ponatinib, and dexamethasone in patients with BCR-ABL1 positive Philadelphia chromosome positive re…
-
CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
Phase 1 study update for Orca-T in recipients undergoing allogeneic transplantation for hematologic malignancies; the trial is currently act…
-
CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Genomics Study in CML Patients With Ponatinib Treatment
A genomics-focused study evaluating ponatinib in patients with chronic myeloid leukemia (BCR-ABL1 positive) has completed.
-
FDA approval · 2025-04-22FDA Approved: DASATINIB — Original Application (Aurobindo Pharma Limited)
FDA approved the original ANDA for dasatinib from Aurobindo Pharma Limited (generic dasatinib).