Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-08-02Clinical Trial Update: Pilot Study of Reduced-Intensity Umbilical Cord Blood Transplantation in Adult Patients Wtih Advanced Hematopoietic Malignancies
The trial evaluating reduced-intensity umbilical cord blood transplantation in adults with advanced hematopoietic malignancies has been term…
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CLINICAL_TRIALS trial_result · 2013-08-02Clinical Trial Update: Unrelated Stem Cell Transplantation for Adults With Hematopoietic Disorders
This clinical trial update notes the completion of an unrelated donor stem cell transplantation study in adults with hematopoietic disorders…
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CLINICAL_TRIALS trial_result · 2013-07-16Clinical Trial Update: Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic Malignancies [Phase 1]
Phase 1 pilot study evaluating haploidentical natural killer cell infusions for poor-prognosis non-AML hematologic malignancies has complete…
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate [Phase 1]
A Phase 1 trial update of tanespimycin (17-N-allylamino-17-demethoxygeldanamycin) in patients with chronic phase chronic myeloid leukemia re…
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CLINICAL_TRIALS trial_result · 2013-07-03Clinical Trial Update: Chemotherapy in Treating Patients With Newly Diagnosed Acute or Chronic Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 2]
This entry updates a Phase 2 chemotherapy trial for newly diagnosed acute myeloid leukemia, chronic myeloid leukemia, and myelodysplastic sy…
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CLINICAL_TRIALS trial_result · 2013-07-02Clinical Trial Update: Evaluation of the Persistence of the Complete Molecular Remission After Stopping Imatinib Chronic Myeloid Leukemia [NA]
This clinical trial update reports on how durable the complete molecular remission is after stopping imatinib in patients with chronic myelo…
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CLINICAL_TRIALS trial_result · 2013-06-27Clinical Trial Update: Dasatinib for Patients Achieving Complete Molecular Response for Cure D-NewS Trial [Phase 2]
This clinical trial update describes a Phase 2 study of dasatinib in patients with chronic myeloid leukemia in chronic phase who have achiev…
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: Combination Chemotherapy and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia [Phase 2]
This phase 2 trial evaluated the combination of chemotherapy with interferon alfa for chronic myeloid leukemia and has completed.
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: Vaccine Therapy in Treating Patients With Chronic Myelogenous Leukemia [Phase 2]
Clinical trial update for a Phase 2 vaccine therapy in chronic myelogenous leukemia. The study status is completed.
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: Monoclonal Antibody Therapy in Treating Patients With Myelodysplastic Syndrome or Relapsed or Refractory Acute Myeloid Leukemia or Chronic Myelogenous Leukemia [Phase 1]
A Phase 1 clinical trial of a monoclonal antibody therapy was conducted in patients with myelodysplastic syndromes, relapsed or refractory a…
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Arsenic Trioxide in Treating Patients With Relapsed or Refractory Chronic Myelogenous Leukemia [Phase 2]
Arsenic trioxide was studied in a Phase 2 trial for relapsed or refractory chronic myeloid leukemia, and the trial has completed. The docume…
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: Prophylactic Transfer of Leukemia-reactive T Cells After Allogeneic Transplantation [Phase 1, Phase 2]
This clinical trial update reports on a completed Phase 1/2 study evaluating prophylactic transfer of leukemia-reactive T cells after alloge…
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CLINICAL_TRIALS trial_result · 2013-06-17Clinical Trial Update: A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) [Phase 3]
A Phase 3 trial comparing imatinib to nilotinib in adults with newly diagnosed Philadelphia chromosome–positive chronic myeloid leukemia in …
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Interferon Alfa and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia [Phase 2]
Phase 2 clinical trial assessing the combination of interferon alfa and imatinib mesylate in patients with chronic myeloid leukemia has been…
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Arsenic Trioxide and Imatinib Mesylate in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated arsenic trioxide in combination with imatinib mesylate for patients with accelerated-phase or blast-ph…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors [Phase 1]
Completed Phase 1 trial evaluating tanespimycin in pediatric patients with recurrent or refractory leukemia or solid tumors.
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FDA approval · 2013-05-22FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Tasigna (nilotinib) to update the product labeling.
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FDA approval · 2013-05-17FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for TASIGNA (nilotinib) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Vorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or Myelodysplastic Syndromes or Myeloproliferative Disorders [Phase 1]
Phase 1 study evaluating a combination of vorinostat, cytarabine, and etoposide in patients with relapsed or refractory acute leukemia, myel…
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CLINICAL_TRIALS trial_result · 2013-05-01Clinical Trial Update: Everolimus and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission After Previous Imatinib Mesylate [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating the combination of everolimus and imatinib mesylate in patients with chronic phase chronic myeloid le…
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CLINICAL_TRIALS trial_result · 2013-04-10Clinical Trial Update: A Phase II Study of Flumatinib Versus Imatinib to Treat Philadelphia Chromosome Positive Chronic Myelogenous Leukemia [Phase 2]
This document details a Phase II clinical trial comparing flumatinib versus imatinib in Philadelphia chromosome-positive chronic myeloid leu…
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CLINICAL_TRIALS trial_result · 2013-04-02Clinical Trial Update: Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory Anemia [Phase 1]
Phase 1 trial evaluating flavopiridol and vorinostat in relapsed or refractory acute leukemias and related myeloid disorders has completed e…
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CLINICAL_TRIALS trial_result · 2013-03-26Clinical Trial Update: Phase II Study for Safety and Efficacy Evaluation of Imatinib Mesylate in Children With Chronic Myeloid Leukemia (CML) Philadelphia Chromosome-positive (Ph+) [Phase 2]
Phase II study evaluating safety and efficacy of imatinib mesylate in children with Philadelphia chromosome-positive chronic myeloid leukemi…
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CLINICAL_TRIALS withdrawal · 2013-03-15Clinical Trial Update: Compassionate Use Ponatinib
This clinical trial update indicates that the compassionate-use program for ponatinib is no longer available.
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies [Phase 3]
Phase 3 study evaluating methotrexate or pentostatin for graft-versus-host disease prophylaxis in risk-adapted allogeneic bone marrow transp…