Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological Malignancies [Phase 1, Phase 2]
Phase 1 and Phase 2 results are reported for allogeneic cytokine-induced killer (CIK) cell immunotherapy given to patients who relapsed afte…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Autologous Cytokine Induced Killer Cells (CIK) for Chronic Myeloid Leukemia (CML) Patients on Standard Drug Therapy [Phase 2]
Phase 2 trial evaluating autologous cytokine-induced killer (CIK) cells for patients with Chronic Myeloid Leukemia on standard drug therapy …
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CLINICAL_TRIALS withdrawal · 2017-02-01Clinical Trial Update: Imatinib Response in Patients With Chronic Myeloid Leukemia (CML) in Function of Abl Polymorphisms
A clinical trial evaluating imatinib response in chronic-phase chronic myeloid leukemia as a function of Abl polymorphisms has been withdraw…
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CLINICAL_TRIALS research · 2017-01-02Clinical Trial Update: Natural History Study of Patients With Chronic Myelogenous Leukemia
This clinical trial update notes the completion of a natural history study of patients with chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Comparative Evaluation of Results of Allogeneic Hematopoietic Stem Cells Versus Ponatinib in CML Patients Carrying a Mutation T315I
This trial compares the outcomes of allogeneic hematopoietic stem cell transplantation versus ponatinib in chronic myeloid leukemia patients…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Study of Cemivil® (Imatinib) in Chronic Myeloid Leukemia Patients in Jordan
A clinical trial evaluating Cemivil (imatinib) for chronic myeloid leukemia in Jordan has completed.
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Evaluating True PCR-negative Rate of Frontline Dasatinib in Early Chronic Phase CML for Therapeutic Harmonization
Clinical trial update evaluating the true PCR-negative rate of frontline dasatinib in early chronic phase chronic myeloid leukemia for thera…
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FDA approval · 2016-11-28FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) submitted by Takeda Pharmaceuticals America, Inc.
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Phase IV, Open-label, Multicenter Study of Dasatinib in Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients With Chronic, Low-grade Non-Hematologic Toxicity to Imatinib [Phase 4]
Phase IV open-label multicenter study evaluating dasatinib in chronic-phase chronic myeloid leukemia patients who have chronic, low-grade no…
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FDA approval · 2016-11-17FDA Approved: BOSULIF — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
The FDA approved a supplemental application for Bosulif (bosutinib) submitted by Pfizer Laboratories Div Pfizer Inc. This action represents …
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CLINICAL_TRIALS trial_result · 2016-11-16Clinical Trial Update: Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 Trial [Phase 4]
Phase 4 trial update showing completion of a study of oral nilotinib (AMN107) in adults with imatinib-resistant or intolerant chronic myeloi…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Discontinuation of Imatinib Mesylate in Patients With Chronic-Phase Chronic Myeloid Leukemia Previously Treated With Interferon-Alpha
The clinical trial evaluating discontinuation of imatinib mesylate in patients with chronic-phase chronic myeloid leukemia previously treate…
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CLINICAL_TRIALS research · 2016-10-31Clinical Trial Update: Study to Assess Efficacy and Safety of Inecalcitol in Imatinib-Treated Residual Chronic Myeloid Leukaemia: INIM Study [Phase 2]
A Phase 2 study to assess the efficacy and safety of ineCalcitol added to imatinib in patients with chronic-phase chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Glivec in Pediatric Chronic Myeloid Leukemia (CML) [Phase 4]
This clinical trial update notes the Phase 4 study of imatinib (Glivec) for pediatric chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating dasatinib in combination with chemotherapy for newly diagnosed acute lymphoblastic leukemia, including B…
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Evaluating the Safety of Zileuton (Zyflo®) in Combination With Dasatinib (Sprycel®) in Chronic Myelogenous Leukemia [Phase 1]
Phase 1 trial evaluating the safety of combining zileuton with dasatinib in chronic myeloid leukemia has been terminated.
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CLINICAL_TRIALS research · 2016-09-30Clinical Trial Update: Treatment With Second Generation Tyrosine Kinase Inhibitors (2G TKI) Post Imatinib Failure Survey
This clinical trial update reports on treatment with second-generation tyrosine kinase inhibitors after imatinib failure in chronic-phase ch…
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FDA approval · 2016-09-27FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for Tasigna (nilotinib) from Novartis Pharmaceuticals Corporation, resulting in updated labeling…
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FDA approval · 2016-09-27FDA Approved: DASATINIB — Supplemental Application (Prasco Laboratories)
FDA approved a supplemental application for dasatinib submitted by Prasco Laboratories.
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CLINICAL_TRIALS research · 2016-09-16Clinical Trial Update: National Observatory of Chronic Myeloid Leukemia Adolescent and Young Adults Treated With Tyrosine Kinase Inhibitors in First Intent
Clinical trial update on first-line tyrosine kinase inhibitor therapy for adolescent and young adult patients with chronic myeloid leukemia.…
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Patient Reported Outcomes in Chronic Myeloid Leukemia
This update notes the completion of a clinical trial evaluating patient-reported outcomes in Chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Pioglityazone and Imatinib for CML Patients [Phase 2]
Phase 2 trial examining pioglitazone in combination with imatinib for chronic myeloid leukemia has completed; no results are provided in the…
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FDA approval · 2016-09-07FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) from Takeda Pharmaceuticals America, resulting in changes to t…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: Population Pharmacokinetics of Imatinib in CML Patients in Iran
Clinical trial update on the population pharmacokinetics of imatinib in chronic myeloid leukemia patients in Iran. The study is terminated.
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FDA label_change · 2016-08-31FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
The FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) by Takeda Pharmaceuticals America, Inc., resulting in labe…