Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2017-12-05Clinical Trial Update: StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies [Phase 2]
Phase 2 trial evaluating StemRegenin-1-expanded versus unexpanded umbilical cord blood for high-risk hematologic malignancies has been withd…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: AHN-12 Biodistribution in Advanced Leukemia [Phase 1]
A Phase 1 trial of the investigational agent AHN-12 focusing on biodistribution in advanced leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Chemotherapy, Filgrastim and Peripheral Stem Cell Transplantation in Patients With Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial update evaluating chemotherapy with Filgrastim and peripheral stem cell transplantation in patients with chronic myeloid leuke…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia [NA]
The document reports the completion of a clinical trial evaluating donor lymphocyte infusion for relapsed leukemia after transplantation acr…
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CLINICAL_TRIALS research · 2017-11-28Clinical Trial Update: Sleep Assessment in CML
This entry reports an ongoing clinical trial from HaEmek Medical Center examining sleep assessment in patients with chronic myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2017-11-24Clinical Trial Update: A Prospective Randomized Phase II Study Evaluating the Monitoring of Imatinib Mesylate Plasmatic Through Level in Patients Newly Diagnosed With CP-CML [Phase 2]
This Phase II randomized trial evaluates whether monitoring trough plasma levels of imatinib improves treatment management in patients with …
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CLINICAL_TRIALS research · 2017-11-21Clinical Trial Update: Regional Central Database Recording of Chronic Myeloid Leukemia
A clinical trial update regarding a regional central database recording cases of chronic myeloid leukemia, sponsored by Institut Bergonié.
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FDA approval · 2017-11-20FDA Approved: BUSULFAN — Original Application (Mylan Institutional LLC)
FDA approved a generic busulfan under an Original Application with Mylan Institutional LLC.
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies [Phase 1]
A Phase 1 trial evaluated ABT-348 as a standalone therapy and in combination with azacitidine for advanced hematologic malignancies; the stu…
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FDA approval · 2017-11-09FDA Approved: DASATINIB — Supplemental Application (Prasco Laboratories)
The FDA approved a supplemental application for dasatinib filed by Prasco Laboratories, resulting in updated labeling for this drug.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Study to Assess Efficacy and Safety of Nilotinib 300mg Twice Daily in Patients With Philadelphia Positive Chronic Myeloid Leukaemia (CML) in Chronic Phase Who Are Intolerant to Prior Tyrosine Kinase Inhibitors. [Phase 3]
A Phase 3 trial evaluating nilotinib 300 mg twice daily in Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase patien…
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CLINICAL_TRIALS trial_result · 2017-10-10Clinical Trial Update: Nilotinib Versus Imatinib in Treatment of Patients With Newly Diagnosed Chronic Myeloid Leukemia [EARLY_Phase 1]
This early-phase trial compares nilotinib to imatinib in patients with newly diagnosed chronic myeloid leukemia to assess safety and prelimi…
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FDA approval · 2017-09-29FDA Approved: GLEEVEC — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approves a supplemental NDA for GLEEVEC (imatinib mesylate) filed by Novartis Pharmaceuticals Corporation, resulting in changes to the p…
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Randomized Study Comparing the Effect of Dasatinib and Imatinib on Malignant Stem Cells in Chronic Myeloid Leukemia [Phase 2]
A Phase 2 randomized study comparing dasatinib and imatinib on malignant stem cells in chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Safety and Efficacy of Pegylated IFN-alpha 2B Added to Dasatinib in Newly Diagnosed Chronic Phase Myeloid Leukemia [Phase 2]
Phase 2 trial assessing safety and efficacy of pegylated interferon-alpha-2b added to dasatinib in newly diagnosed chronic phase myeloid leu…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Safety and Efficacy Study of PRI-724 in Subjects With Advanced Myeloid Malignancies [Phase 1, Phase 2]
A completed Phase 1/2 study of PRI-724 in adults with advanced myeloid malignancies (acute and chronic myeloid leukemia) evaluated safety an…
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FDA approval · 2017-08-10FDA Approved: DASATINIB — Supplemental Application (Prasco Laboratories)
The FDA approved a supplemental application for dasatinib submitted by Prasco Laboratories.
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: The Efficacy and Safety of Induction-Maintenance Protocol for Patients With Chronic Myelogenous Leukaemia [Phase 2]
Phase 2 trial update evaluating an induction-maintenance treatment protocol for Philadelphia chromosome-positive chronic myeloid leukemia, r…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Frequency and Severity of Pleural Effusion Associated With the Use of Dasatinib in Patients With Chronic Myeloid Leukemia. A Descriptive, Mexican Multicenter Study
This Mexican multicenter descriptive study reports the frequency and severity of pleural effusions in chronic myeloid leukemia patients trea…
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CLINICAL_TRIALS research · 2017-07-13Clinical Trial Update: Low-dose Dasatinib as First-line Treatment for Chronic Myeloid Leukemia [Phase 4]
A Phase 4 clinical trial update on using low-dose dasatinib as first-line therapy for chronic myeloid leukemia, with the trial's current sta…
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CLINICAL_TRIALS research · 2017-07-11Clinical Trial Update: Myeloid Derived Suppressor Cells and Chronic Myeloid Leukemia [NA]
This clinical trial update from Assiut University investigates the role of myeloid-derived suppressor cells in patients with chronic myeloid…
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CLINICAL_TRIALS trial_result · 2017-07-07Clinical Trial Update: An Extension Study of RO5045337 in Participants Participating in Previous Roche-sponsored Cancer Studies [Phase 1]
Hoffmann-La Roche announced completion of an extension study for RO5045337 in participants from previous Roche cancer studies, involving chr…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Phase II Study Testing the Tolerability and the Efficacy of Bosutinib in Chronic Phase CML Patients [Phase 2]
Phase II trial evaluating the tolerability and efficacy of bosutinib in patients with chronic myeloid leukemia in the chronic phase.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Imatinib (Gleevec(Registered Trademark)) to Treat Chronic Myelomonocytic Leukemia and Atypical Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 clinical trial evaluated imatinib (Gleevec) for chronic myelomonocytic leukemia, chronic myeloid leukemia, and atypical chronic my…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Collection of Blood and Bone Marrow Samples From Select Patients With CML to Measure Minimal Residual Disease
Clinical trial update describing the collection of blood and bone marrow samples from select patients with chronic myeloid leukemia to measu…