Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Nilotinib in PH+, BCR-, ABL+ CML Patients [Phase 3]
Phase 3 clinical trial update for nilotinib in Philadelphia-positive, BCR-ABL-positive chronic myeloid leukemia patients, completed.
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Nilotinib in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 clinical trial update evaluating nilotinib for newly diagnosed chronic phase chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Chronic Myelod Leukemia Registry at Asan Medical Center
The Chronic Myeloid Leukemia Registry at Asan Medical Center has been terminated. The registry covers chronic myeloid leukemia in chronic ph…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 trial update reporting completion of a study evaluating ultra-low-dose interleukin-2 as graft-versus-host disease prophylaxis in hap…
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Glinib in Newly Diagnosed CML Patients [Phase 4]
A Phase 4 study evaluating Glinib in newly diagnosed chronic myeloid leukemia patients has been terminated. The trial aimed to assess effica…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Relapsed Malignant Blood Cancer After Allogeneic Hematopoietic Stem Cell Transplantation
The National Cancer Institute-sponsored clinical trial assessing relapse in malignant blood cancers after allogeneic hematopoietic stem cell…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Tipifarnib in Treating Patients With Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or Undifferentiated Myeloproliferative Disorders [Phase 1, Phase 2]
The document notes the completion of a Phase 1/2 clinical trial evaluating tipifarnib in patients with chronic myeloid leukemia, chronic mye…
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: Evaluation of the Therapeutic Effect of HU Pulse Therapy for CML Patients [Phase 3]
A Phase 3 clinical trial evaluating hydroxyurea pulse therapy for chronic myeloid leukemia; this update provides current status of the study…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients. [Phase 2]
Phase II open-label study assessing oral nilotinib in pediatric patients with Philadelphia chromosome–positive chronic myeloid leukemia; stu…
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological Malignancies [Phase 1]
This update describes safety data from a Phase 1 study of AP24534 (ponatinib) in patients with chronic myeloid leukemia and other hematologi…
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: Imatinib Mesylate With or Without Interferon Alfa or Cytarabine Compared With Interferon Alfa Followed by Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Phase 3]
Phase 3 trial evaluating Imatinib Mesylate with or without Interferon Alfa or Cytarabine versus Interferon Alfa followed by donor stem cell …
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: Phase III Study of Compound Formula Realgar-Indigo Naturalis Plus Imatinib Versus Placebo Plus Imatinib in Adult CML-CP Patients With Ph+ [Phase 3]
A Phase 3 trial comparing Realgar-Indigo Naturalis plus Imatinib to placebo plus Imatinib in adults with Philadelphia chromosome-positive ch…
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: Comparison of Imatinib Versus Dasatinib in Patients With Newly-diagnosed Chronic Phase Chronic Myeloid Leukaemia [Phase 3]
A Phase 3 trial comparing imatinib to dasatinib in newly diagnosed chronic phase chronic myeloid leukemia has completed. The update provides…
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CLINICAL_TRIALS trial_result · 2018-04-10Clinical Trial Update: Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies [Phase 2]
A Phase 2 trial evaluated haplotype-mismatched hematopoietic stem cell transplantation in patients with hematological malignancies. The stud…
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Multicenter Trial Estimating the Persistence of Molecular Remission in Chronic Myeloid Leukaemia in Long Term After Stopping Imatinib [NA]
This completed multicenter trial investigates how long patients with chronic myeloid leukemia stay in molecular remission after stopping ima…
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: The Study of the Efficacy and the Safety of Flumatinib vs Imatinib as First Line Treatment in Patients With CML [Phase 3]
A Phase 3 trial comparing flumatinib to imatinib as first-line therapy for chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2018-01-05Clinical Trial Update: A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to Imatinib [Phase 2]
Phase II pediatric study evaluating dasatinib for newly diagnosed chronic phase chronic myeloid leukemia or Philadelphia chromosome-positive…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: AHN-12 Biodistribution in Advanced Leukemia [Phase 1]
A Phase 1 trial of the investigational agent AHN-12 focusing on biodistribution in advanced leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Chemotherapy, Filgrastim and Peripheral Stem Cell Transplantation in Patients With Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial update evaluating chemotherapy with Filgrastim and peripheral stem cell transplantation in patients with chronic myeloid leuke…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia [NA]
The document reports the completion of a clinical trial evaluating donor lymphocyte infusion for relapsed leukemia after transplantation acr…
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CLINICAL_TRIALS trial_result · 2017-11-24Clinical Trial Update: A Prospective Randomized Phase II Study Evaluating the Monitoring of Imatinib Mesylate Plasmatic Through Level in Patients Newly Diagnosed With CP-CML [Phase 2]
This Phase II randomized trial evaluates whether monitoring trough plasma levels of imatinib improves treatment management in patients with …
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies [Phase 1]
A Phase 1 trial evaluated ABT-348 as a standalone therapy and in combination with azacitidine for advanced hematologic malignancies; the stu…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Study to Assess Efficacy and Safety of Nilotinib 300mg Twice Daily in Patients With Philadelphia Positive Chronic Myeloid Leukaemia (CML) in Chronic Phase Who Are Intolerant to Prior Tyrosine Kinase Inhibitors. [Phase 3]
A Phase 3 trial evaluating nilotinib 300 mg twice daily in Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase patien…
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CLINICAL_TRIALS trial_result · 2017-10-10Clinical Trial Update: Nilotinib Versus Imatinib in Treatment of Patients With Newly Diagnosed Chronic Myeloid Leukemia [EARLY_Phase 1]
This early-phase trial compares nilotinib to imatinib in patients with newly diagnosed chronic myeloid leukemia to assess safety and prelimi…
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Randomized Study Comparing the Effect of Dasatinib and Imatinib on Malignant Stem Cells in Chronic Myeloid Leukemia [Phase 2]
A Phase 2 randomized study comparing dasatinib and imatinib on malignant stem cells in chronic myeloid leukemia has completed.