Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-11Clinical Trial Update: Phase II Nilotinib With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) [Phase 2]
Phase II trial updating nilotinib use in newly diagnosed chronic phase chronic myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: Ponatinib - Frontline for Chronic Myeloid Leukemia (CML) in Accelerated Phase (AP) [Phase 2]
Phase 2 trial evaluating ponatinib as frontline therapy for chronic myeloid leukemia in accelerated phase; the study was terminated and resu…
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: A Study of Imatinib and Nilotinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase [Phase 3]
Phase 3 trial update on imatinib and nilotinib in chronic myeloid leukemia in chronic phase; results posted after completion.
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: Consolidation Treatment With Ponatinib 15 mg on Treatment Free-Remission Rate in Patients With Chronic Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating consolidation treatment with ponatinib 15 mg on treatment-free remission rates in patients with chronic my…
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CLINICAL_TRIALS trial_result · 2019-05-28Clinical Trial Update: Nilotinib + Pegylated Interferon Alpha 2a for Untreated Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 clinical trial evaluating nilotinib in combination with pegylated interferon alpha-2a for untreated chronic phase chronic myeloid le…
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CLINICAL_TRIALS trial_result · 2019-05-01Clinical Trial Update: Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies [Phase 2]
Phase 2 clinical trial evaluating BL-8040 for mobilizing donor hematopoietic stem cells to enable allogeneic transplantation in patients wit…
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CLINICAL_TRIALS trial_result · 2019-04-11Clinical Trial Update: Study of Dasatinib vs Imatinib in Patients With Chronic Myeloid Leukemia (CML) Who Did Not Have Favorable Response to Imatinib [Phase 2]
Phase 2 trial comparing dasatinib to imatinib in patients with chronic phase chronic myeloid leukemia who did not respond favorably to imati…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203) [Phase 2]
Phase 2 study evaluating novel approaches to prevent graft-versus-host disease after allogeneic hematopoietic cell transplantation, with res…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Dasatinib Versus Nilotinib for Treatment Naïve Chronic Myeloid Leukemia [Phase 3]
Phase 3 trial comparing dasatinib and nilotinib in treatment-naïve chronic myeloid leukemia (chronic phase) has been terminated.
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CLINICAL_TRIALS trial_result · 2019-01-18Clinical Trial Update: Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation [Phase 1]
Phase 1 trial evaluating inducible regulatory T cells (iTregs) in non-myeloablative sibling donor peripheral blood stem cell transplantation…
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CLINICAL_TRIALS trial_result · 2019-01-17Clinical Trial Update: A Phase 1B Study to Investigate the Safety and Preliminary Efficacy for the Combination of Dasatinib Plus Nivolumab in Patients With Chronic Myeloid Leukemia [Phase 1]
A Phase 1B study evaluating safety and preliminary efficacy of Dasatinib in combination with Nivolumab in Chronic Myeloid Leukemia has been …
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CLINICAL_TRIALS trial_result · 2019-01-14Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety,and Efficacy of Omacetaxine Given Subcutaneously as a Fixed Dose in Patients With Chronic Phase (CP) or Accelerated Phase (AP) Chronic Myeloid Leukemia (CML) (Referred to as the SYNSINCT Study) [Phase 1, Phase 2]
A two-phase study evaluating subcutaneous omacetaxine in fixed dose for chronic phase or accelerated phase chronic myeloid leukemia has been…
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: Pioglitazone and Tyrosine Kinase Inhibitor in Treating Patients With Relapsed Chronic Myeloid Leukemia [Phase 2]
Phase 2 trial investigating pioglitazone in combination with a tyrosine kinase inhibitor for relapsed chronic myeloid leukemia (BCR-ABL1 pos…
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CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 results from a study using donor umbilical cord blood stem cell transplants in patients with hematologic malignancies have been post…
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CLINICAL_TRIALS trial_result · 2018-11-14Clinical Trial Update: A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Phase 3]
Phase 3 trial comparing bosutinib to imatinib in newly diagnosed chronic phase CML; study completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-13Clinical Trial Update: Interferon and GM-CSF Compared With Imatinib Mesylate and Vaccine Therapy in Patients With Chronic Phase CML on a TKI [Phase 2]
A Phase 2 clinical trial comparing interferon and GM-CSF with imatinib mesylate and vaccine therapy in chronic phase CML patients on a TKI h…
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CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: Dasatinib or Nilotinib Followed by Imatinib in Patients With Newly Diagnosed, Chronic Phase Chronic Myeloid Leukemia [Phase 2]
Phase 2 trial investigating sequences of dasatinib or nilotinib followed by imatinib in newly diagnosed chronic phase chronic myeloid leukem…
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CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: Open-Label Study Evaluating Dasatinib Therapy Discontinuation in Patients With Chronic Phase Chronic Myeloid Leukemia With Stable Complete Molecular Response [Phase 2]
A Phase 2 open-label study evaluating stopping dasatinib in patients with chronic phase chronic myeloid leukemia who have stable complete mo…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS) [Phase 2, Phase 3]
A nonmyeloablative preparative regimen using Mylotarg (gemtuzumab ozogamicin) was studied in Phase 2/Phase 3 trials for high-risk acute myel…
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CLINICAL_TRIALS trial_result · 2018-10-30Clinical Trial Update: Phase II Study of SCH66336, A Farnesyltransferase Inhibitor in Chronic Myelogenous Leukemia (CML) [Phase 2]
Phase II trial update for SCH66336 (a farnesyltransferase inhibitor) in chronic myelogenous leukemia has completed.
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Therapy of Early Chronic Phase CML With Higher-Dose Gleevec, Alpha Interferon, and Low-Dose Ara-C [Phase 2]
Phase 2 trial of higher-dose Gleevec (imatinib), alpha interferon, and low-dose cytarabine for early chronic phase chronic myeloid leukemia …
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: WT1 TCR Gene Therapy for Leukaemia: A Phase I/II Safety and Toxicity Study [Phase 1, Phase 2]
A Phase I/II safety and toxicity study of WT1 TCR gene therapy for acute myeloid leukemia and chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: Experimental Bone Marrow Transplant Protocol [Phase 2]
Phase 2 clinical trial update for an experimental bone marrow transplant protocol that investigated treatment in blood cancer conditions; st…
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: A Study To Describe The Real World Use Of Bosutinib In The UK And Netherlands
A completed observational trial describing real-world use of bosutinib in the UK and Netherlands for chronic myeloid leukemia, with results …
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Vaccine Therapy in Treating Patients With Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia [Phase 2]
Phase 2 clinical trial update for a vaccine therapy in Philadelphia chromosome-positive chronic myeloid leukemia (CML) completed; results po…