Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-01-07Clinical Trial Update: Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML) [Phase 2]
Phase 2 trial evaluating azacitidine after allogeneic stem cell transplantation for chronic myeloid leukemia has been completed with posted …
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CLINICAL_TRIALS trial_result · 2020-12-31Clinical Trial Update: Phase III Trial Evaluating the Effectiveness of a Dose Adjustment of Imatinib Mesylate on the Molecular Response [Phase 3]
Phase III trial assessing a dose adjustment of imatinib mesylate for molecular response in chronic-phase myeloid leukemia; study terminated …
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Clofarabine Combinations in Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS) and Myeloid Blast Phase Chronic Myeloid Leukemia (CML) [Phase 2]
Phase 2 trial update of clo farabine combinations in relapsed/refractory AML and MDS (and myeloid blast phase CML) with results posted.
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study) [Phase 1, Phase 2]
Extension study evaluating nilotinib in adults with imatinib-resistant/intolerant CML or relapse/refractory Philadelphia-positive ALL; compl…
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: Study of Bosutinib in Japanese Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial updates bosutinib in Japanese adults with newly diagnosed chronic phase chronic myeloid leukemia; results posted after complet…
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CLINICAL_TRIALS trial_result · 2020-11-05Clinical Trial Update: Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs Therapy [Phase 2]
Phase 2 trial evaluating allogeneic stem cell transplantation for chronic myeloid leukemia patients failing TKI therapy has completed.
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia [Phase 1, Phase 2]
Phase I/II study evaluating nilotinib combined with ruxolitinib in TKI-resistant Philadelphia chromosome-positive leukemias; trial status co…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: An Open-Label, Phase I/II Study of Two Different Schedules of Dasatinib (Sprycel) and Decitabine (Dacogen) Used in Combination for Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia (Protocol CA180357) [Phase 1, Phase 2]
Open-label Phase I/II study evaluating two schedules of dasatinib plus decitabine in accelerated or blastic phase chronic myeloid leukemia; …
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: A Study of REduction And DIscontinuation Treatment of TKI (Imatinib, Nilotinib, Dasatinib and Bosutinib) [Phase 2]
Phase 2 clinical trial evaluating reduction and discontinuation strategies for TKIs imatinib, nilotinib, dasatinib, and bosutinib in BCR-ABL…
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CLINICAL_TRIALS trial_result · 2020-09-14Clinical Trial Update: Malaysia Stop Tyrosine Kinase Inhibitor Trial [Phase 3]
A Phase 3 clinical trial update from Malaysia regarding a Tyrosine Kinase Inhibitor for leukemia, chronic myeloid leukemia; current status i…
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CLINICAL_TRIALS trial_result · 2020-09-01Clinical Trial Update: Study of Nilotinib as First Line Treatment in Philadelphia Chromosome Positive(Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) [Phase 2]
Phase 2 trial update on nilotinib as first-line treatment for Philadelphia chromosome–positive chronic myeloid leukemia in chronic phase.
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CLINICAL_TRIALS trial_result · 2020-08-12Clinical Trial Update: IL-15 Super Agonist ALT-803 to Treat Relapse Of Hematologic Malignancy After Allogeneic SCT [Phase 1, Phase 2]
Clinical trial update on an IL-15 super agonist ALT-803 for relapse of hematologic malignancies after allogeneic stem cell transplant, compl…
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CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: Therapies in Combination or Sequentially With Tyrosine Kinase Inhibitors (TKIs) in Chronic Phase Chronic Myelogenous Leukemia Patients in CCR (ACTIW) [Phase 1, Phase 2]
Phase 1/2 trial evaluating combinations or sequential use of therapies with tyrosine kinase inhibitors in chronic phase chronic myeloid leuk…
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CLINICAL_TRIALS trial_result · 2020-04-13Clinical Trial Update: STI571 ProspectIve RandomIzed Trial: SPIRIT [Phase 3]
Phase 3 randomized trial update for STI571 (imatinib) in chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: A Study That Switched Patients From Imatinib to Nilotinib and Then Was Followed by Treatment Cessation [Phase 2]
Phase 2 trial updating patients with chronic myeloid leukemia who switched from imatinib to nilotinib and then underwent treatment cessation…
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CLINICAL_TRIALS trial_result · 2020-02-17Clinical Trial Update: Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene [Phase 1, Phase 2]
Clinical trial update evaluating tolerability, safety, pharmacokinetics and preliminary efficacy of PF-114 in adults with Ph+ chronic myeloi…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Combination of Dasatinib and Peg-Interferon Alpha 2b in First Line for Chronic Myeloid Leukemia in Chronic Phase [Phase 2]
A Phase 2 trial evaluated the combination of dasatinib and peg-interferon alfa-2b as first-line therapy for chronic phase chronic myeloid le…
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts [Phase 2]
A Phase 2 clinical trial evaluating T cell depletion in recipients of HLA haploidentical related donor stem cell grafts for various hematolo…
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT [Phase 1]
Phase 1 trial exploring a calcineurin inhibitor-free graft-versus-host disease prevention regimen after related haploidentical peripheral bl…
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CLINICAL_TRIALS trial_result · 2020-01-10Clinical Trial Update: Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Older Patients With Chronic Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial evaluating fludarabine phosphate with low-dose total-body irradiation and peripheral blood stem cell transplant, fo…
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CLINICAL_TRIALS trial_result · 2019-12-20Clinical Trial Update: Compliance: Role Emerges for Success in Chronic Myelogenous Leukaemia (CML): Evaluation aND Optimisation [Phase 4]
Phase 4 trial update on Chronic Myelogenous Leukemia (CML) evaluating compliance and optimization strategies.
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CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: Validation of Digital-PCR Analysis Through Programmed Imatinib Interruption in PCR Negative CML Patients [Phase 4]
Phase 4 trial update evaluating digital-PCR analysis during interrupted imatinib therapy in PCR-negative chronic myeloid leukemia patients.
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CLINICAL_TRIALS trial_result · 2019-12-02Clinical Trial Update: An Open-label, Randomised Multicenter Phase 3b Study to Determine the Confirmed Rate of Molecular Response ≥ 4 Log (MR4) at Two Years [Phase 3]
Phase 3b open-label randomized study in chronic myeloid leukemia investigating confirmed molecular response rate over two years; trial termi…
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CLINICAL_TRIALS trial_result · 2019-11-29Clinical Trial Update: Treatment-free Remission Accomplished With Dasatinib in Patients With CML [Phase 2]
Phase 2 trial reporting treatment-free remission achieved with dasatinib in chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.