Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Stem Cell Transplantation for Patients With Cancers of the Blood [Phase 2]
Phase 2 trial update reporting results from stem cell transplantation for patients with blood cancers, including chronic myeloid leukemia, c…
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CLINICAL_TRIALS trial_result · 2014-12-15Clinical Trial Update: Efficacy and Safety of Imatinib Mesylate as First-line Treatment for the Patients With Chronic Phase of Chronic Myeloid Leukemia [Phase 4]
This document provides an update on a Phase 4 trial evaluating the efficacy and safety of imatinib mesylate as first-line treatment for pati…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Intermittent Imatinib Treatment in Chronic Myeloid Leukemia and Philadelphia Chromosome (Ph+CML) Patients Who Achieved a Complete Cytogenetic Response (CCgR) on Standard Imatinib Therapy [Phase 2]
Phase 2 study assessing intermittent dosing of imatinib in patients with chronic myeloid leukemia who achieved complete cytogenetic response…
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CLINICAL_TRIALS trial_result · 2014-10-31Clinical Trial Update: A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating withdrawal of immunosuppression and donor lymphocyte infusions after allogeneic transplant in pediatric hematologic…
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CLINICAL_TRIALS trial_result · 2014-10-24Clinical Trial Update: Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Steps [Phase 1, Phase 2]
This Phase 1/2 study evaluated a two-step reduced-intensity conditioning regimen for bone marrow transplantation in patients with hematologi…
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CLINICAL_TRIALS trial_result · 2014-10-22Clinical Trial Update: Advanced Chronic Myelogenous Leukemia (CML) - Follow On: Study of BMS-354825 in Subjects With CML [Phase 3]
This is a Phase 3 clinical trial update for dasatinib (BMS-354825) in chronic myeloid leukemia; the study is completed and results were post…
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CLINICAL_TRIALS trial_result · 2014-10-21Clinical Trial Update: Ponatinib in Newly Diagnosed Chronic Myeloid Leukemia (CML) (EPIC) [Phase 3]
EPIC is a Phase 3 trial evaluating ponatinib as initial therapy in newly diagnosed chronic myeloid leukemia; the study was terminated, with …
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: A Clinical Trial to Compare the Pharmacokinetics of Imatinib Mesylate Tablet 400mg (1 Tablet) and Glivec Film-coated Tablet 100mg (4 Tablets)(Phase I) [Phase 1]
A Phase I pharmacokinetic study comparing Imatinib Mesylate 400 mg (1 tablet) with Glivec 100 mg film-coated tablet (4 tablets) to assess PK…
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CLINICAL_TRIALS trial_result · 2014-09-18Clinical Trial Update: STA-9090 for Treatment of AML, CML, MDS and Myeloproliferative Disorders [Phase 1]
Phase 1 clinical trial of ganetespib (STA-9090) for acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myelopr…
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CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous Leukemia [Phase 1]
This Clinical Trial Update reports on a Phase 1 study evaluating the combination of panobinostat (LBH589) and imatinib mesylate in patients …
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: Study Safety and Preliminary Efficacy of DCC-2036 in Patients With Leukemias (Ph+ CML With T315I Mutation) [Phase 1]
This update reports safety data and preliminary efficacy signals from a Phase 1 study of DCC-2036 in patients with Philadelphia chromosome–p…
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Pharmacogenomics Validation for Imatinib in Chronic Myeloid Leukemia
This completed study provides pharmacogenomic validation for response to imatinib in patients with chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers [Phase 2]
Phase 2 clinical trial update evaluating peptide vaccinations in patients with low-risk myeloid cancers, including myelodysplastic syndrome …
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy [Phase 2]
Phase 2 trial of WT1 peptide vaccine in high-risk hematologic malignancies (myelodysplastic syndrome, acute myeloid leukemia, and chronic my…
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Low Dose IL-2, Hematopoietic Stem Cell Transplantation, IL2 for GVHD [Phase 2]
Phase 2 trial update evaluating low-dose interleukin-2 in patients undergoing allogeneic hematopoietic stem cell transplantation to address …
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CLINICAL_TRIALS trial_result · 2014-06-30Clinical Trial Update: TALL-104 and Gleevec in Chronic Myelogenous Leukemia Patients [Phase 2]
Phase 2 trial update of TALL-104 with Gleevec for chronic myeloid leukemia; the study was terminated and results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-06-30Clinical Trial Update: Open Label Study of Subcutaneous Homoharringtonine (Omacetaxine Mepesuccinate) in Patients With Advanced CML [Phase 2]
Open-label Phase 2 trial evaluating subcutaneous homoharringtonine (omacetaxine mepesuccinate) in patients with advanced chronic myeloid leu…
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Comparative Bioequivalence Study in Adult Patients Suffering From Chronic Myeloid Leukemia & Gastrointestinal Stromal Tumor Under Fed Conditions [Phase 2, Phase 3]
This update reports the completion of a Phase 2/3 comparative bioequivalence study in adults with chronic myeloid leukemia and gastrointesti…
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CLINICAL_TRIALS trial_result · 2014-06-17Clinical Trial Update: Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 study evaluating vorinostat with or without isotretinoin in pediatric patients with recurrent or refractory solid tumors, lymphoma, …
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CLINICAL_TRIALS trial_result · 2014-06-04Clinical Trial Update: Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive Leukemias [Phase 2]
Phase 2 study results of bosutinib (SKI-606) in Japanese patients with Philadelphia chromosome-positive leukemias are reported, focusing on …
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CLINICAL_TRIALS trial_result · 2014-06-03Clinical Trial Update: Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation [Phase 2]
Phase 2 trial update of homoharringtonine (Omacetaxine mepesuccinate) in chronic myeloid leukemia with the T315I BCR-ABL mutation; results p…
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: Dasatinib Combination Therapy With the Smoothened (SMO) Inhibitor BMS-833923 in Chronic Myeloid Leukemia (CML) [Phase 1, Phase 2]
A Phase 1/2 study evaluated dasatinib in combination with the SMO inhibitor BMS-833923 for chronic myeloid leukemia and has completed with r…
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer [Phase 3]
Phase 3 trial evaluating total-body irradiation with or without fludarabine phosphate followed by donor stem cell transplant in hematologic …
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CLINICAL_TRIALS trial_result · 2014-05-08Clinical Trial Update: Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood [Phase 1, Phase 2]
Phase 1/2 trial evaluating Wilms' Tumor 1 protein vaccine for blood cancers has completed. Results were posted on 2014-05-08.
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 trial evaluating obatoclax mesylate in combination with vincristine, doxorubicin, and dexrazoxane in pediatric patients with relapse…