Chronic Myeloid Leukemia
📧 Sign up to get email alerts when something new happens for Chronic Myeloid Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2015-09-15Clinical Trial Update: A Study of Complete Molecular Response for Chronic Myeloid Leukemia in Chronic Phase Patients, Treated With Dasatinib [Phase 2]
A Phase 2 trial evaluating dasatinib in chronic myeloid leukemia in chronic phase reports results related to complete molecular response.
-
CLINICAL_TRIALS trial_result · 2015-09-15Clinical Trial Update: A Study of Dasatinib in Patients With Imatinib Resistant or Intolerant Chronic Myeloid Leukemia [Phase 2]
A Phase 2 trial evaluating dasatinib in patients with imatinib-resistant or -intolerant chronic myeloid leukemia has completed. The update s…
-
CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Pulmonary Vasculopathy Under Second-line Therapy of Chronic Myeloid Leukemia
This is a completed clinical trial conducted by the Medical University of Graz investigating pulmonary vasculopathy in patients with chronic…
-
CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: MK0457 in Patients With Leukemia (0457-003) [Phase 1]
Phase 1 trial update for MK-0457 (VX-680) in leukemia patients has completed; the study included chronic myeloid leukemia in blast crisis, a…
-
CLINICAL_TRIALS trial_result · 2015-08-21Clinical Trial Update: Study of XL228 in Subjects With Chronic Myeloid Leukemia or Philadelphia-Chromosome-Positive Acute Lymphocytic Leukemia [Phase 1]
Clinical trial update for XL228 in chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia; the Phase 1 s…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
-
CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Healthcare Costs Among Patients With CML Receiving Dasatinib or Nilotinib in a Commercial and Medicare Population
This completed clinical trial analyzes healthcare costs among patients with Chronic Myeloid Leukemia treated with dasatinib or nilotinib in …
-
CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy [Phase 1]
This Phase 1 clinical trial update reports the tolerance and biologic activity of oral ciclopirox olamine in patients with relapsed or refra…
-
CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701) [Phase 1, Phase 2]
Phase 1/2 trial of a Farnesyl Protein Transferase Inhibitor in leukemia and myelodysplastic syndromes has completed, sponsored by Merck Shar…
-
CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation [EARLY_Phase 1]
An early-phase study update reporting completion of a trial using abdominal CT to predict acute graft-versus-host disease risk after allogen…
-
CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of OPB-51602 in Patients With Hematologic Malignancies [Phase 1]
Phase I trial results are reported for OPB-51602 in patients with hematologic malignancies including multiple myeloma, non-Hodgkin lymphoma,…
-
CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Safety of Zileuton (Zyflo) in Combination With Imatinib Mesylate (Gleevec) in CML. [Phase 1]
Phase 1 trial assessing the safety of combining zileuton (Zyflo) with imatinib mesylate (Gleevec) in chronic myeloid leukemia; the study was…
-
CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: Bioequivalence Study of Mesylate Imatinib Capsule in Chronic Myeloid Leukemia Body [Phase 1]
Phase 1 bioequivalence study of imatinib mesylate capsule in chronic myeloid leukemia; results were posted on 2015-05-19.
-
CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias [Phase 1]
Phase 1 study of TH-302 (evofosfamide), a hypoxia-activated prodrug, in patients with advanced leukemias has been completed, with evaluation…
-
CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Determining the Maximum Tolerated Dose of Low Dose Interferon-alpha in Conjunction With Nilotinib in Pretreated Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia Patients in Chronic Phase (CML-CP) [Phase 1]
Phase 1 trial completed to determine the maximum tolerated dose of low-dose interferon-alpha in combination with nilotinib for patients with…
-
CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Pegasys in Patients With Chronic Myeloid Leukemia (CML) [Phase 2]
A Phase 2 clinical trial evaluating Pegasys (pegylated interferon alfa-2a) in chronic myeloid leukemia was terminated, with results posted i…
-
CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants [Phase 2]
A Phase 2 clinical trial evaluating a sirolimus-tacrolimus combination following HLA-matched related peripheral blood stem cell transplantat…
-
CLINICAL_TRIALS trial_result · 2015-03-20Clinical Trial Update: Phase I/II Study of Immune Therapy After Allograft in Patients With Myeloid Hemopathy [Phase 1, Phase 2]
An update on a Phase I/II trial evaluating an immune therapy given after allogeneic transplantation in patients with myeloid hematologic dis…
-
CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: Multicenter, PhaseⅣ, Open Label Trial of Nilotinib in Adult Patients Diagnosed Philadelphia Chromosome Positive(Ph+) Chronic Myeloid Leukemia in CP/AP Intolerant to Dasatinib [Phase 4]
This is a multicenter, Phase 4 open-label trial of nilotinib in adult patients with Philadelphia chromosome–positive chronic myeloid leukemi…
-
CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Haploid Allogeneic Transplant Using the CliniMACS System [Phase 2]
A Phase 2 clinical trial evaluating haploid allogeneic transplantation using the CliniMACS System was terminated, with results posted in 201…
-
CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies [Phase 1]
A Phase 1 pilot study evaluated co-infusing ex vivo expanded cord blood cells with an unmanipulated cord blood unit in patients undergoing c…
-
CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Study to Evaluate Nilotinib in Chronic Myelogenous Leukemia (CML) Patients With SubOptimal Response [Phase 4]
This document reports the completion of a Phase 4 clinical trial evaluating nilotinib in chronic myeloid leukemia patients with suboptimal r…
-
CLINICAL_TRIALS trial_result · 2015-01-30Clinical Trial Update: A Phase I Dose Escalation Combination Study in Patients With Chronic Myelogenous Leukemia (CML) and Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)(0457-009)(TERMINATED) [Phase 1]
A Phase I dose-escalation combination study in patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblast…
-
CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: A Phase II Study of MK0457 in Patients With T315I Mutant CML and Ph+All (0457-008) [Phase 2]
Phase II trial of MK0457 in T315I-mutant chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia was term…
-
CLINICAL_TRIALS trial_result · 2015-01-15Clinical Trial Update: Homoharringtonine With Oral Gleevec in Chronic, Accelerated and Blast Phase Chronic Myeloid Leukemia (CML) [Phase 2]
A Phase 2 study evaluating the combination of homoharringtonine with oral imatinib (Gleevec) in chronic, accelerated-phase, and blast-phase …