Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Late Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 clinical trial evaluating treatment for late chronic phase chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: High-Dose Gleevec Alone or in Combination With Peg-Intron and GM-CSF in Early Phase Chronic Myelogenous Leukemia (CML) [Phase 3]
A Phase 3 study evaluated high-dose imatinib (Gleevec) given alone or in combination with pegylated interferon alfa-2b (Peg-Intron) and GM-C…
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies [Phase 2]
Phase 2 trial evaluating a conditioning regimen of fludarabine phosphate, busulfan, and anti-thymocyte globulin followed by donor peripheral…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation [Phase 2]
Phase 2 clinical trial evaluating repeat transplantation for relapsed or refractory hematologic malignancies after prior transplant; the stu…
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CLINICAL_TRIALS trial_result · 2016-04-21Clinical Trial Update: Effect of Imatinib Mesylate and the Pharmacokinetics of Acetaminophen/Paracetamol in Patients With Newly Diagnosed, Previously Untreated Chronic Myeloid Leukemia in Chronic Phase (CML-CP) [Phase 1]
Phase 1 study evaluating imatinib mesylate and the pharmacokinetics of acetaminophen in patients with newly diagnosed chronic myeloid leukem…
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Nilotinib Pre and Post Allogeneic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating nilotinib given before and after allogeneic stem cell transplantation in chronic myeloid leukemia and acute lymphob…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Metabolic Outcomes in Patients Receiving Tyrosine Kinase Inhibitor (TKI) Therapy With Dasatinib or Nilotinib
A completed clinical trial evaluating metabolic outcomes in patients with chronic myeloid leukemia treated with the tyrosine kinase inhibito…
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Safety and Efficacy of Nilotinib in Newly Diagnosed Chronic Myeloid Leukemia Patients [Phase 3]
Phase 3 study evaluating the safety and efficacy of nilotinib in newly diagnosed chronic myeloid leukemia; results were posted for this comp…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and efficacy of POL6326 for mobilization and transplant in hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Radotinib Versus Imatinib in Newly Diagnosed Philadelphia Chromosome and Chronic Myeloid Leukemia Chronic Phase Patients [Phase 3]
A Phase 3 randomized trial comparing radotinib to imatinib in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia [Phase 1]
Phase 1 study of Terameprocol (EM-1421) in leukemia was terminated; no efficacy results were reported in this update.
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: CMR Rate of Newly Diagnosed CML-CP Patients Treated With Nilotinib [Phase 4]
Phase 4 trial update reports the rate of complete molecular response (CMR) in newly diagnosed chronic myeloid leukemia patients treated with…
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: A Pharmacokinetic (PK) Study of Nilotinib in Pediatric Patients With Philadelphia Chromosome-positive (Ph+) Chronic Myelogenous Leukemia (CML) or Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 pharmacokinetic study of nilotinib in pediatric patients with Philadelphia chromosome–positive CML or ALL; study completed with resu…
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 2]
This clinical trial update reports long-term safety data for dasatinib in patients with chronic myeloid leukemia and Philadelphia chromosome…
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Therapy of Early Chronic Phase CML With Gleevec [Phase 2]
Phase 2 trial evaluating Gleevec (imatinib) in early chronic phase chronic myeloid leukemia; the study has completed.
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CLINICAL_TRIALS trial_result · 2015-12-31Clinical Trial Update: Alloreactive Haploidentical Natural Killer (NK) Cells With Busulfan and Fludarabine/ATG [Phase 2]
Phase 2 clinical trial evaluating alloreactive haploidentical natural killer cells with busulfan and fludarabine/ATG conditioning in leukemi…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: An Open-Label, Multicenter, Expanded Access Study of Oral AMN 107 in Adult Patients With Imatinib (Glivec®/Gleevec®_ - Resistant or Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase [NA]
Open-label, multicenter expanded-access study of nilotinib (AMN-107) in adults with imatinib-resistant or -intolerant chronic myeloid leukem…
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating HLA-nonidentical stem cell and natural killer cell transplantation in children under two with hematologic malignanc…
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Safety and Efficacy of Nilotinib vs. Imatinib in the Treatment of Newly Diagnosed Chinese Ph+ CML-CP Patients [Phase 3]
This Phase 3 trial compares nilotinib to imatinib as first-line therapy for Philadelphia chromosome-positive chronic myeloid leukemia in Chi…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: Nuvigil in Treatment of Cancer-Related Fatigue in Chronic Myeloid Leukemia Patients [NA]
A terminated MD Anderson clinical trial evaluated armodafinil (Nuvigil) for cancer-related fatigue in chronic myeloid leukemia patients, wit…
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: PEG Interferon Alpha 2B and Low-Dose Ara-C in Early Chronic Phase CML [Phase 1]
This is a Phase 1 study evaluating pegylated interferon alfa-2b in combination with low-dose cytarabine for early-phase chronic myeloid leuk…
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CLINICAL_TRIALS trial_result · 2015-11-16Clinical Trial Update: Randomized Phase Lll Study of Imatinib Dose Optimization vs Nilotinib in CML Patients With Suboptimal Response to Imatinib [Phase 3]
A randomized phase III trial compared imatinib dose optimization versus nilotinib in chronic myeloid leukemia patients with suboptimal respo…
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CLINICAL_TRIALS trial_result · 2015-11-13Clinical Trial Update: Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a triple regimen of vorinostat, tacrolimus, and methotrexate to prevent graft-versus-host disease after allogeneic …
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit [Phase 2]
Phase 2 clinical trial evaluating hematopoietic stem cell transplantation using a CD34-selected mismatched related donor plus one umbilical …
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Dasatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase [Phase 2]
A Phase 2 clinical trial evaluating dasatinib in patients with chronic myeloid leukemia in chronic phase; the trial status is currently unkn…