Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia (CML) [Phase 4]
A Phase 4 clinical trial comparing standard-dose versus high-dose imatinib mesylate in patients with chronic phase Philadelphia chromosome–p…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant [Phase 2]
Phase 2 trial of T-cell replete haploidentical donor hematopoietic stem cell transplantation with natural killer (NK) cell support in hemato…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological Malignancies [Phase 1, Phase 2]
Phase 1 and Phase 2 results are reported for allogeneic cytokine-induced killer (CIK) cell immunotherapy given to patients who relapsed afte…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Autologous Cytokine Induced Killer Cells (CIK) for Chronic Myeloid Leukemia (CML) Patients on Standard Drug Therapy [Phase 2]
Phase 2 trial evaluating autologous cytokine-induced killer (CIK) cells for patients with Chronic Myeloid Leukemia on standard drug therapy …
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Comparative Evaluation of Results of Allogeneic Hematopoietic Stem Cells Versus Ponatinib in CML Patients Carrying a Mutation T315I
This trial compares the outcomes of allogeneic hematopoietic stem cell transplantation versus ponatinib in chronic myeloid leukemia patients…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Study of Cemivil® (Imatinib) in Chronic Myeloid Leukemia Patients in Jordan
A clinical trial evaluating Cemivil (imatinib) for chronic myeloid leukemia in Jordan has completed.
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Evaluating True PCR-negative Rate of Frontline Dasatinib in Early Chronic Phase CML for Therapeutic Harmonization
Clinical trial update evaluating the true PCR-negative rate of frontline dasatinib in early chronic phase chronic myeloid leukemia for thera…
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Phase IV, Open-label, Multicenter Study of Dasatinib in Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients With Chronic, Low-grade Non-Hematologic Toxicity to Imatinib [Phase 4]
Phase IV open-label multicenter study evaluating dasatinib in chronic-phase chronic myeloid leukemia patients who have chronic, low-grade no…
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CLINICAL_TRIALS trial_result · 2016-11-16Clinical Trial Update: Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 Trial [Phase 4]
Phase 4 trial update showing completion of a study of oral nilotinib (AMN107) in adults with imatinib-resistant or intolerant chronic myeloi…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Discontinuation of Imatinib Mesylate in Patients With Chronic-Phase Chronic Myeloid Leukemia Previously Treated With Interferon-Alpha
The clinical trial evaluating discontinuation of imatinib mesylate in patients with chronic-phase chronic myeloid leukemia previously treate…
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Glivec in Pediatric Chronic Myeloid Leukemia (CML) [Phase 4]
This clinical trial update notes the Phase 4 study of imatinib (Glivec) for pediatric chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating dasatinib in combination with chemotherapy for newly diagnosed acute lymphoblastic leukemia, including B…
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Evaluating the Safety of Zileuton (Zyflo®) in Combination With Dasatinib (Sprycel®) in Chronic Myelogenous Leukemia [Phase 1]
Phase 1 trial evaluating the safety of combining zileuton with dasatinib in chronic myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Patient Reported Outcomes in Chronic Myeloid Leukemia
This update notes the completion of a clinical trial evaluating patient-reported outcomes in Chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Pioglityazone and Imatinib for CML Patients [Phase 2]
Phase 2 trial examining pioglitazone in combination with imatinib for chronic myeloid leukemia has completed; no results are provided in the…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: Population Pharmacokinetics of Imatinib in CML Patients in Iran
Clinical trial update on the population pharmacokinetics of imatinib in chronic myeloid leukemia patients in Iran. The study is terminated.
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CLINICAL_TRIALS trial_result · 2016-08-22Clinical Trial Update: OPTIM DASATINIB (Optimized Tyrosine Kinase Inhibitors Monotherapy) [Phase 2]
A Phase 2 trial of dasatinib as optimized monotherapy for BCR-ABL positive chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Umbilical Cord Blood Transplant for Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating umbilical cord blood transplantation for hematologic malignancies has completed enrollment and reporting.
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Nilotinib Versus Standard Imatinib (400/600 mg Every Day (QD)) Comparing the Kinetics of Complete Molecular Response for Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) Pts With Evidence of Persistent Leukemia by Real-time Quantitative Polymerase Chain Reaction (RQ-PCR) [Phase 3]
Phase 3 trial comparing nilotinib versus standard imatinib in chronic-phase chronic myeloid leukemia; study evaluated kinetics of complete m…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous Leukemia [Phase 1]
This is a Phase 1 ascending-dose study of KW-2449 in patients with acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2016-08-05Clinical Trial Update: Expanded Access Study With Peginterferon Alfa-2a (Pegasys) in Participants With Chronic Myelogenous Leukemia (CML) [Phase 3]
An update on a Phase 3 expanded-access study of peginterferon alfa-2a (Pegasys) for chronic myeloid leukemia, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Non-interventional Treatment Patterns Study in Chronic Phase Chronic Myelogenous Leukemia (CP-CML)
This entry notes the completion of a non-interventional treatment-patterns study in chronic phase chronic myeloid leukemia, sponsored by Bri…
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: Homoharringtonine Compared With Hydroxyurea for Chronic Myelogenous Leukemia That Has Not Responded to Interferon Alfa [Phase 3]
A Phase 3 trial comparing homoharringtonine with hydroxyurea for chronic myeloid leukemia that has not responded to interferon alfa has been…
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Chemotherapy for Leukemia [Phase 1, Phase 2]
A completed Phase 1/2 safety study evaluating CLT-008 (human myeloid progenitor cells) in patients with various leukemias after chemotherapy…
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)
A Stanford-sponsored clinical trial evaluating allogeneic transplantation for acute and chronic leukemias has been terminated.