Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis [Phase 2]
A Phase 2 trial (ABBA CORD) evaluating donor-derived cord blood T cells with abatacept for prophylaxis of acute graft-versus-host disease in…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Study of Olverembatinib (HQP1351) in Patients With CP-CML [Phase 3]
This report notes a Phase 3 clinical trial evaluating Olverembatinib (HQP1351) in patients with chronic-phase chronic myeloid leukemia, curr…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP
The document describes a clinical trial evaluating the efficacy and safety of combining third-generation tyrosine kinase inhibitors with aza…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Asciminib Used in Consolidation With Imatinib vs. Imatinib to Achieve TFR in CP-CML [Phase 3]
A Phase 3 study evaluating whether adding asciminib to imatinib improves achievement of treatment-free remission in chronic-phase chronic my…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
Phase 1 study update for Orca-T in recipients undergoing allogeneic transplantation for hematologic malignancies; the trial is currently act…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial [Phase 2]
Phase 2 trial evaluating fecal microbiota transplantation before allogeneic stem cell transplant; recruitment is ongoing across multiple hem…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Interest of PHARMaceutical Conciliation to Understand Drug Interactions, Phytotherapy, and Targeted Therapies in Chronic Myeloid Leukemia [NA]
A recruiting clinical trial at Centre Hospitalier Universitaire de Saint-Étienne investigating drug interactions, phytotherapy, and targeted…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I Mutation [Phase 2]
Phase 2 clinical trial update for patients with chronic myeloid leukemia or acute lymphoblastic leukemia who failed prior TKIs or have the T…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia
A clinical trial is currently recruiting to compare the efficacy and safety of Carcemia, a generic imatinib, with Glivec in the real-world m…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Venetoclax After TKI to Target Persisting Stem Cells in CML [Phase 2]
Phase 2 clinical trial evaluating venetoclax after tyrosine kinase inhibitors to eradicate persisting stem cells in chronic myeloid leukemia…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Evaluation of CD47, "Do Not Eat Me" Signal Expression in Chronic Myeloid Leukemia
Clinical trial update investigating expression of the CD47 'do not eat me' signal in chronic myeloid leukemia.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: TGRX-678 Chinese Phase I in Chronic Myelogenous Leukemia (CML) Patients [Phase 1]
Phase 1 clinical trial update for TGRX-678 in Chinese patients with chronic myeloid leukemia; trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: TGRX-678 Chinese Phase II in Chronic Myelogenous Leukemia (CML) Patients [Phase 2]
A Phase II clinical trial of TGRX-678 in Chinese patients with chronic myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Condition Vasoregulation Function Endothelium in Patients With CML Getting TKI II Generation Bosutinib
A clinical trial update notes that a study evaluating vasoregulation function of the endothelium in patients with chronic myeloid leukemia t…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Interaction Between Gut Microbiota and TKIs in Defining the Clinical Outcomes of Patients With CML
A ClinicalTrials.gov entry reports an ongoing study investigating how gut microbiota interacts with tyrosine kinase inhibitors to influence …
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients with Chronic Myeloid Leukemia [Phase 2]
This update discusses a Phase 2 trial evaluating the efficacy and safety of withdrawing tyrosine kinase inhibitors after a two-step dose red…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: A Clinical Trial to Evaluate the Safety and Tolerability of TQB3911 Tablets in Patients With BCR::ABL Fusion Gene Positive Leukemia [Phase 1]
A Phase 1 trial to evaluate the safety and tolerability of TQB3911 tablets in patients with BCR-ABL positive chronic myeloid leukemia, not y…
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Efficacy and Safety of Dose Redution of Radotinib as a First Line Treament in Ph+ CML
This clinical trial update evaluates dose reduction of Radotinib as a first-line treatment for Philadelphia chromosome-positive chronic myel…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: A Phase 3 Study for the Efficacy and Safety of Radotinib in CP-CML Patients With Failure or Intolerance to Previous TKIs [Phase 3]
This entry describes a Phase 3 clinical trial evaluating radotinib for chronic myeloid leukemia in chronic phase patients who failed or were…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Long-term Risk of Second Primary Malignancies for Chronic Myeloid Leukaemia in the French Imatinib-based SPIRIT Trial
This update discusses the long-term risk of a second primary malignancy in patients with chronic myeloid leukemia treated with imatinib in t…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: Value of Biological Age, in Addition to Individual Frailty, for Personalising the Management of Cancer Treated with Targeted Therapy [NA]
Clinical trial evaluating how biological age and frailty influence management of chronic myeloid leukemia treated with targeted therapy; cur…
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: CML Pediatric ITK Response According to Molecular Identification at Diagnosis
A pediatric chronic myeloid leukemia trial evaluating ITK response according to molecular identification at diagnosis is currently recruitin…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen [Phase 2]
Phase 2 clinical trial evaluating sorafenib as relapse prophylaxis after hematopoietic cell transplantation using the PTBCy regimen; the stu…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Study of HS-10382 Combination in Patients With Chronic Myeloid Leukemia (CML) [Phase 1]
A Phase 1 trial of HS-10382 in combination therapy for chronic myeloid leukemia is not yet recruiting.