Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Personalized NK Cell Therapy in CBT [Phase 2]
A Phase 2 trial from MD Anderson is evaluating personalized NK cell therapy across several hematologic cancers. The study is currently recru…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating asciminib monotherapy with dose escalation for first- and second-line chronic myeloid leukemia is active but not re…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: What is the Impact of TKI on Thyroid Function in CML Patients?
A clinical trial is investigating whether tyrosine kinase inhibitors used for chronic myeloid leukemia affect thyroid function. The study is…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies [EARLY_Phase 1]
An early-phase trial evaluating Darzalex Faspro (daratumumab and hyaluronidase-fihj) given before desensitization and allogeneic stem cell t…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: 2nd or 3rd TKI-stop After 2 Years Nilotinib Pre-treatment in CML-patients [Phase 2]
A Phase 2 clinical trial (sponsored by European LeukemiaNet) is evaluating stopping nilotinib after two years in chronic myeloid leukemia pa…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia [Phase 1, Phase 2]
An ongoing Phase 1/2 pediatric trial evaluating bosutinib for Philadelphia chromosome-positive chronic myeloid leukemia in children, includi…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients [Phase 1]
Phase 1 trial evaluating Itacitinib with high-dose posttransplantation cyclophosphamide in older patients. The study is currently ACTIVE_NOT…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the dose and safety of Asciminib in pediatric patients with Philadelphia chromosome-positive chroni…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Quality of Life and Care Organization of Patients With Chronic Myeloid Leukemia in the Lombardy Hematology Network
An ongoing clinical trial in Lombardy evaluating quality of life and the organization of care for patients with chronic myeloid leukemia; th…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Cord Blood Transplant in Adults With Blood Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant in adults with blood cancers is currently recruiting. Conditions include acute myeloid leukem…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Identification of BCR::ABL1 Mutations by Digital PCR in CML [NA]
A clinical trial update describes using digital PCR to identify BCR-ABL1 mutations in chronic myeloid leukemia. The study is currently not r…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Improving Treatment Outcomes in Chronic Myeloid Leukaemia Patients Using Imatinib and Artesunate Combination Therapy [Phase 2]
Phase 2 clinical trial evaluating the combination of imatinib and artesunate for chronic myeloid leukemia. The study is currently active but…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: A Study of Real-world Treatment and Burden of Chronic Myeloid Leukemia Patients in Japan
A completed real-world study assessing treatment patterns and burden among chronic myeloid leukemia patients in Japan, sponsored by Novartis…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Expression Pattern and Possible Clinical Significance of CD81 In Myeloid Leukemia
This clinical trial update investigates CD81 expression in acute myeloid leukemia and chronic myeloid leukemia and explores its potential cl…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes [Phase 2]
Phase 2 trial update evaluating the infusion of expanded cord blood cells in addition to a single cord blood transplant for patients with ac…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation [Phase 2]
This clinical trial update describes a Phase 2 study evaluating TCRγδ T cells and memory T cells with selective use of blinatumomab as part …
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia
A clinical trial is recruiting to investigate whether tyrosine kinase inhibitors used to treat Chronic Myeloid Leukemia are associated with …
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Protocol Number: HJKC3-0003. Treatment Free Remission After Asciminib Based Therapy in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation [Phase 2]
A Phase 2 trial evaluating treatment-free remission after asciminib-based therapy in chronic phase chronic myeloid leukemia patients who rel…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) Therapy
A real-world patient registry study to describe experiences and clinical outcomes of chronic myeloid leukemia patients in the chronic phase …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Administration of Donor T Cells With the Caspase-9 Suicide Gene [Phase 1]
A Phase 1 trial evaluating donor T cells engineered with a caspase-9 suicide gene to enable controlled safety in hematologic diseases.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML [Phase 2]
Phase 2 PEARL trial evaluating asciminib for early treatment of chronic myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Allo HSCT Using RIC and PTCy for Hematological Diseases [Phase 2]
Phase 2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning and post-transplan…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: ELVN-001 for the Treatment of Chronic Myeloid Leukemia With and Without T315I Mutation in Japanese Participants [Phase 1]
A Phase 1 trial of ELVN-001 in Japanese participants with chronic myeloid leukemia (with or without the T315I mutation) is currently recruit…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 clinical trial evaluating intensity-modulated total marrow irradiation in fully matched and partially matched allogeneic transplan…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders [Phase 2]
Phase 2 clinical trial evaluating myeloablative allogeneic hematopoietic stem cell transplantation from related or unrelated donors for a br…