Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-12-30Clinical Trial Update: Rituximab and Fludarabine Followed by CAMPATH-1H in Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial evaluating Rituximab and Fludarabine followed by alemtuzumab (CAMPATH-1H) in chronic lymphocytic leukemia and small lymphocyti…
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CLINICAL_TRIALS trial_result · 2010-12-20Clinical Trial Update: A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-263 (Navitoclax). [Phase 1]
Phase 1 study evaluating how ketoconazole affects the metabolism of navitoclax (ABT-263) in patients with lymphoma, chronic lymphocytic leuk…
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CLINICAL_TRIALS research · 2010-10-29Clinical Trial Update: Host Dendritic Cells in Allograft Patients [Phase 1]
Phase 1 clinical trial update from Icahn School of Medicine at Mount Sinai evaluating host dendritic cells in allograft patients for relapse…
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FDA approval · 2010-10-12FDA Approved: REVLIMID — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for REVLIMID (lenalidomide) submitted by Celgene Corporation.
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CLINICAL_TRIALS trial_result · 2010-10-07Clinical Trial Update: Assess the Oral Bioavailability of New ABT-263 Formulations [Phase 1]
Phase 1 pharmacokinetic study assessing oral bioavailability of new ABT-263 formulations.
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CLINICAL_TRIALS trial_result · 2010-09-22Clinical Trial Update: Chemotherapy in Treating Patients With Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
A Phase 1/2 chemotherapy study for chronic lymphocytic leukemia has completed, according to the clinical trial update.
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CLINICAL_TRIALS trial_result · 2010-09-15Clinical Trial Update: High-Dose Chemotherapy Followed by Total-Body Irradiation and Peripheral Stem Cell Transplantation in Treating Patients With Chronic Lymphocytic Leukemia [Phase 1]
This Phase 1 clinical trial evaluates high-dose chemotherapy with total-body irradiation followed by peripheral stem cell transplantation in…
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CLINICAL_TRIALS trial_result · 2010-09-14Clinical Trial Update: Combined Treatment With Fresh Frozen Plasma and Rituximab (Mabthera) in Patients With Advanced Refractory Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial investigates combining fresh frozen plasma with Rituximab (Mabthera) in patients with advanced refractory chronic l…
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CLINICAL_TRIALS trial_result · 2010-09-10Clinical Trial Update: Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2, multi-center trial evaluating the combination of lenalidomide (Revlimid) and rituximab as first-line therapy for chronic lymphocyti…
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CLINICAL_TRIALS trial_result · 2010-08-13Clinical Trial Update: Phase 2 Safety and Efficacy Study of AT-101 in Combination With Rituximab in Patients With Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating AT-101 in combination with Rituximab for chronic lymphocytic leukemia has completed, assessing safety an…
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CLINICAL_TRIALS trial_result · 2010-07-30Clinical Trial Update: Donor Natural Killer Cell Infusion, Rituximab, Aldesleukin, and Chemotherapy in Treating Patients With Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating donor natural killer cell infusion with Rituximab, Aldesleukin, and chemotherapy in relapsed non-Hodgkin lymphoma…
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: BL22 Immunotoxin in Treating Patients With Refractory Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, or Non-Hodgkin's Lymphoma [Phase 1]
Phase 1 trial of BL22 immunotoxin in patients with refractory chronic lymphocytic leukemia, prolymphocytic leukemia, and non-Hodgkin lymphom…
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CLINICAL_TRIALS trial_result · 2010-06-02Clinical Trial Update: The Humanized Monoclonal Antibody Milatuzumab for Refractory Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
A clinical trial update on milatuzumab for refractory chronic lymphocytic leukemia across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2010-05-05Clinical Trial Update: Study of Immune Response Modifier in the Treatment of Hematologic Malignancies [Phase 2]
Phase 2 trial of an immune response modifier in hematologic malignancies has terminated with posted results.
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CLINICAL_TRIALS withdrawal · 2010-04-22Clinical Trial Update: Study of MDX-1411 in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma [Phase 1]
A Phase 1 study of MDX-1411 for relapsed/refractory chronic lymphocytic leukemia or mantle cell lymphoma has been withdrawn from the trial p…
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CLINICAL_TRIALS trial_result · 2010-03-31Clinical Trial Update: Trial of Forodesine in Patients With Relapsed B-cell Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 clinical trial of forodesine in relapsed B-cell chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2010-03-08Clinical Trial Update: Phase 1, Dose-Escalation, Pharmacodynamic Study of IV CNF1010 in ZAP-70 Positive CLL [Phase 1]
Phase 1 dose-escalation pharmacodynamic study of CNF1010 in ZAP-70 positive chronic lymphocytic leukemia; the study is terminated.
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FDA approval · 2010-02-26FDA Approved: TREANDA — Supplemental Application (Cephalon, LLC)
The FDA approved a supplemental application for TREANDA (bendamustine hydrochloride) from Cephalon, LLC, enabling revisions to its labeling …
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CLINICAL_TRIALS withdrawal · 2010-02-26Clinical Trial Update: Study Assessing the Safety and Efficacy of ABT-263 in Subjects With B-cell Chronic Lymphocytic Leukemia (CLL) Who Have Failed at Least One Prior Fludarabine-containing Regimen [Phase 2]
The Phase 2 study of ABT-263 (navitoclax) in B-cell chronic lymphocytic leukemia that failed prior regimens has been withdrawn.
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CLINICAL_TRIALS trial_result · 2010-02-24Clinical Trial Update: Bryostatin + Fludarabine in Treating Patients With Chronic Lymphocytic Leukemia or Relapsed Indolent Non-Hodgkin's Lymphoma [Phase 1]
Phase 1 trial evaluating the combination of bryostatin and fludarabine in patients with chronic lymphocytic leukemia or relapsed indolent no…
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CLINICAL_TRIALS trial_result · 2010-02-23Clinical Trial Update: High-dose Methylprednisolone and Rituximab in High Risk B-CLL [Phase 2]
Phase 2 trial evaluating high-dose methylprednisolone with rituximab in high-risk chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2009-12-16Clinical Trial Update: A Single-arm Phase II Study of Alemtuzumab in Combination With High-dose Methylprednisolone in CLL Patients With p53 Deletion [Phase 2]
This report summarizes the completion of a single-arm Phase II study evaluating alemtuzumab in combination with high-dose methylprednisolone…
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CLINICAL_TRIALS research · 2009-11-13Clinical Trial Update: Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
Phase I/II study of Genasense (oblimersen sodium) in chronic lymphocytic leukemia sponsored by Genta Incorporated has completed.
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FDA approval · 2009-10-16FDA Approved: RITUXAN — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for Rituxan (rituximab) from Genentech.
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CLINICAL_TRIALS trial_result · 2009-08-18Clinical Trial Update: T-cell and B-cell Depletion in Allogeneic Peripheral Blood Stem Cell Transplantation [Phase 3]
A Phase 3 trial investigating T-cell and B-cell depletion in allogeneic peripheral blood stem cell transplantation has been terminated.