Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring [Phase 1]
Phase 1 rollover study by Janssen Research & Development to continue study treatment and ongoing safety monitoring in patients with acute my…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003) [Phase 2]
Phase 2 trial update on the efficacy and safety of Nemtabrutinib (MK-1026) in hematologic malignancies, including Waldenström macroglobuline…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL [Phase 2]
A Phase 2 clinical trial at Massachusetts General Hospital is evaluating venetoclax and obinutuzumab with or without acalabrutinib in relaps…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Lenalidomide, Ibrutinib, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma That Is Metastatic or Cannot Be Removed by Surgery [Phase 1]
A Phase 1 clinical trial update investigating a combination of lenalidomide, ibrutinib, and rituximab for relapsed or refractory chronic lym…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial update for customizing ibrutinib treatment regimens in previously untreated chronic lymphocytic leukemia and small lymphocytic…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies [Phase 1, Phase 2]
AstraZeneca is evaluating AZD0486 as a monotherapy or in combination with other anticancer agents for mature B-cell malignancies in Phase 1/…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study on Treatment Outcome Patterns for Patients With CLL After Discontinuation of BTK Inhibitors [Phase 2]
A Phase 2 clinical trial update examining treatment outcome patterns for patients with chronic lymphocytic leukemia or small lymphocytic lym…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension Study of PCI-32765 (Ibrutinib) [Phase 3]
Phase 3 long-term extension study of ibrutinib (PCI-32765) in chronic lymphocytic leukemia/small lymphocytic lymphoma and other B-cell malig…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies [Phase 1, Phase 2]
This document provides an update on a Phase 1/2 study of NX-5948 in combination with other agents for adults with B-cell malignancies. The t…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain
This is a clinical trial update announcing a study to assess changes in functioning and health-related quality of life in adults with chroni…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating the effectiveness of Mirdametinib in relapsed/refractory chronic lymphocytic leukemia and small lymph…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen
Prospective collection, storage, and reporting of data on patients undergoing hematopoietic stem cell transplantation using a standard prepa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia
A recruiting clinical trial sponsored by Janssen Cilag S.A.S. is evaluating whether an individual physical activity intervention improves he…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011) [Phase 3]
Phase 3 trial evaluating Nemtabrutinib (MK-1026) versus investigator's choice of ibrutinib or acalabrutinib in first-line chronic lymphocyti…
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EMA withdrawal · 2026-04-09EMA Withdrawn: Copiktra (duvelisib) — Secura Bio Limited
The European Medicines Agency has withdrawn the marketing authorization for Copiktra (duvelisib) from Secura Bio Limited; the drug for chron…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL) [Phase 3]
A Phase 3 clinical trial update evaluating the risk of tumor lysis syndrome in adults with previously untreated chronic lymphocytic leukemia…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial [Phase 2]
The PROTECT CLL trial is a Phase 2 study evaluating vaccination with PCV20 and PPSV23 in patients with CLL-associated immunodeficiency; the …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients [NA]
This study examines how structured exercise affects immune phenotype in patients with indolent non-Hodgkin lymphoma and chronic lymphocytic …
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T [Phase 1]
This clinical trial update reports long-term follow-up results from a Phase 1 study of CLBR001 CAR-T cells in relapsed/refractory B-cell lym…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL [Phase 3]
A Phase 3 clinical trial is planned to compare NX-5948 against Pirtobrutinib in relapsed/refractory chronic lymphocytic leukemia and small l…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Trial of "Armored" CAR T Cells Targeting CD19 For Patients With Relapsed CD19+ Hematologic Malignancies [Phase 1]
Phase 1 study evaluating armored CD19-targeted CAR T cells in patients with relapsed or refractory chronic lymphocytic leukemia; status is a…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Ibrutinib as an Immune Modulating Agent for Patients With Asymptomatic, High-risk CLL/SLL Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial update evaluating ibrutinib as an immune-modulating agent for asymptomatic, high-risk chronic lymphocytic leukemia or small ly…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study [NA]
Completed clinical trial evaluating a geriatric optimization plan to improve survival in older adults undergoing allogeneic hematopoietic ce…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study on Limiting Treatment Time With Acalabrutinib Combined With Obinutuzumab in People With CLL or SLL [Phase 2]
This update covers a Phase 2 trial evaluating shortening treatment duration with acalabrutinib in combination with obinutuzumab for chronic …
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: A Study of Venetoclax and Rituximab/Hyaluronidase Human in Relapsed/Refractory CLL [Phase 2]
A Phase 2 clinical trial evaluating venetoclax in combination with rituximab and hyaluronidase for relapsed/refractory chronic lymphocytic l…