Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-03-18Clinical Trial Update: A Study to Determine Dose, Safety, and Efficacy of Durvalumab as Monotherapy and in Combination Therapy in Subjects With Lymphoma or Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated durvalumab as monotherapy and in combination therapy for lymphoma and chronic lymphocytic leukemia, and…
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: A Study of Ibrutinib in Combination With Bendamustine and Rituximab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 3]
Phase 3 trial evaluating ibrutinib with bendamustine and rituximab in relapsed/refractory CLL or SLL has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-28Clinical Trial Update: Safety and Efficacy of the Combination of Tirabrutinib and Entospletinib With and Without Obinutuzumab in Adults With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating tirabrutinib plus entospletinib with or without obinutuzumab in adults with chronic lymphocytic leukemia; results p…
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CLINICAL_TRIALS trial_result · 2020-02-27Clinical Trial Update: A Study of Different Doses of Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL) [Phase 2, Phase 3]
A clinical trial evaluating different doses of ibrutinib in chronic lymphocytic leukemia has completed Phase 2 and Phase 3 arms with results…
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CLINICAL_TRIALS trial_result · 2020-02-24Clinical Trial Update: Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL [Phase 1, Phase 2]
A pilot study evaluating the Btk inhibitor PCI-32765 (ibrutinib) effects on leukemia cell kinetics and trafficking in CLL/SLL using heavy wa…
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CLINICAL_TRIALS trial_result · 2020-02-20Clinical Trial Update: Fludarabine or Observation in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial evaluating fludarabine versus observation in early-stage chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Lenalidomide in Chronic Lymphocytic Leukemia (CLL) Patients With Residual Disease [Phase 2]
Phase 2 clinical trial update of lenalidomide in chronic lymphocytic leukemia patients with residual disease has completed results and poste…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Allogeneic Stem Cell Transplant for CLL [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation for chronic lymphocytic leukemia and related diseas…
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CLINICAL_TRIALS trial_result · 2020-01-30Clinical Trial Update: Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi [Phase 2]
Phase 2 study evaluating safety and preliminary efficacy of tafasitamab with idelalisib or venetoclax in relapsed/refractory CLL/SLL patient…
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL) [Phase 2]
A Phase 2 trial on nonmyeloablative stem cell transplantation for chronic lymphocytic leukemia has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: Rituximab Versus Observation as Maintenance Therapy in Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) [Phase 3]
Phase 3 trial comparing rituximab maintenance therapy to observation in chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2019-12-30Clinical Trial Update: Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial evaluating three regimens for older patients with previously untreated chronic lymphocytic leukemia: Rituximab plus Bendamusti…
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CLINICAL_TRIALS trial_result · 2019-12-23Clinical Trial Update: Immunotherapy With CD22 CAR T-cells for B-Cell Lymphoma, ALL and CLL [Phase 1, Phase 2]
Clinical trial update on CD22 CAR T-cells for B-cell lymphoma, acute lymphoblastic leukemia, and chronic lymphocytic leukemia across Phase 1…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults [Phase 2]
Phase 2 trial investigating an immunosuppressive regimen followed by blood cell transplant for treating blood cancers in older adults; compl…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Combination Study of IPH2201 (Monalizumab) With Ibrutinib in Relapsed, Refractory or Previously Untreated CLL [Phase 1, Phase 2]
A two-phase early-stage trial evaluated IPH2201 (monalizumab) in combination with ibrutinib for chronic lymphocytic leukemia; the study is t…
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: Rituximab in Pretreated Elderly or Unfit B-CLL Patients [Phase 2]
Phase 2 clinical trial evaluating rituximab in pretreated elderly or unfit patients with B-cell chronic lymphocytic leukemia has completed w…
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CLINICAL_TRIALS trial_result · 2019-12-09Clinical Trial Update: Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant [Phase 2]
Phase 2 trial investigating sirolimus, cyclosporine, and mycophenolate mofetil to prevent graft-versus-host disease in patients with blood c…
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FDA approval · 2019-11-26FDA Approved: CAMPATH — Supplemental Application (Genzyme Corporation)
FDA approved a supplemental application for CAMPATH (alemtuzumab) filed by Genzyme Corporation to update the product labeling.
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: A Study Evaluating the Efficacy of Obinutuzumab and Bendamustine Treatment in Participants With Refractory or Relapsed Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating obinutuzumab with bendamustine in relapsed/refractory chronic lymphocytic leukemia has completed with results poste…
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CLINICAL_TRIALS trial_result · 2019-11-22Clinical Trial Update: Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies [Phase 2]
Phase 2 clinical trial assessing donor atorvastatin to prevent severe acute GVHD after nonmyeloablative peripheral blood stem cell transplan…
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FDA approval · 2019-11-21FDA Approved: TREANDA — Supplemental Application (Cephalon, LLC)
The FDA approved a supplemental application for TREANDA (bendamustine hydrochloride) submitted by Cephalon, LLC.
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FDA approval · 2019-10-29FDA Approved: CAMPATH — Supplemental Application (Genzyme Corporation)
FDA approved a supplemental application for CAMPATH (alemtuzumab) submitted by Genzyme Corporation. The approval updates the labeling/indica…
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating ex vivo-activated autologous lymph node lymphocytes in patients with chronic lymphocytic leukemia; study s…
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CLINICAL_TRIALS trial_result · 2019-10-24Clinical Trial Update: Subcutaneous Alemtuzumab Combined With Oral Dexamethasone, Followed by Alemtuzumab Maintenance or Allo-SCT in CLL With 17p- or Refractory to Fludarabine [Phase 2]
Phase 2 clinical trial evaluating subcutaneous alemtuzumab with oral dexamethasone followed by alemtuzumab maintenance or allo-SCT in CLL wi…
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CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia [Phase 2]
Phase 2 clinical trial assessing management of platelet transfusion therapy in patients with blood cancers or treatment-induced thrombocytop…