Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: Activity and Safety of Front-line Venetoclax and Rituximab in Young and Fit Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial update on frontline venetoclax and rituximab in young, fit patients with chronic lymphocytic leukemia, reporting activity and …
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies [Phase 2]
A Phase 2 clinical trial evaluating a COVID-19 vaccine booster dosing in patients with hematologic malignancies has completed enrollment and…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL [Phase 3]
Phase 3 trial comparing Zanubrutinib with Bendamustine plus Rituximab in previously untreated chronic lymphocytic leukemia or small lymphocy…
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: A Study of Orelabrutinib in CLL/SLL Patients Who Are Slowly Responding to Ibrutinib [Phase 2]
Phase 2 trial assessing orelabrutinib in CLL/SLL patients with slow response to ibrutinib is ongoing; current status is unknown.
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Clinical Study With Ibrutinib and Venetoclax for Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical study evaluating the combination of ibrutinib and venetoclax in patients with relapsed/refractory chronic lymphocytic leuke…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Lymph Node Microenvironment Modifications in Patients With CLL Treated With Venetoclax-based Regimens [Phase 4]
Phase 4 clinical trial updating lymph node microenvironment changes in chronic lymphocytic leukemia patients treated with venetoclax-based r…
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CLINICAL_TRIALS trial_result · 2023-09-25Clinical Trial Update: Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating the combination of ibrutinib and a PD-1 blockade in high-risk chronic lymphocytic leukemia has been terminated, wit…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Allo HSCT Using RIC for Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for various hematologic dise…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor [Phase 2]
Phase II trial evaluating safety and efficacy of subcutaneous plerixafor in related donors of peripheral blood stem cells for various hemato…
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: A Study of Obinutuzumab(GA101) in Combination With High-Dose Methylprednisolone(HDMP) in Chronic Lymphocytic Leukemia(CLL) Patients (GA101 & HDMP) [Phase 1, Phase 2]
Phase 1/2 trial assessing obinutuzumab with high-dose methylprednisolone in chronic lymphocytic leukemia patients.
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 3]
Phase 3 trial comparing ibrutinib plus rituximab versus FCR in untreated chronic lymphocytic leukemia or small lymphocytic lymphoma; status …
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 3]
This Phase 3 trial compares ibrutinib plus rituximab against fludarabine phosphate, cyclophosphamide, and rituximab in previously untreated …
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Entospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma [Phase 1, Phase 2]
Clinical trial updating on the use of entospletinib with obinutuzumab in relapsed CLL/SLL or NHL; Phase 1/2 study status completed with resu…
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: A Phase II Study of AT7519M, a CDK Inhibitor, in Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia [Phase 2]
Phase II study evaluating AT7519M, a CDK inhibitor, in relapsed/refractory Chronic Lymphocytic Leukemia has completed.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: A Study of Zanubrutinib (BGB-3111) Versus Ibrutinib in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 study comparing zanubrutinib to ibrutinib in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma has com…
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: Autologous Cells Derived Anti-CD19 CAR-Engineered T Cells With Concurrent BTK Inhibitor for B Cell Lymphoma [Phase 3]
Phase 3 trial investigating autologous anti-CD19 CAR-T cells given with a BTK inhibitor for B cell lymphomas, with an unspecified status.
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax [Phase 2]
A Phase 2 trial evaluating ublituximab plus umbralisib in chronic lymphocytic leukemia patients already treated with BTK inhibitors was term…
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CLINICAL_TRIALS trial_result · 2023-07-13Clinical Trial Update: Phase I/II, FIH, Dose Escalation Trial of TL-895 and Expansion of TL-895 Monotherapy and Combination Therapy With Navtemadlin in Tx-Naïve and R/R CLL/SLL Subjects [Phase 1, Phase 2]
Phase I/II trial update for TL-895 with navtemadlin in treatment-naïve and relapsed/refractory B cell malignancies, including CLL/SLL and re…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL [Phase 3]
A Phase 3 clinical trial compares acalabrutinib to investigator's choice of idelalisib plus rituximab or bendamustine plus rituximab in rela…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioning [Phase 2]
Phase 2 trial update on allogeneic transplantation using timed sequential busulfan and fludarabine conditioning for various hematologic mali…
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Bendamustine and Rituximab Induction Therapy and Maintenance Rituximab and Lenalidomide in Previously Untreated CLL/SLL [Phase 2]
Phase 2 trial evaluating bendamustine/rituximab induction followed by maintenance rituximab and lenalidomide in previously untreated CLL/SLL…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Ublituximab in Combination With Umbralisib for Participants Previously Enrolled in Protocol UTX-TGR-304 [Phase 2]
Phase 2 study evaluating ublituximab plus umbralisib in participants previously enrolled in a related protocol; the trial is terminated with…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Theophylline in Treating Patients With In Situ, Stage I, or Stage II Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial updating the use of theophylline to treat chronic lymphocytic leukemia in situ, stage I, or stage II.
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Fludarabine With or Without Cyclophosphamide in Treating Patients With Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial assessing fludarabine with or without cyclophosphamide in chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Umbralisib Plus Ublituximab (U2) in Progressive CLL After Novel Therapy [Phase 2]
Phase 2 trial of Umbralisib plus Ublituximab (U2) in progressive chronic lymphocytic leukemia after novel therapy was terminated; results po…