Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Study to Assess Safety, Tolerability and Efficacy of MB-106 in Patients With Relapsed or Refractory B-Cell NHL or CLL [Phase 1, Phase 2]
Mustang Bio's MB-106 study in relapsed or refractory B-cell lymphomas and chronic lymphocytic leukemia has been terminated, covering Phase 1…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Long-term Follow-up Study in Patients Previously Treated With a Mustang Bio CAR-T Cell Investigational Product.
A long-term follow-up update on patients previously treated with Mustang Bio's CAR-T cell investigational product; the trial has been termin…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Study of TG-1701, an Irreversible Bruton's Tyrosine Kinase Inhibitor, in Patients With B-Cell Malignancies [Phase 1]
Clinical Trial Update reports the termination of a Phase 1 study of TG-1701 in B-cell malignancies.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab [Phase 2]
Phase 2 trial evaluating letermovir for prevention of cytomegalovirus reactivation in patients with hematologic malignancies treated with al…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma [Phase 1, Phase 2]
MS-553 trial in relapsed/refractory B-cell lymphomas was terminated after Phase 1/2 studies.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Study of LOXO-305 in Chinese Participants With Blood Cancer (Including Lymphoma and Chronic Leukemia) [Phase 2]
Phase 2 clinical trial update on LOXO-305 (pirtobrutinib) in Chinese participants with B-cell malignancies, with results posted on July 16, …
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamide [Phase 2]
Phase 2 haploidentical stem cell transplantation trial using post-transplant cyclophosphamide was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Venetoclax With High-dose Ibrutinib for CLL Progressing on Single Agent Ibrutinib [Phase 1]
A Phase 1 clinical trial evaluating the combination of venetoclax with high-dose ibrutinib in chronic lymphocytic leukemia and small lymphoc…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Evaluate the Efficacy and Safety of TGR-1202 in Participants With Chronic Lymphocytic Leukemia Who Are Intolerant to Prior Therapy [Phase 2]
Phase 2 clinical trial update for TGR-1202 in patients with chronic lymphocytic leukemia intolerant to prior therapy; the study was terminat…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic Leukemia [Phase 2]
A phase 2 trial evaluating acalabrutinib for relapsed or refractory autoimmune hemolytic anemia in patients with chronic lymphocytic leukemi…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL. [Phase 3]
A Phase 3 global trial evaluating Lisaftoclax (APG-2575) in combination with acalabrutinib versus immunochemotherapy for newly diagnosed chr…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: A Study to Assess Safety of ImbruvicaTM in Indian Participants With Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy or Chronic Lymphocytic Leukemia With 17p Deletion [Phase 4]
Phase 4 safety study of ibrutinib (Imbruvica) in Indian participants with chronic lymphocytic leukemia or mantle cell lymphoma who have rece…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Sequential Regimen of Bendamustine-Debulking Followed by CAL-101 and GA101-Induction and -Maintenance in CLL (CLL2-BCG) [Phase 2]
Phase 2 trial in chronic lymphocytic leukemia evaluating a sequential regimen of bendamustine debulking followed by CAL-101 (idelalisib) and…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Biological and Clinical Efficacy of Shingrix in Patients With CLL [NA]
Registry entry describing a trial to assess the biological and clinical efficacy of Shingrix in patients with chronic lymphocytic leukemia a…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Ublituximab + TGR-1202 Compared to Obinutuzumab + Chlorambucil in Participants With Untreated and Previously Treated Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial comparing Ublituximab + TGR-1202 versus Obinutuzumab + Chlorambucil in untreated and previously treated chronic lymphocytic le…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers [Phase 2]
A Phase 2 clinical trial update on haploidentical stem cell transplantation for multiple hematologic cancers, with the study status reported…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Duvelisib and Nivolumab in Treating Patients With Richter Syndrome or Transformed Follicular Lymphoma [Phase 1]
A Phase 1 study evaluating the safety and preliminary efficacy of the combination of duvelisib and nivolumab in patients with Richter syndro…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma [Phase 1]
A Phase I safety, pharmacokinetic and pharmacodynamic study of KW-2478 in patients with multiple myeloma, chronic lymphocytic leukemia, or B…
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: Curcumin and Cholecalciferol in Treating Patients With Previously Untreated Stage 0-II Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial investigating curcumin and cholecalciferol in previously untreated stage 0-II chronic lymphocytic leukemia or small lymphocyti…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer [Phase 2]
Phase 2 study evaluating a conditioning regimen of fludarabine phosphate, cyclophosphamide, and total body irradiation followed by donor ste…
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: Umbilical & Cord Blood (CB) Derived CAR-Engineered NK Cells for B Lymphoid Malignancies [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating Umbilical Cord Blood-derived CAR-engineered NK cells for B lymphoid malignancies has completed with po…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: Nivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Richter Transformation [Phase 2]
Phase 2 trial evaluating nivolumab and ibrutinib in relapsed/refractory or high-risk untreated chronic lymphocytic leukemia, small lymphocyt…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant [Phase 1]
Phase 1 trial evaluating the CMV-MVA Triplex vaccine given to stem cell donors to prevent cytomegalovirus viremia in recipients of allogenei…
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CLINICAL_TRIALS trial_result · 2024-01-22Clinical Trial Update: Serologic Response to SHINGRIX Vaccine in Patients With CLL and WM Treated With BTK Inhibitors [EARLY_Phase 1]
Early-phase trial assessing serologic response to SHINGRIX in patients with CLL or WM treated with BTK inhibitors; completed with results po…
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Acalabrutinib and Venetoclax Treatment of Newly Diagnosed Patients With CLL at High Risk of Infection or Early Treatment [Phase 2, Phase 3]
A trial update on acalabrutinib and venetoclax for newly diagnosed CLL patients at high infection risk or early treatment phase (Phase 2/Pha…