Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies [Phase 1]
Phase 1 study of odronextamab in CD20+ B-cell malignancies completed; the trial reported safety and tolerability data in diseases including …
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic Leukemia [Phase 1]
Phase 1 trial evaluating cellular immunotherapy after chemotherapy in patients with recurrent B-cell lymphoid cancers, including Non-Hodgkin…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Double-blind, Randomized, Placebo-controlled, Prospective Phase III Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients With Chronic Lymphocytic Leukemia ("PRO-SID" Study) [Phase 3]
A Phase III study (PRO-SID) evaluating Panzyga for primary infection prophylaxis in patients with chronic lymphocytic leukemia and hypogamma…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Study Evaluating SC291 in Subjects With r/r B-cell Malignancies (ARDENT) [Phase 1]
Sana Biotechnology's investigational candidate SC291 is being studied in a Phase 1 ARDENT trial for relapsed/refractory B-cell malignancies,…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Addition of Loncastuximab Tesirine to Acalbrutinib , Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 trial update notes the addition of Loncastuximab tesirine to acalabrutinib for chronic lymphocytic leukemia; the study is active but…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Financial Difficulty in Patients With Blood Cancer
This clinical trial update notes the completion of a study evaluating financial difficulties experienced by patients with blood cancers, spe…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Ibrutinib in Combination With GA101 (Obinutuzumab) in Previously Untreated Chronic Lymphocytic Leukemia (CLL) Patients. [Phase 1, Phase 2]
This update reports results from a Phase 1/2 study evaluating the combination of ibrutinib with obinutuzumab (GA101) in previously untreated…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Augmented Virtual Reality for Reducing Pain, Stress, Anxiety and Improve Self Efficacy in Adult Cancer Patients Undergoing Chemotherapy in The West Bank [NA]
This completed clinical trial evaluated augmented virtual reality as a nonpharmacologic approach to reduce pain, stress, and anxiety and to …
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
This clinical trial update reports on safety, efficacy, and pharmacokinetics of mosunetuzumab as a single agent and with atezolizumab in chr…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemia [Phase 1]
Phase 1 trial of pitavastatin in combination with venetoclax for chronic lymphocytic leukemia or acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: BR101801 in Adult Patients With Advanced Hematologic Malignancies(Phase I) [Phase 1]
Phase I clinical trial update for BR101801 in adults with advanced hematologic malignancies; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL [Phase 2]
A Phase 2 pilot study evaluating metformin therapy in patients with relapsed or untreated chronic lymphocytic leukemia; the trial status is …
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Notch 1 Mutation in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patient
This ClinicalTrials.gov entry (NCT07157579) from Sohag University notes a study on Notch 1 mutation in chronic lymphocytic leukemia and non-…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Ibrutinib as Early Therapy in Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 study evaluating ibrutinib as early therapy for chronic lymphocytic leukemia and small lymphocytic leukemia; the trial is completed …
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Feasibility of a Whole-Food, Plant-Based Diet for Patients With Low-Risk Chronic Lymphocytic Leukemia (CLL) [NA]
This completed feasibility trial evaluated a whole-food, plant-based diet in patients with low-risk chronic lymphocytic leukemia (Stage A0),…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Calquence CLL rr Japan PMS_Japan Post-Marketing Surveillance (PMS) Study - All Patient Investigation
Post-marketing surveillance update for Calquence (acalabrutinib) in relapsed or refractory chronic lymphocytic leukemia, including small lym…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Cirmtuzumab Consolidation for Treatment of Patients With Detectable CLL on Venetoclax [Phase 2]
This update outlines a Phase 2 trial of Cirmtuzumab as consolidation therapy for patients with detectable chronic lymphocytic leukemia who a…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: 19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers [Phase 1]
This is a Phase 1 clinical trial update for a CAR T cell therapy (19(T2)28z1xx) in various B-cell cancers. The study is sponsored by Memoria…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial update assessing lenalidomide in combination with a vaccine therapy for patients with early-stage asymptomatic chroni…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Project to Improve Communication About Serious Illness - Pilot Study [NA]
Pilot study completed; results posted from a University of Washington project focused on improving communication about serious illness.
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of JNJ-64264681 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia [Phase 1]
This update reports the completion of a Phase 1 study evaluating JNJ-64264681 in participants with non-Hodgkin lymphoma and chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of JNJ-64264681 and JNJ-67856633 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia [Phase 1]
This is a completed Phase 1 clinical trial update for Janssen investigational agents JNJ-64264681 and JNJ-67856633 in participants with Non-…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of the MALT1 Inhibitor JNJ-67856633 and Ibrutinib in Combination in B-cell NHL and CLL [Phase 1]
A Phase 1 study evaluated the combination of the MALT1 inhibitor JNJ-67856633 with Ibrutinib in patients with chronic lymphocytic leukemia a…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL [Phase 2]
Phase 2 study evaluating the combination of acalabrutinib, venetoclax, and obinutuzumab as initial therapy for chronic lymphocytic leukemia;…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 clinical trial evaluating HLA-mismatched unrelated donor bone marrow transplantation with post-transplant cyclophosphamide; the stud…