Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: A Study of Motexafin Gadolinium for the Treatment of Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial of motexafin gadolinium for chronic lymphocytic leukemia was terminated.
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: Pentostatin, Alemtuzumab, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial evaluating a combination of pentostatin, alemtuzumab, and rituximab in relapsed or refractory chronic lymphocytic leukemia or …
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: Study of Low-Intensity Conditioning for Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 trial evaluating low-intensity conditioning for allogeneic stem cell transplantation in multiple myeloma, chronic lymphocytic leuk…
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: AZD6738 First Time in Patient Multiple Ascending Dose Study [Phase 1]
AZD6738 (berzosertib) was studied in a first-in-patient, multiple ascending-dose Phase 1 trial in relapsed/refractory hematologic cancers in…
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CLINICAL_TRIALS trial_result · 2014-05-26Clinical Trial Update: High-dose HMG-CoA Inhibitor Simvastatin Relapsed CLL [Phase 1]
This report covers a Phase 1 trial evaluating high-dose simvastatin, an HMG-CoA reductase inhibitor, in relapsed chronic lymphocytic leukemi…
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CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: Study of Noscapine for Patients With Low Grade Non Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia Refractory to Chemotherapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial of noscapine in patients with low-grade non-Hodgkin lymphoma or chronic lymphocytic leukemia refractory to chemot…
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CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: A Phase I/II Study of GX15-070MS in Untreated CLL [Phase 1]
A Phase I/II trial of GX15-070MS (obatoclax mesylate) in untreated chronic lymphocytic leukemia has completed the Phase 1 portion reported b…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Pentostatin, Cyclophosphamide, and Rituximab With or Without Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial assessing pentostatin, cyclophosphamide, and rituximab with or without bevacizumab in patients with chronic lymphocytic leukem…
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 trial evaluating obatoclax mesylate in combination with vincristine, doxorubicin, and dexrazoxane in pediatric patients with relapse…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: A Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GAGE) [Phase 2]
Phase 2 trial comparing two dosing regimens of obinutuzumab in previously untreated chronic lymphocytic leukemia; the study (GAGE) is comple…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Bryostatin 1 Plus Cladribine in Treating Patients With Relapsed Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 trial evaluated Bryostatin-1 in combination with Cladribine for relapsed chronic lymphocytic leukemia. The study has completed.
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Safety and Tolerability of XmAb®5574 in Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 study evaluating safety and tolerability of XmAb5574 in patients with chronic lymphocytic leukemia and small lymphocytic lymphoma …
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Sorafenib in Treating Patients With Relapsed Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial evaluating sorafenib for relapsed chronic lymphocytic leukemia was terminated; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-04-01Clinical Trial Update: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a) [Phase 3]
Phase 3 trial in previously untreated chronic lymphocytic leukemia evaluating obinutuzumab with chlorambucil completed.
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CLINICAL_TRIALS trial_result · 2014-03-31Clinical Trial Update: Safety of PCI-32765 in Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
Clinical trial update reporting safety data for the BTK inhibitor ibrutinib (PCI-32765) in patients with chronic lymphocytic leukemia and sm…
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CLINICAL_TRIALS trial_result · 2014-03-31Clinical Trial Update: T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating T-cell depleted allogeneic stem cell transplantation for hematologic malignancies; study is completed with…
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Ofatumumab + Chlorambucil vs Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial evaluating ofatumumab plus chlorambucil versus chlorambucil alone in previously untreated chronic lymphocytic leukemia; trial …
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Lenalidomide as Chemoprevention in Treating Patients With High-Risk, Early-Stage B-Cell Chronic Lymphocytic Leukemia [NA]
A terminated clinical trial evaluating lenalidomide as chemoprevention in high-risk, early-stage B-cell chronic lymphocytic leukemia has pos…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma [Phase 1]
Phase 1 study of oxaliplatin, ifosfamide, and etoposide in young patients with recurrent or refractory solid tumors or lymphomas; the trial …
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: The Duration of Humoral Immunity and the Memory Cell Function After Vaccination With 7-valent Pneumococcal Conjugate Vaccine in CLL [Phase 4]
Phase 4 study assessing how durable the humoral immune response and memory cell function are after vaccination with the 7-valent pneumococca…
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating CCI-779 (temsirolimus) in patients with recurrent or refractory B-cell non-Hodgkin lymphoma or chronic l…
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CLINICAL_TRIALS trial_result · 2014-02-10Clinical Trial Update: Sunitinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial evaluating sunitinib in relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma has completed with …
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: A Phase 1 Study of Novel GS-9973 Tablet Formulations to Evaluate the Effect of Acid Reducing Agents, Relative Bioavailability, and Food Effect on GS-9973 Pharmacokinetics [Phase 1]
Phase 1 study evaluating GS-9973 tablet formulations to assess the impact of acid-reducing agents, food, and relative bioavailability on pha…
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CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: A Trial of GS-9219 in Chronic Lymphocytic Leukemia (CLL), Non-Hodgkin's Lymphoma (NHL) or Multiple Myeloma (MM) [Phase 1, Phase 2]
Clinical trial GS-9219 in chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma (Phase 1/2) has been terminated.
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Treatment of B-Chronic Lymphocytic Leukemia (B-CLL) With Autologous CD40 Ligand and IL-2-Expressing Tumor Cells [Phase 1]
This completed Phase 1 study evaluated an autologous CD40 ligand approach combined with IL-2-expressing tumor cells for chronic lymphocytic …