Chronic Lymphocytic Leukemia
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CLINICAL_TRIALS trial_result · 2015-02-10Clinical Trial Update: A Study of Dinaciclib in Combination With Rituximab in Participants With Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (P07974) [Phase 1]
This Phase 1 trial evaluated the combination of dinaciclib and rituximab in patients with chronic lymphocytic leukemia and small lymphocytic…
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CLINICAL_TRIALS trial_result · 2015-02-03Clinical Trial Update: Ofatumumab Added to Dexamethasone in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial evaluated adding ofatumumab to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia, and the s…
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CLINICAL_TRIALS trial_result · 2015-01-27Clinical Trial Update: Rituximab, Cyclophosphamide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Low-Grade Follicular Lymphoma, Waldenstrom Macroglobulinemia, or Mantle Cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating rituximab, cyclophosphamide, bortezomib, and dexamethasone in relapsed/refractory low-grade follicular lym…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Stem Cell Transplantation for Patients With Cancers of the Blood [Phase 2]
Phase 2 trial update reporting results from stem cell transplantation for patients with blood cancers, including chronic myeloid leukemia, c…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update on methods to enhance safety and effectiveness of stem cell transplants.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: A Phase I Study of GNKG168 in Patient With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL) [Phase 1]
This clinical trial update reports that GNKG168 in relapsed or refractory B-cell chronic lymphocytic leukemia (Phase I) has been terminated.
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CLINICAL_TRIALS trial_result · 2014-11-24Clinical Trial Update: Ofatumumab vs Physician's Choice in Subjects With Bulky Fludarabine-Refractory Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial comparing Ofatumumab to physician's choice in bulky, fludarabine-refractory chronic lymphocytic leukemia has completed with re…
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CLINICAL_TRIALS trial_result · 2014-11-10Clinical Trial Update: A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives [Phase 2]
Phase 2 clinical trial investigating a two-step bone marrow transplant using cells from two partially matched relatives was terminated; resu…
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: Maintenance Therapy: Lenalidomide Following Bendamustine and Rituximab Induction Therapy for Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial tested lenalidomide as maintenance therapy after Bendamustine and Rituximab induction in chronic lymphocytic leukemia; the s…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Bendamustine Hydrochloride (HCl) in Indolent Non-Hodgkin's Lymphoma That Has Progressed During or Following Treatment With a Rituximab Regimen or Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
A Phase 3 trial of bendamustine hydrochloride for indolent non-Hodgkin lymphoma and chronic lymphocytic leukemia completed, with results pos…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: A Randomized, Double-Blind, Placebo-Controlled Study of Idelalisib in Combination With Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL) [Phase 3]
A Phase 3 randomized, double-blind trial evaluating idelalisib plus rituximab vs control in previously treated chronic lymphocytic leukemia …
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CLINICAL_TRIALS trial_result · 2014-10-10Clinical Trial Update: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 2) [Phase 3]
Phase 3 trial of obinutuzumab with chlorambucil in previously untreated chronic lymphocytic leukemia completed, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports a terminated phase 1/2 trial evaluating fenretinide with rituximab for B-cell non-Hodgkin lymphomas; …
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CLINICAL_TRIALS trial_result · 2014-09-11Clinical Trial Update: Investigation of the Cylex® ImmuKnow® Assay
A completed clinical trial investigating the Cylex ImmuKnow immune function assay across several hematologic diseases.
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CLINICAL_TRIALS trial_result · 2014-09-10Clinical Trial Update: CHAIROS Study A Study of MabThera/Rituxan (Rituximab) Maintenance Therapy in Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Naive to Chemotherapy [Phase 2]
Phase 2 trial update describing results for Rituximab maintenance therapy in patients with chronic lymphocytic leukemia naive to chemotherap…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: Phase 2 Fludarabine, Cytoxan and FCCAM <Alemtuzumab> in Untreated B-Cell Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial of fludarabine, cyclophosphamide and alemtuzumab in untreated B-cell chronic lymphocytic leukemia has completed with results p…
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CLINICAL_TRIALS trial_result · 2014-09-03Clinical Trial Update: Clinical Study of Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) [Phase 1]
A Phase 1 clinical study in relapsed/refractory chronic lymphocytic leukemia sponsored by Piramal Enterprises is currently suspended.
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Lenalidomide in Comb w/Rituximab for Pts w/CD5+/CD20+ Hem Malignancies Who Relapse/Progress After Rituximab [Phase 2]
A phase 2 trial evaluating lenalidomide plus rituximab in patients with CD5+/CD20+ hematologic malignancies who relapse after rituximab, inc…
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CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: Lenalidomide Following Fludarabine/Rituximab (FR) in Untreated Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating lenalidomide after fludarabine/rituximab in untreated chronic lymphocytic leukemia has completed with results poste…
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CLINICAL_TRIALS trial_result · 2014-08-13Clinical Trial Update: A Phase I Trial Using Cyclophosphamide, Rituximab and Revlimid (CR2) for the Treatment of Relapsed/Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL) and Small Lymphocytic Lymphoma (SLL) [Phase 1]
This document reports the termination of a Phase I trial evaluating cyclophosphamide, rituximab, and lenalidomide (CR2) for relapsed/refract…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: Rituximab and GM-CSF in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating rituximab in combination with GM-CSF for chronic lymphocytic leukemia; the study is terminated.
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CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Safety and Tolerability Study of PCI-32765 Combined With Fludarabine/Cyclophosphamide/Rituximab (FCR) and Bendamustine/Rituximab (BR) in Chronic Lymphocytic Leukemia (CLL) [Phase 1]
Phase 1 safety and tolerability study evaluating the BTK inhibitor PCI-32765 (ibrutinib) in combination with FCR or BR regimens in chronic l…
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Phase IV Observational Study in Chronic Lymphocytic Leukemia
GlaxoSmithKline conducted a Phase IV observational study in chronic lymphocytic leukemia. The study status is COMPLETED.
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Open-label Extension Study of Navitoclax in Subjects With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
This document provides an update on an open-label extension phase 2 trial of navitoclax in patients with chronic lymphocytic leukemia, notin…
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: A Proof of Concept Study of the Safety, Tolerability, and Efficacy of Avastin (Bevacizumab) in Patients With Chemo-naive Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 proof-of-concept trial evaluating Avastin (bevacizumab) for safety, tolerability, and efficacy in chemo-naive chronic lymphocytic le…