Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-10-19Clinical Trial Update: Safety, Pharmacodynamics, Pharmacokinetics, and Efficacy of GS-9901 in Adults With Relapsed or Refractory Follicular Lymphoma, Marginal Zone Lymphoma, Chronic Lymphocytic Leukemia, or Small Lymphocytic Lymphoma [Phase 1]
Phase 1 study of GS-9901 in adults with relapsed or refractory follicular lymphoma, marginal zone lymphoma, chronic lymphocytic leukemia, or…
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CLINICAL_TRIALS trial_result · 2015-10-15Clinical Trial Update: Campath Maintenance in Chronic Lymphocytic Leukemia [NA]
This update reports that Campath (alemtuzumab) maintenance for chronic lymphocytic leukemia was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: A Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial updating results for ibrutinib versus ofatumumab in relapsed/refractory CLL and SLL; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Sorafenib for the Treatment of Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial of sorafenib for chronic lymphocytic leukemia was terminated; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: Lumiliximab With Fludarabine, Cyclophosphamide, and Rituximab (FCR) Versus FCR Alone in Subjects With Relapsed Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial comparing lumiliximab added to FCR versus FCR alone in relapsed chronic lymphocytic leukemia; the study was terminated.
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: Lumiliximab in Combination With FCR in Subjects With Relapsed Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
Completion of a Phase 1/2 trial evaluating lumiliximab in combination with the FCR regimen for relapsed chronic lymphocytic leukemia.
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: Evaluation of Safety and Efficacy of Fludarabine, Cyclophosphamide, and Rituximab (FCR) +/- Lumiliximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating the safety and efficacy of fludarabine, cyclophosphamide, and rituximab, with or without lumiliximab, in previously…
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CLINICAL_TRIALS trial_result · 2015-09-29Clinical Trial Update: Phase II Study of High-Dose Rituximab in High-Risk Chronic Lymphocytic Leukemia Patients in Suboptimal Response After Induction Immunochemotherapy [Phase 2]
Phase II study of high-dose rituximab in high-risk chronic lymphocytic leukemia patients who had suboptimal response to induction immunochem…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit [Phase 2]
Phase 2 clinical trial evaluating hematopoietic stem cell transplantation using a CD34-selected mismatched related donor plus one umbilical …
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CLINICAL_TRIALS trial_result · 2015-09-23Clinical Trial Update: A Phase I/II Study to Assess the Safety and Tolerability of APO866 for the Treatment of Refractory B-CLL [Phase 1, Phase 2]
A Phase I/II trial evaluating the safety and tolerability of APO866 in patients with refractory B-cell chronic lymphocytic leukemia has comp…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Pilot Study of Radiation-Enhanced Allogeneic Cell Therapy for Progressive Hematologic Malignancy After Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 pilot trial evaluating radiation-enhanced allogeneic cell therapy for progressive hematologic malignancies after allogeneic stem cel…
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CLINICAL_TRIALS trial_result · 2015-08-27Clinical Trial Update: Lenalidomide and Rituximab as Treatment of Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating lenalidomide in combination with rituximab for chronic lymphocytic leukemia and small lymphocytic lymphoma…
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: FCR Plus Sargramostim (GM-CSF) as Frontline Therapy for Symptomatic Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating FCR chemotherapy plus sargramostim (GM-CSF) as frontline therapy for symptomatic chronic lymphocytic leukemia; resu…
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1]
Phase 1 study evaluating the combination of methoxyamine and fludarabine phosphate in adults with relapsed or refractory hematologic maligna…
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: A Phase I/II, Open-label Study of Ofatumumab Added to Chlorambucil in Previously Untreated Japanese Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase I/II open-label trial evaluating adding ofatumumab to chlorambucil in previously untreated Japanese patients with chronic lymphocytic …
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: SCH 727965 in Patients With Mantle Cell Lymphoma or B-Cell Chronic Lymphocytic Leukemia (Study P04715) [Phase 2]
A Phase 2 study of SCH 727965 in mantle cell lymphoma or B-cell chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Combination Chemotherapy in Treating Patients With Chronic Lymphocytic Leukemia or Lymphocytic Lymphoma [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 evaluation of a combination chemotherapy regimen in patients with chronic lymphocytic leuke…
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: Antiviral Treatment of Chronic Lymphocytic Leukemia [Phase 4]
A Phase 4 clinical trial update reports completion of an antiviral treatment study for Chronic Lymphocytic Leukemia conducted by the Medical…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery [Phase 1]
Phase 1 study sponsored by the National Cancer Institute evaluating dasatinib in patients with metastatic or unresectable solid tumors and l…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: A Phase II Study of MGCD0103 (MG-0103) in Patients With Refractory Chronic Lymphocytic Leukemia [Phase 2]
This update reports on a completed Phase II trial of MGCD0103 (mocetinostat) in patients with refractory Chronic Lymphocytic Leukemia.
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CLINICAL_TRIALS trial_result · 2015-06-30Clinical Trial Update: 5-Azacytidine (Azacytidine; Vidaza) in Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial of azacitidine (Vidaza) in chronic lymphocytic leukemia was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-25Clinical Trial Update: A Study of MabThera Added to Bendamustine or Chlorambucil in Patients With Chronic Lymphocytic Leukemia (MaBLe) [Phase 4]
Phase 4 trial evaluating adding rituximab (MabThera) to bendamustine or chlorambucil in chronic lymphocytic leukemia has completed. Results …
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: A Phase II, Open Label, Single Arm, Multicenter Study of Chlorambucil in Japanese Previously Untreated Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase II, open-label, single-arm multicenter trial of chlorambucil in Japanese patients with previously untreated chronic lymphocytic leukem…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and biological activity of oral clioquinol in patients with relapsed or refracto…