Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-09-12Clinical Trial Update: Single Treatment With FT1050 of an Ex-vivo Modulated Umbilical Cord Blood Unit [Phase 1]
This update reports the completion of a Phase 1 trial evaluating a single treatment with FT1050, an ex-vivo modulated umbilical cord blood u…
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: Fludarabine, Cyclophosphamide, and Rituximab - High Dose Frontline [Phase 2]
Phase 2 trial evaluating high-dose frontline fludarabine, cyclophosphamide, and rituximab in chronic lymphocytic leukemia; results posted af…
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies [Phase 1]
This Phase 1 clinical trial update reports on an anti-CD19 CAR-T cell therapy being tested in patients with B cell malignancies, including c…
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update for PCAR-019 evaluating efficacy and safety in CD19-positive relapsed or refractory leukemia and lymphoma across Phase…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Efficacy/Safety of Frontline Alemtuzumab (Campath, MabCampath) vs Chlorambucil in Patients With Progressive B-Cell Lymphocytic Leukemia [Phase 3]
A Phase 3 trial comparing frontline alemtuzumab (Campath, MabCampath) to chlorambucil in progressive B-cell chronic lymphocytic leukemia has…
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CLINICAL_TRIALS trial_result · 2016-07-26Clinical Trial Update: Hydroxychloroquine in Untreated B-CLL Patients [Phase 2]
A Phase 2 trial evaluating hydroxychloroquine in untreated B-cell chronic lymphocytic leukemia was terminated, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-07-25Clinical Trial Update: Ofatumumab Added to Fludarabine-Cyclophosphamide vs Fludarabine-Cyclophosphamide Combination in Relapsed Subjects With Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial evaluating ofatumumab added to fludarabine-cyclophosphamide versus fludarabine-cyclophosphamide in relapsed chronic lymphocyti…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Fludarabine and Monoclonal Antibody Therapy in Treating Patients With Untreated B-cell Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating the combination of fludarabine with a monoclonal antibody for untreated B-cell chronic lymphocytic leukemia has com…
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders [Phase 2]
A Phase 2 trial testing nonmyeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors for multiple hematologic dis…
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: Safety, Tolerability and Efficacy of A6 in Patients With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
A Phase 2 trial evaluating the investigational drug A6 for chronic lymphocytic leukemia and small lymphocytic lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Study of IPI-145 in Combination With Rituximab or Bendamustine/Rituximab in Hematologic Malignancies [Phase 1]
Phase 1 study of idelalisib (IPI-145) in combination with Rituximab or Bendamustine/Rituximab in hematologic malignancies has completed.
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Fludarabine Followed by Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
This Phase 2 trial evaluates sequencing fludarabine followed by alemtuzumab in patients with chronic lymphocytic leukemia, and the study has…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Ribomustin in the First Line Therapy of Chronic Lymphocytic Leukemia
This document reports on a completed clinical trial evaluating Ribomustin (bendamustine) as first-line therapy for chronic lymphocytic leuke…
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CLINICAL_TRIALS trial_result · 2016-06-28Clinical Trial Update: Akt Inhibitor MK2206, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial of Akt inhibitor MK2206 combined with bendamustine and rituximab in relapsed CLL or small lymphocytic lymphoma has completed…
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CLINICAL_TRIALS trial_result · 2016-06-24Clinical Trial Update: A Study of Obinutuzumab (GA101; RO5072759) in Combination With Chemotherapy in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GALTON) [Phase 1]
This clinical trial update reports Phase 1 results for obinutuzumab in combination with chemotherapy in previously untreated chronic lymphoc…
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Pilot Study of Autologous T Lymphocytes With ADCC in Patients With CD20-Positive B-Cell Malignancies [Phase 1, Phase 2]
Phase 1/Phase 2 pilot study evaluating autologous T lymphocytes with antibody-dependent cellular cytotoxicity in CD20-positive B-cell malign…
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CLINICAL_TRIALS trial_result · 2016-06-21Clinical Trial Update: Multicentre Registry of Treatments and Outcomes in Patients With Chronic Lymphocytic Leukaemia (CLL) Or Indolent Non Hodgkin's Lymphoma (iNHL)
A multicenter registry examining treatments and outcomes for patients with chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma ha…
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)
A Stanford-sponsored clinical trial evaluating allogeneic transplantation for acute and chronic leukemias has been terminated.
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Dose Escalation Study of Revlimid With Fludarabine-Rituximab for CLL/SLL [Phase 1]
A Phase 1 dose-escalation study of lenalidomide (Revlimid) with fludarabine-rituximab in patients with chronic lymphocytic leukemia and smal…
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CLINICAL_TRIALS trial_result · 2016-05-26Clinical Trial Update: Fludarabine/Rituximab Combined With Escalating Doses of Lenalidomide in Untreated CLL [Phase 1, Phase 2]
This update reports results from a Phase 1/2 trial evaluating escalating doses of lenalidomide added to fludarabine and rituximab in previou…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Weekly Subcutaneous Alemtuzumab and Rituximab for Relapsed CLL [Phase 1]
Phase 1 trial evaluating weekly subcutaneous alemtuzumab and rituximab for relapsed chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL) [Phase 2]
A Phase 2 study of lenalidomide in previously untreated, symptomatic chronic lymphocytic leukemia was terminated. Results were posted in 201…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer [Phase 1, Phase 2]
Phase 1/2 study evaluating a four-drug regimen (pentostatin, cyclophosphamide, rituximab, mitoxantrone) in patients with chronic lymphocytic…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL) [Phase 1]
Phase 1 study of carfilzomib in patients with chronic lymphocytic leukemia, small lymphocytic lymphoma, or prolymphocytic leukemia has compl…
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: Open-label Phase 3 BTK Inhibitor Ibrutinib vs Chlorambucil Patients 65 Years or Older With Treatment-naive CLL or SLL [Phase 3]
Phase 3 open-label trial comparing ibrutinib to chlorambucil in patients 65 years or older with treatment-naive chronic lymphocytic leukemia…