Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating TRU-016 plus bendamustine versus bendamustine alone in relapsed chronic lymphocytic leukemia has completed with r…
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: Trial of Pentostatin Plus Cyclophosphamide With Ofatumumab (PCO) in Older Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating pentostatin, cyclophosphamide, and ofatumumab (PCO) in older patients with chronic lymphocytic leukemia has complet…
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: Biomarker To Evaluate Protein Profiles of Neutropenic Fever/Infection With Acute or Chronic Leukemias
This completed clinical trial investigates protein biomarker profiles in neutropenic fever/infection among patients with acute or chronic le…
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CLINICAL_TRIALS trial_result · 2016-12-22Clinical Trial Update: A Phase II Study of Doxycycline in Relapsed NHL [Phase 2]
Phase II trial of doxycycline in relapsed non-Hodgkin lymphoma was terminated and results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: Revlimid® as Consolidation Treatment Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 study of lenalidomide (Revlimid) as consolidation therapy in chronic lymphocytic leukemia was terminated; results were posted in 201…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating everolimus with alemtuzumab in recurrent chronic lymphocytic leukemia or small lymphocytic lymphoma has completed…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Chemotherapy in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating chemotherapy in patients with previously untreated chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Gemcitabine in Treating Patients With Recurrent Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial evaluating gemcitabine in patients with recurrent chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: PCAR-119 Bridge Immunotherapy Prior to Stem Cell Transplant in Treating Patients With CD19 Positive Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update describing the evaluation of PCAR-119 Bridge Immunotherapy as a pre-transplant treatment for CD19-positive leukemias a…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Pilot Study to Establish Safety & Efficacy of a Combination of Dexamethasone and Lenalidomide in Patients With Relapsed or Refractory Chronic Lymphocytic Leukaemia (CLL) [Phase 2]
A Phase 2 pilot study assessed the safety and efficacy of combining dexamethasone with lenalidomide in patients with relapsed or refractory …
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia [Phase 2]
This document reports results from a Phase 2 expanded-access, open-label study of obinutuzumab plus chlorambucil in previously untreated chr…
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CLINICAL_TRIALS trial_result · 2016-11-03Clinical Trial Update: Fludarabine, Cyclophosphamide, and Rituximab Versus Pentostatin, Cyclophosphamide, and Rituximab in Previously Untreated or Treated B-Cell Chronic Lymphocytic Leukemia Patients [Phase 3]
A Phase 3 trial comparing fludarabine, cyclophosphamide, and rituximab (FCR) versus pentostatin, cyclophosphamide, and rituximab (PCR) in ad…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of ABT-263 in Combination With Dose-Intensive Rituximab, or Dose-Intensive Rituximab Alone, in Previously Untreated Patients With B-Cell, Chronic Lymphocytic Leukemia (CLL) [Phase 2]
This completed Phase 2 study evaluated navitoclax (ABT-263) in combination with dose-intensive rituximab versus rituximab alone in previousl…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of the Safety and Pharmacokinetics of Escalating Doses of DCDT2980S in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia And DCDT2980S in Combination With Rituximab in Patients With Relapsed or Refractory B-Cell Non Hodgkin's Lymphoma [Phase 1]
This Phase 1 trial evaluated escalating doses of DCDT2980S, both alone and in combination with rituximab, in adults with relapsed or refract…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: An Observational Study on the Safety Profile of MabThera/Rituxan (Rituximab) in Combination With Chemotherapy in Patients With B Cell-lineage Chronic Lymphocytic Leukaemia (MABERYC)
An observational study assessing the safety profile of Rituximab in combination with chemotherapy for patients with chronic lymphocytic leuk…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: Rituximab in Combination With Fludarabine and Cyclophosphamide in Patients With Chronic Lymphocytic Leukemia
This entry reports a completed clinical trial evaluating rituximab in combination with fludarabine and cyclophosphamide for chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update on CD19-targeted CAR-T cell therapy being tested in relapsed/refractory leukemias and lymphomas (Phase 1 and Phase 2).
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Flavopiridol in Treating Patients With Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia [Phase 2]
This Phase 2 clinical trial evaluated flavopiridol in patients with chronic lymphocytic leukemia and prolymphocytic leukemia; the study was …
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: 8-Chloro-Adenosine in Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 results for a trial of 8-Chloro-Adenosine in chronic lymphocytic leukemia have completed. The snippet does not include efficacy resu…
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CLINICAL_TRIALS trial_result · 2016-10-03Clinical Trial Update: Fludarabine, Cyclophosphamide, and Alemtuzumab in Patients With B-cell Chronic Lymphatic Leukemia (B-CLL) [Phase 2]
A Phase 2 clinical trial evaluating the combination of fludarabine, cyclophosphamide, and alemtuzumab in patients with chronic lymphocytic l…
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CLINICAL_TRIALS trial_result · 2016-10-03Clinical Trial Update: Combination Chemotherapy and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia (CLL) That Did Not Respond to Fludarabine, CLL With Autoimmune Haemolytic Anemia (AIHA) or Richter's Transformation (RT) [Phase 2]
Phase 2 trial evaluating rituximab-based combination chemotherapy in patients with chronic lymphocytic leukemia that did not respond to flud…
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: Ruxolitinib in the Treatment of Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
This update reports the completion of Phase 1 and Phase 2 trials evaluating ruxolitinib for chronic lymphocytic leukemia.
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: Combination Chemotherapy, Total-Body Irradiation, and Alemtuzumab in Treating Patients Undergoing an Autologous Stem Cell Transplant for Stage I, Stage II, Stage III, or Stage IV Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating a regimen of combination chemotherapy, total-body irradiation, and alemtuzumab in patients undergoing auto…
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: Combination Chemotherapy With or Without G-CSF in Treating Patients With Relapsed Chronic Lymphocytic Leukemia [Phase 3]
A Phase 3 trial comparing combination chemotherapy with versus without G-CSF in relapsed chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: Ofatumumab Induction and Maintenance in Elderly Patients With Poor Risk CLL in the Context of Allogeneic Transplantation [Phase 2]
Phase 2 trial evaluating induction and maintenance with ofatumumab in elderly patients with poor-risk chronic lymphocytic leukemia undergoin…