Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders [NA]
This update reports the completed status of a trial assessing bone marrow and kidney transplant for patients with chronic kidney disease and…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma [Phase 2]
Phase 2 trial evaluating ixazomib citrate with rituximab in indolent B-cell non-Hodgkin lymphoma has posted results.
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: A Vaccine Booster (GEO-CM04S1) for the Prevention of COVID-19 in Patients With Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating a vaccine booster GEO-CM04S1 to prevent COVID-19 in patients with chronic lymphocytic leukemia, currentl…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2) [Phase 1, Phase 2]
Clinical Trial Update on the ALPHA2 Phase 1/2 study evaluating ALLO-501A anti-CD19 allogeneic CAR T cells in adults with relapsed/refractory…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Bendamustine/Rituximab Followed by Venetoclax and Rituximab for Treatment of Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 study evaluating Bendamustine/Rituximab followed by Venetoclax and Rituximab for chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Study of BGB-10188 as Monotherapy, and in Combination With Zanubrutinib, and Tislelizumab [Phase 1, Phase 2]
BeiGene announced completion and posted results for a Phase 1/2 study of BGB-10188 as monotherapy and in combination with zanubrutinib and t…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Calquence CLL 1L Japan PMS _ Japan Post-Marketing Surveillance (PMS) Study
Post-marketing surveillance study in Japan evaluating Calquence (acalabrutinib) as first-line therapy for previously untreated chronic lymph…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Venetoclax and Ibrutinib in Treating Patients With Chronic or Small Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial update evaluating venetoclax in combination with ibrutinib for chronic lymphocytic leukemia and small lymphocytic lym…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Atezolizumab, Obinutuzumab, and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Relapsed or Refractory Richter Syndrome [Phase 2]
Phase 2 clinical trial evaluating a triple-drug regimen (atezolizumab, obinutuzumab, and venetoclax) for chronic lymphocytic leukemia, small…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of PRGN-3007 UltraCAR-T cells in patients with advanced hematologic and solid tumors has complet…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Venetoclax and Ibrutinib in Treating in Participants With Chronic Lymphocytic Leukemia and Ibrutinib Resistance Mutations [Phase 2]
This is a Phase 2 clinical trial update assessing the combination of venetoclax and ibrutinib in participants with chronic lymphocytic leuke…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia [Phase 3]
A Phase 3 trial is evaluating whether adding venetoclax to the standard combination of ibrutinib and obinutuzumab improves outcomes in untre…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: T-cells or EBV Specific CTLs, Advanced B-Cell NHL and CLL [Phase 1]
Phase 1 trial evaluating EBV-specific cytotoxic T lymphocytes for advanced B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia has …
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: A Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
Phase 1/2 study evaluating the safety, pharmacokinetics, and efficacy of the combination of tafasitamab and parsaclisib in relapsed/refracto…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Bcl-2 Inhibitor GDC-0199 in Combination With Obinutuzumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or Previously Untreated Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial results update for GDC-0199 (venetoclax) in combination with obinutuzumab and ibrutinib in relapsed/refractory or previously…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial of the oral BTK inhibitor LOXO-305 (pirtobrutinib) in patients with previously treated chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies [Phase 1]
A Phase 1 clinical trial evaluates PRT2527 as a standalone therapy and in combination with zanubrutinib or venetoclax for relapsed/refractor…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab [Phase 2]
Phase 2 study evaluating disease risk mutation-guided finite acalabrutinib plus venetoclax for relapsed chronic lymphocytic leukemia and sma…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL [Phase 3]
A Phase 3 global trial (ROCKET-CLL) comparing rocbrutinib to pirtobrutinib in patients previously treated with covalent BTK inhibitors and w…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies [Phase 1]
A Phase 1 clinical trial update for a bicistronic CAR-T cell therapy targeting CD19 and CD20 in B-cell malignancies; current status is not r…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) [Phase 1]
Phase 1 trial update of ABBV-453 in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma, focusing on adverse eve…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: ACY-1215 in Combination With BCR Pathway Inhibitors in Relapsed CLL [Phase 1]
Phase 1 clinical trial update evaluating ACY-1215 (ricolinostat) in combination with B-cell receptor pathway inhibitors for relapsed chronic…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating an anti-pneumococcal vaccine strategy in patients with Chronic Lymphocytic Leukemia and Small lymphocyti…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Ibrutinib lead-in Followed by Venetoclax Plus Ibrutinib in Patients With RR CLL [Phase 2]
A Phase 2 trial evaluating an ibrutinib lead-in followed by venetoclax plus ibrutinib in relapsed/refractory chronic lymphocytic leukemia. T…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL [Phase 1]
Clinical trial update for a Phase 1 study evaluating autologous peripheral blood lymphocytes in chronic lymphocytic leukemia and small lymph…