Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-12-21Clinical Trial Update: A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating obinutuzumab plus bendamustine in previously untreated chronic lymphocytic leukemia has completed with results post…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating fludarabine phosphate with total-body irradiation as conditioning before donor peripheral blood stem cell transplan…
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: A Pilot Trial With Subcutaneous Alemtuzumab and Oral Fludarabinephosphate for the Determination of Safety, Efficacy and Molecular Profiling for the Prediction of Response [Phase 2]
Phase 2 trial evaluating subcutaneous alemtuzumab with oral fludarabine phosphate for safety, efficacy, and molecular profiling to predict r…
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating autologous stem cell transplant followed by donor stem cell transplant in relapsed or refractory lymphom…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Yttrium Y 90 Anti-CD19 Antibody BU-12 in Patients With Advanced Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 trial of BU-12, a Yttrium-90 labeled anti-CD19 antibody, in advanced relapsed or refractory acute lymphoblastic leukemia or chronic …
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Study to Assess the Effect of Rifampin on the Metabolism of Navitoclax [Phase 1]
Phase 1 trial update evaluating the effect of rifampin on navitoclax metabolism; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Ofatumumab in Japanese Patients With CD20 Positive Follicular Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
This is a Phase 1 clinical trial update for the anti-CD20 antibody ofatumumab in Japanese patients with CD20-positive follicular lymphoma or…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Lenalidomide in Acute Leukemias and Chronic Lymphocytic Leukemia. [Phase 1]
This update reports the completion of a Phase 1 trial evaluating lenalidomide in acute myeloid leukemia, acute lymphoblastic leukemia, and c…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Vorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, or Relapsed B Cell Non-Hodgkin's Lymphoma [Phase 2]
This Phase 2 trial evaluated the combination of vorinostat, cladribine, and rituximab in patients with mantle cell lymphoma, relapsed chroni…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Ofatumumab Cardiac Repolarization (QTc) Study in Fludarabine-Refractory Chronic Lymphocytic Leukemia Subjects [Phase 1]
A Phase 1 study evaluating the effect of ofatumumab on cardiac repolarization (QTc) in patients with fludarabine-refractory chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Chemotherapy, Total-Body Irradiation, Rituximab, and Donor Stem Cell Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
This Phase 2 study evaluated a conditioning regimen combining chemotherapy, total-body irradiation, and rituximab followed by donor stem cel…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: Tositumomab and Iodine I 131 Tositumomab in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma in First Remission [Phase 2]
This clinical trial update reports Phase 2 results for tositumomab in combination with iodine-131 for treating chronic lymphocytic leukemia …
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CLINICAL_TRIALS trial_result · 2017-10-11Clinical Trial Update: Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab in Adults With Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
A Phase 3 trial evaluating idelalisib in combination with bendamustine and rituximab for previously untreated chronic lymphocytic leukemia h…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: CD19-specific T-cell for Chronic Lymphocytic Leukemia (CLL) [Phase 1]
Phase 1 trial evaluating CD19-specific T-cell therapy for Chronic Lymphocytic Leukemia has completed.
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplant [Phase 2]
Phase 2 clinical trial update assessing safety and tolerability of HSC835 in patients with hematological malignancies undergoing single umbi…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Rituximab Maintenance Versus Observation After First-line Immunochemotherapy by FCR in Older Patients With Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial evaluating Rituximab maintenance versus observation after first-line immunochemotherapy (FCR) in older patients with chronic l…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms
Completed clinical trial evaluating whether the final Geriatric Assessment in Haematology (GAH) score can predict tolerance to treatment in …
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia [Phase 1, Phase 2]
This clinical trial update reports Phase 1/Phase 2 results for fludarabine and cyclophosphamide as conditioning therapy for donor stem cell …
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Study of Bendamustine/Rituxan Induction Chemotherapy With Revlimid Maintenance for Relapsed/Refractory CLL and SLL [Phase 2]
Phase 2 trial evaluating bendamustine/rituxan induction chemotherapy followed by Revlimid maintenance in relapsed/refractory chronic lymphoc…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Lenalidomide With or Without Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating lenalidomide with or without rituximab in relapsed or refractory chronic lymphocytic leukemia has completed and res…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: A Trial of the Safety of Escalating Doses of PRO131921 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
A Phase 1/2 trial evaluating escalating doses of PRO131921 in relapsed or refractory chronic lymphocytic leukemia was terminated.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Lower But More Frequent Dose Rituximab to Treat Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 trial evaluated a lower, more frequent dosing regimen of rituximab for refractory chronic lymphocytic leukemia, with the study sta…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Efficacy and Safety of Idelalisib in Combination With Obinutuzumab Compared to Chlorambucil in Combination With Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial comparing idelalisib plus obinutuzumab versus chlorambucil plus obinutuzumab in previously untreated chronic lymphocytic leuke…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Phase 1/1b Study of TRU-016 in Patients With Previously Treated CLL or Select Subtypes of Non-Hodgkin's Lymphoma [Phase 1]
The Phase 1/1b study of TRU-016 in patients with previously treated Chronic Lymphocytic Leukemia or select subtypes of Non-Hodgkin's Lymphom…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy [Phase 1]
Phase 1 interaction study assessing the effect of CYP3A inhibitors on ibrutinib exposure in patients with chronic lymphocytic leukemia; the …