Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-12-30Clinical Trial Update: Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial evaluating three regimens for older patients with previously untreated chronic lymphocytic leukemia: Rituximab plus Bendamusti…
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CLINICAL_TRIALS trial_result · 2019-12-23Clinical Trial Update: Immunotherapy With CD22 CAR T-cells for B-Cell Lymphoma, ALL and CLL [Phase 1, Phase 2]
Clinical trial update on CD22 CAR T-cells for B-cell lymphoma, acute lymphoblastic leukemia, and chronic lymphocytic leukemia across Phase 1…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults [Phase 2]
Phase 2 trial investigating an immunosuppressive regimen followed by blood cell transplant for treating blood cancers in older adults; compl…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Combination Study of IPH2201 (Monalizumab) With Ibrutinib in Relapsed, Refractory or Previously Untreated CLL [Phase 1, Phase 2]
A two-phase early-stage trial evaluated IPH2201 (monalizumab) in combination with ibrutinib for chronic lymphocytic leukemia; the study is t…
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: Rituximab in Pretreated Elderly or Unfit B-CLL Patients [Phase 2]
Phase 2 clinical trial evaluating rituximab in pretreated elderly or unfit patients with B-cell chronic lymphocytic leukemia has completed w…
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CLINICAL_TRIALS trial_result · 2019-12-09Clinical Trial Update: Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant [Phase 2]
Phase 2 trial investigating sirolimus, cyclosporine, and mycophenolate mofetil to prevent graft-versus-host disease in patients with blood c…
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: A Study Evaluating the Efficacy of Obinutuzumab and Bendamustine Treatment in Participants With Refractory or Relapsed Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating obinutuzumab with bendamustine in relapsed/refractory chronic lymphocytic leukemia has completed with results poste…
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CLINICAL_TRIALS trial_result · 2019-11-22Clinical Trial Update: Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies [Phase 2]
Phase 2 clinical trial assessing donor atorvastatin to prevent severe acute GVHD after nonmyeloablative peripheral blood stem cell transplan…
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating ex vivo-activated autologous lymph node lymphocytes in patients with chronic lymphocytic leukemia; study s…
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CLINICAL_TRIALS trial_result · 2019-10-24Clinical Trial Update: Subcutaneous Alemtuzumab Combined With Oral Dexamethasone, Followed by Alemtuzumab Maintenance or Allo-SCT in CLL With 17p- or Refractory to Fludarabine [Phase 2]
Phase 2 clinical trial evaluating subcutaneous alemtuzumab with oral dexamethasone followed by alemtuzumab maintenance or allo-SCT in CLL wi…
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CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia [Phase 2]
Phase 2 clinical trial assessing management of platelet transfusion therapy in patients with blood cancers or treatment-induced thrombocytop…
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CLINICAL_TRIALS trial_result · 2019-10-17Clinical Trial Update: Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating peripheral stem cell transplantation with combination chemotherapy in low-grade non-Hodgkin's lymphoma or chronic l…
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Comparison of the Treatments of Obinutuzumab + Venetoclax Versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 clinical trial comparing obinutuzumab plus venetoclax versus obinutuzumab plus chlorambucil in chronic lymphocytic leukemia; the stu…
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CLINICAL_TRIALS trial_result · 2019-09-25Clinical Trial Update: Fludarabine, Bendamustine, and Rituximab (FBR) for Relapsed Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating fludarabine, bendamustine, and rituximab (FBR) for relapsed chronic lymphocytic leukemia has completed w…
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CLINICAL_TRIALS trial_result · 2019-09-24Clinical Trial Update: An Open-Label Phase 2 Study of Ofatumumab (Arzerra) in Combination With Oral GSK2110183 in the Treatment of Relapsed and Refractory Chronic Lymphocytic Leukemia (CLL) [Phase 2]
An open-label Phase 2 study evaluating the combination of Ofatumumab (Arzerra) with GSK2110183 in relapsed/refractory chronic lymphocytic le…
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: Dimethylfumarate (DMF) in Relapsed/Refractory CLL/SLL [Phase 1]
Phase 1 trial evaluating dimethylfumarate in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma; study terminat…
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CLINICAL_TRIALS trial_result · 2019-09-18Clinical Trial Update: Phase 2 Study of the Combination of Bruton's Tyrosine Kinase Inhibitor PCI-32765 and Rituximab in High-Risk Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Patients [Phase 2]
Phase 2 trial evaluating the combination of PCI-32765 (ibrutinib) and rituximab in high-risk chronic lymphocytic leukemia and small lymphocy…
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: Ofatumumab-based Induction Chemoimmunotherapy in Previously Untreated Patients With CLL/SLL [Phase 2]
Phase 2 trial evaluating ofatumumab-based induction chemoimmunotherapy in previously untreated chronic lymphocytic leukemia/small lymphocyti…
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: Sapacitabine, Cyclophosphamide, Rituximab for Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma (CLL/SLL) With Deletion (11q22-23) [Phase 2]
Phase 2 trial investigating sapacitabine with cyclophosphamide and rituximab for relapsed CLL/SLL with 11q deletion; study terminated with r…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: An Extension Study for Subjects Who Are Deriving Benefit With Idelalisib (GS-1101; CAL-101) Following Completion of a Prior Idelalisib Study [Phase 1, Phase 2]
An extension study of idelalisib (GS-1101) in subjects who benefited from prior idelalisib therapy; study terminated with results posted in …
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CLINICAL_TRIALS trial_result · 2019-08-26Clinical Trial Update: Alternating Thalidomide and Lenalidomide Therapy Plus Rituximab (ThRiL) as Initial Treatment for Patients With CLL [Phase 2]
Phase 2 clinical trial evaluating alternating thalidomide and lenalidomide therapy plus rituximab (ThRiL) as initial treatment for chronic l…
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CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: Extension Study of Idelalisib in Participants With Chronic Lymphocytic Leukemia (CLL) Who Participated in GS-US-312-0116 (NCT01539512) [Phase 3]
Extension study update for idelalisib in chronic lymphocytic leukemia participants from a prior phase 3 trial; study terminated with results…
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CLINICAL_TRIALS trial_result · 2019-08-16Clinical Trial Update: A Prospective Cohort of Obinutuzumab and Chlorambucil (GC) Chemotherapy for the Treatment of Elderly Patients With Chronic Lymphocytic Leukemia Including Next- Generation Sequencing (NGS)-Based Assessment [Phase 2]
Phase 2 clinical trial evaluating obinutuzumab and chlorambucil (GC) chemotherapy for elderly chronic lymphocytic leukemia patients, with NG…
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CLINICAL_TRIALS trial_result · 2019-08-14Clinical Trial Update: A Study of Dasatinib and Rituximab for Relapsed/Refractory Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
Clinical trial update for dasatinib plus rituximab in relapsed/refractory chronic lymphocytic leukemia; study terminated with results posted…