Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL [Phase 2]
Phase 2 trial evaluating a combination of zanubrutinib, obinutuzumab, and sonrotoclax in previously untreated chronic lymphocytic leukemia a…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Zanubrutinib in Patients With Waldenström's Macroglobulinemia, Chronic Lymphocytic Leukemia, Marginal Zone Lymphoma and Follicular Lymphoma
This clinical trial update reports that recruitment is ongoing for a study evaluating zanubrutinib in patients with Waldenström's macroglobu…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19 [Phase 1]
A Phase 1 clinical trial update describing CD19-targeted CAR T-cell immunotherapy for high-risk or relapsed CD19+ acute lymphoblastic leukem…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Safety Study of CC312 in Adult Patients With Relapsed/Refractory CD19 Positive B-cell Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 safety study of CC312 in adults with relapsed/refractory CD19-positive B-cell hematologic mal…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors [NA]
A recruiting clinical trial evaluating implanted loop recorders to detect and manage arrhythmias in patients receiving Bruton tyrosine kinas…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Global Trial in APG2575 for Patients With CLL/SLL [Phase 3]
Global Phase 3 trial of APG2575 in chronic lymphocytic leukemia and small lymphocytic lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-cell Malignancies [Phase 1, Phase 2]
GT719 Injection is being studied in a Phase 1/2 trial for recurrent or refractory CD19-positive adult B-cell malignancies, with recruitment …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation [Phase 1]
Phase 1 trial evaluating Zanubrutinib in combination with Odronextamab for Richter transformation in transformed chronic lymphocytic leukemi…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment
This clinical trial update describes a study assessing vaccine responses in patients who previously received CAR-T therapy for multiple myel…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas [Phase 1]
This entry provides an update on an ongoing Phase 1 trial of CD19-targeted CAR T-cells (CD19.20.22) for relapsed/refractory B-cell lymphomas…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Clinico-hematological and Molecular Characteristics of Chronic Lymphocytic Leukemia Patients
Clinical trial update describing clinico-hematological and molecular characteristics of Chronic Lymphocytic Leukemia patients; the study is …
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 clinical trial update describes modified CD19/CD20 CAR-T cells for recurrent or refractory B-cell lymphoma or chronic lymphocytic …
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL [Phase 3]
Phase 3 trial comparing acalabrutinib with obinutuzumab and venetoclax versus obinutuzumab and venetoclax in previously untreated high-risk …
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: LP-168 and Obinutuzumab for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Variants of This [Phase 2]
Phase 2 trial evaluating LP-168 in combination with obinutuzumab for chronic lymphocytic leukemia/small lymphocytic lymphoma and related var…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies [Phase 1, Phase 2]
Clinical trial update on CLIC-1901 for relapsed/refractory CD19-positive hematologic malignancies (Phase 1/Phase 2), currently recruiting.
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Acalabrutinib in Combination With ACP-319, for Treatment of Chronic Lymphocytic Leukemia [Phase 1]
This clinical trial update describes a Phase 1 study of acalabrutinib in combination with ACP-319 for Chronic Lymphocytic Leukemia. The tria…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Anti CD19 CAR-T Combined With BTKi to Treat Newly Diagnosed High-risk CLL/SLL [NA]
This clinical trial update describes a study evaluating the combination of anti-CD19 CAR-T therapy with a BTK inhibitor to treat newly diagn…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia
A clinical trial evaluating the role of SF3B1 mutation in assessing acute lymphoblastic leukemia and chronic lymphocytic leukemia; the study…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Phase I Dose Finding Study of MB-CART2219.1 [Phase 1]
This clinical trial update reports that a Phase I dose-finding study of MB-CART2219.1 is currently recruiting at University Hospital Tuebing…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated With Pirtobrutinib After Previous Treatment With Zanubrutinib [Phase 2]
A Phase 2 clinical trial examines clonal dynamics in chronic lymphocytic leukemia patients treated with pirtobrutinib after prior zanubrutin…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: 64Cu-LLP2A for Imaging Hematologic Malignancies [EARLY_Phase 1]
Phase 1 imaging trial evaluating 64Cu-LLP2A in hematologic malignancies is currently recruiting, targeting multiple myeloma and various lymp…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Assesment of the Immune Response to RSV Vaccine in Patients With Myeloma, Lymphoma and Hematological Leukemia
This clinical trial update assesses the immune response to an RSV vaccine in patients with hematologic cancers, including multiple myeloma, …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia [Phase 1]
This clinical trial update announces a Phase 1 study of CAP-100 for relapsed/refractory chronic lymphocytic leukemia and small lymphocytic l…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: A Study of Clinical Outcomes in Chronic Lymphocytic Leukemia (CLL) Patients Treated With Venetoclax in Greece
This is a clinical trial update for a study of venetoclax in Chronic Lymphocytic Leukemia conducted in Greece. The study is currently active…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Study Venetoclax Effectiveness and Real-Life Treatment Management in Participants With Chronic Lymphocytic Leukemia
This clinical trial update discusses venetoclax effectiveness and real-life treatment management in chronic lymphocytic leukemia, with the s…