Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency [NA]
A Mayo Clinic-sponsored clinical trial evaluates cholecalciferol (vitamin D3) for improving survival in patients with newly diagnosed cancer…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma [Phase 1]
A Phase 1 trial is evaluating the combination of copanlisib and nivolumab in patients with Richter's transformation or transformed indolent …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia [Phase 2]
A phase 2 clinical trial evaluating the combination of acalabrutinib and obinutuzumab for Chronic Lymphocytic Leukemia and Small Lymphocytic…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of DZD8586 Combination in CLL/SLL (TAI-SHAN10) [Phase 2]
This clinical trial update notes that a Phase 2 study of DZD8586 in combination therapy for chronic lymphocytic leukemia and small lymphocyt…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial evaluating venetoclax in relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma is curren…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers. [Phase 1, Phase 2]
BeiGene reports a Phase 1/2 trial evaluating the safety of novel dose ramp-up schedules for Sonrotoclax in chronic lymphocytic leukemia; the…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial evaluating acalabrutinib for chronic lymphocytic leukemia and small lymphocytic lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Precision Physical Exercise for Personalized Onco-Hematology. [NA]
An update on a clinical trial evaluating precision physical exercise for personalized management in onco-hematology, spanning hematologic ca…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation [Phase 2]
A Phase 2 clinical trial is evaluating a triple therapy consisting of lisocabtagene maraleucel, nivolumab, and ibrutinib for Richter transfo…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Mosunetuzumab for CLL MRD Clearance [Phase 1, Phase 2]
Clinical trial update for mosunetuzumab in chronic lymphocytic leukemia focusing on measurable residual disease clearance in Phase 1/2 studi…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma [Phase 1]
An ongoing Phase 1 clinical trial update for AS-1763 in adults with previously treated B-cell malignancies, including chronic lymphocytic le…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: ALICIA (Acalabrutinib in CLL Therapy)
Clinical trial update for the ALICIA study evaluating acalabrutinib in chronic lymphocytic leukemia; the study status is active but not recr…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
An ongoing clinical trial investigating muscle dysfunction in patients with hematologic diseases referred for stem cell transplantation.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Study of the Use of Venetoclax in Participants With Chronic Lymphocytic Leukemia (CLL) Under Real-Life Setting
A real-world study evaluating venetoclax in patients with chronic lymphocytic leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Zanubrutinib and Venetoclax in CLL (ZANU-VEN) [Phase 2]
A Phase 2 clinical trial (ZANU-VEN) evaluating the combination of zanubrutinib and venetoclax for chronic lymphocytic leukemia and small lym…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Innovative Biomarkers of Cardiovascular Complications Associated With Second-generation Bruton Tyrosine Kinase Inhibitor Treatments: a Single-center Cohort Study
A single-center cohort study is assessing biomarkers of cardiovascular complications in patients treated with second-generation BTK inhibito…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers [Phase 2]
A Phase 2 clinical trial evaluating nicotinamide in patients with chronic lymphocytic leukemia who have a history of non-melanoma skin cance…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: French Observational Study of Patients With Chronic Lymphocytic Leukemia Or Small Lymphocytic Lymphoma in Real-World Settings
A French observational study of patients with chronic lymphocytic leukemia or small lymphocytic lymphoma in real-world settings is ongoing b…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Prospective Observational Trial to Assess Treatment Sequences and Factors That Impact Overall Sur-vival in Patients With Chronic Lymphocytic Leukaemia (CLL) Treated Within First-line Studies of the GCLLSG
A prospective observational trial by the German CLL Study Group to assess treatment sequences and factors that impact overall survival in pa…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Retention Rate of Acalabrutinib in a Non-interventional Setting
A non-interventional study update evaluating how long patients with chronic lymphocytic leukemia stay on acalabrutinib in real-world use.
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: DZD8586 in Patients With Relapsed or Refractory CLL/SLL (TAI-SHAN8) [Phase 2]
A Phase 2 clinical trial evaluating DZD8586 in patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma …
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Evaluation of the Safety and Efficacy of the Association of Ibrutinib and Daratumumab in Relapsed/Refractory Chronic Lymphocytic Leukemia With p53 Dysfunction [Phase 2]
Clinical trial evaluates the safety and efficacy of combining ibrutinib with daratumumab in relapsed/refractory chronic lymphocytic leukemia…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma [Phase 1]
This clinical trial update describes a Phase 1 study of pevonedistat in combination with ibrutinib for relapsed or refractory chronic lympho…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)
This clinical trial update describes an in vivo metabolic profiling study for Chronic Lymphocytic Leukemia led by University of Wisconsin–Ma…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Venetoclax as Consolidation in CLL Patients Treated With BTK Inhibitor Monotherapy [Phase 2]
A Phase 2 trial is evaluating venetoclax as consolidation therapy in chronic lymphocytic leukemia or small lymphocytic lymphoma patients on …