Chronic Lymphocytic Leukemia
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: Observational Study in CLL Patients Receiving BR
This entry notes the completion of an observational study in chronic lymphocytic leukemia patients treated with the BR regimen (bendamustine…
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: A Phase I Study of AC0010 in Patients With CLL/ SLL, MCL, DLBCL and Other NHL [Phase 1]
Phase I trial evaluating AC0010 in patients with CLL/SLL, mantle cell lymphoma, diffuse large B-cell lymphoma, and other non-Hodgkin lymphom…
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer [NA]
Clinical trial update on caregiver-delivered massage therapy to improve quality of life in pediatric cancer patients; the study (NCT01053494…
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion) [Phase 1, Phase 2]
Phase 1/2 study investigating Antiminor Histocompatibility Complex (MiHA) T cells in patients with relapsed hematologic malignancies after m…
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CLINICAL_TRIALS research · 2017-08-10Clinical Trial Update: Analysis of Genetic Factors Related to Predisposition and Prognosis of Hematological Malignancies in Israel
A completed Israeli clinical trial analyzing genetic factors associated with predisposition and prognosis of hematologic malignancies, inclu…
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CLINICAL_TRIALS research · 2017-08-04Clinical Trial Update: Humanized CAR-T Therapy for Treatment of B Cell Malignancy [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a humanized CAR-T cell therapy for chronic lymphocytic leukemia (a B-cell leukemia).
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: Study of Safety,Efficacy and Pharmacokinetics of CT-1530 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's Macroglobulinemia [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of CT-1530 in relapsed or refractory B-cell non-Hodgkin lymphoma, chronic lymphocyt…
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: A Study of Anti-CD19 CAR-T Cell Immunotherapy for Refractory /Relapsed B Cell Malignancies [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/Phase 2 study of an anti-CD19 CAR-T cell therapy for refractory/relapsed B-cell malignancies…
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CLINICAL_TRIALS research · 2017-05-31Clinical Trial Update: An Observational Study Examining the Effect of Added MabThera Therapy in Patients With Untreated Chronic Lymphocytic Leukemia
This observational study evaluates adding MabThera (rituximab) therapy to initial treatment in patients with untreated chronic lymphocytic l…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomarkers in Samples From Patients With Chronic Lymphocytic Leukemia Treated on Clinical Trial ECOG-2997
A biomarker analysis update using samples from patients with chronic lymphocytic leukemia treated on the ECOG-2997 clinical trial.
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia
A clinical trial update concerning C-X-C chemokine receptor 4 in chronic lymphocytic leukemia, sponsored by Assiut University.
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CLINICAL_TRIALS research · 2017-03-16Clinical Trial Update: Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma [Phase 1, Phase 2]
This document describes a Phase 1/2 clinical trial evaluating competitive transfer of two αCD19-TCRz-CAR-T cell constructs (one with CD28 an…
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CLINICAL_TRIALS research · 2017-03-13Clinical Trial Update: Ruxolitinib Combined With Ibrutinib in Chronic Lymphocytic Leukemia Patients [Phase 1, Phase 2]
This document provides an update on a Phase 1/2 clinical trial evaluating the combination of ruxolitinib and ibrutinib in patients with chro…
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CLINICAL_TRIALS research · 2016-11-02Clinical Trial Update: An Observational Study on The Health Related Quality of Life in Patients With Chronic Lymphocytic Leukaemia
This document summarizes the health-related quality of life findings from an observational study in patients with chronic lymphocytic leukem…
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CLINICAL_TRIALS research · 2016-11-01Clinical Trial Update: An Observational Study on Infusion-related Adverse Events at Administration of MabThera (Rituximab) in Patients With Chronic Lymphocytic Leukemia
An observational study assesses infusion-related adverse events during MabThera (rituximab) administration in patients with chronic lymphocy…
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CLINICAL_TRIALS research · 2016-09-07Clinical Trial Update: a Clinical Research of Sequential CAR-T Bridging HSCT in the Treatment of Relapse/Refractory B-cell Malignancies [Phase 2]
A Phase 2 clinical trial update evaluating sequential CAR-T cell therapy followed by hematopoietic stem cell transplantation for relapse/ref…
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CLINICAL_TRIALS research · 2016-08-17Clinical Trial Update: Institut Paoli Calmettes Chronic Lymphatic Leukemia Database
Clinical trial update shows Institut Paoli-Calmettes is running a database project for Chronic Lymphocytic Leukemia (B-cell) with recruitmen…
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CLINICAL_TRIALS research · 2016-07-20Clinical Trial Update: Observational Study in Participants With Chronic Lymphocytic Leukemia (CLL), Multiple Myeloma (MM) and Non-Hodgkin's Lymphoma (NHL) in Latin America
This is a completed observational study conducted in Latin America evaluating participants with chronic lymphocytic leukemia, multiple myelo…
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CLINICAL_TRIALS research · 2016-07-12Clinical Trial Update: Peptide-drug-conjugates for Personalized, Targeted Therapy of Chronic Lymphocytic Leukemia
This document provides an update on a clinical trial investigating peptide-drug-conjugates for personalized, targeted therapy in chronic lym…
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CLINICAL_TRIALS research · 2016-06-09Clinical Trial Update: CD22 Targeting CAR-T Therapy Against B Cell Hematological Malignancies [Phase 1, Phase 2]
This entry reports a phase 1/2 clinical trial of a CD22-targeted CAR-T therapy for recurrent or refractory B-cell malignancies; the status i…
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CLINICAL_TRIALS research · 2016-04-29Clinical Trial Update: Combination of Ibrutinib and As2O3 in the Treatment of CLL [Phase 3]
Phase 3 trial evaluating the combination of ibrutinib and arsenic trioxide for chronic lymphocytic leukemia; the status is currently unknown…
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CLINICAL_TRIALS research · 2016-04-20Clinical Trial Update: Thiotepa-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies [Phase 2]
Phase 2 clinical trial investigating thiotepa-based conditioning for allogeneic stem-cell transplantation in lymphoid malignancies, includin…
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CLINICAL_TRIALS research · 2016-02-04Clinical Trial Update: Protocol for the Treatment of Patients With Previously Untreated Chronic Lymphocytic Leukemia [Phase 2]
This clinical trial update outlines a Phase 2 protocol for treating patients with previously untreated chronic lymphocytic leukemia.
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19 [NA]
Clinical trial update describing CART19 therapy for relapsed and/or chemotherapy-refractory B-cell malignancies with an unknown status of th…
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CLINICAL_TRIALS research · 2015-09-29Clinical Trial Update: Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of a genetically engineered lymphocyte therapy for chemotherapy-resistant or refrac…