Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT [Phase 1]
Phase 1 trial evaluating multi-virus cytotoxic T lymphocytes engineered with CD19 chimeric receptors for CD19-positive malignancies after st…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL [Phase 1]
Phase 1 clinical trial evaluating autologous CD19-specific CAR T cells (TBI-2001) for relapsed or refractory CD19+ B-cell lymphoma, chronic …
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Allo HSCT Using RIC and PTCy for Hematological Diseases [Phase 2]
Phase 2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning and post-transplan…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies [Phase 1]
Mayo Clinic is conducting a Phase 1 clinical trial evaluating a CD19-directed CAR-T cell therapy for relapsed/refractory B-cell malignancies…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Combating Cancer-Related Fatigue: A Personalized Supportive Care Program [NA]
This clinical trial update reports a UNC Lineberger Comprehensive Cancer Center study recruiting participants for a personalized supportive …
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Time Restricted Eating in Haematological Malignancies [Phase 2]
A Phase 2 clinical trial update evaluating time-restricted eating in haematological malignancies, including chronic lymphocytic leukemia; th…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Economic Analysis of Alliance A041202 CLL Study
This document provides an economic analysis of the Alliance A041202 study in chronic lymphocytic leukemia, outlining cost-effectiveness cons…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Phase II Trial of Zanubrutinib, Obinutuzumab, Bendamustine (ZGB) as First-Line Therapy for Chronic Lymphocytic Leukemia: A Single-Center Study [Phase 2]
A Phase II clinical trial evaluating ZGB (zanubrutinib, obinutuzumab, bendamustine) as first-line therapy for chronic lymphocytic leukemia; …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: A Personalized Neoantigen Cancer Vaccine in Treatment Naïve, Asymptomatic Patients With IGHV Unmutated CLL. [Phase 1]
Phase 1 trial evaluating a personalized neoantigen cancer vaccine in treatment-naïve, asymptomatic IGHV-unmutated chronic lymphocytic leukem…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies [Phase 1, Phase 2]
IDP-121 is being studied in a Phase 1/2 trial for relapsed/refractory hematologic malignancies and is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Acalabrutinib in Patients With Chronic Lymphocytic Leukemia With Direct Oral Anticoagulation (CICERO)
An ongoing clinical trial evaluating acalabrutinib in chronic lymphocytic leukemia patients taking direct oral anticoagulants; the study is …
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: A Study to Evaluate the Safety,PK and PD of APG-2575 in Patients With Hematologic Malignancies [Phase 1]
Phase 1 study of APG-2575 by Ascentage Pharma for chronic lymphocytic leukemia and non-Hodgkin lymphoma is currently active but not recruiti…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL [Phase 1]
This clinical trial update describes a Phase 1 study of APG-2575, studied as a single agent or in combination with other therapies for chron…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: AGMT Austrian CLL (Chronic Lymphocytic Leukemia) Registry
Clinical trial update indicates ongoing recruitment for the AGMT Austrian CLL Registry, a registry study involving chronic lymphocytic leuke…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial) [NA]
A CARTIER clinical trial is evaluating cardiovascular prevention strategies in elderly cancer patients and is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Exercise As Intervention in Chronic Lymphocytic Leukemia [NA]
A clinical trial sponsored by Universidade do Porto is evaluating exercise as an intervention for Chronic Lymphocytic Leukemia and is curren…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Study on the Diagnosis and Management of CLL in Italy by GIMEMA
Ongoing Italian study by GIMEMA recruiting to improve diagnosis and management of chronic lymphocytic leukemia and related conditions (inclu…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies [Phase 1]
Phase 1 clinical trial update for BP1002 in advanced lymphoid malignancies across several B-cell and T-cell lymphomas; trial status is activ…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: A Study of Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting
This clinical trial update announces a study of lisocabtagene maraleucel for relapsed/refractory Chronic Lymphocytic Leukemia and Small Lymp…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Developing a Patient-Reported Outcome (PRO) Screening Measure for Infections and Measuring Quality of Life in Hematological Patients With Secondary Immunodeficiency (SID) Across the Treatment Trajectory - The PRO SID Project
This clinical trial update describes the PRO SID Project, which aims to develop and validate a patient-reported outcome screening measure fo…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Clinical Outcomes of Chronic Lymphocytic Leukemia (CCL) and Mantle Cell Lymphoma (MCL) Participants Treated With Ibrutinib: A Medical Chart Review From India
A retrospective medical chart review from India evaluating outcomes of chronic lymphocytic leukemia and mantle cell lymphoma patients treate…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Observational Study Relapsed or Refractory Chronic Lymphocytic Leukemia Venetoclax-based Regimens Outside Clinical Trials in Italy
Observational study assessing venetoclax-based regimens for relapsed or refractory chronic lymphocytic leukemia in Italy, outside traditiona…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Assessment of Financial Difficulty in Participants with Chronic Lymphocytic Leukemia and Multiple Myeloma
This completed clinical trial update summarizes an assessment of financial difficulty experienced by participants with chronic lymphocytic l…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update on locally manufactured CAR T-cell products for multiple B-cell malignancies, including B-cell lymphoma and B-…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Real-world Study of Acalabrutinib
A real-world study of acalabrutinib sponsored by Ruijin Hospital is enrolling by invitation, investigating its use in mantle cell lymphoma a…