Limb-threatening Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia [NA]
A clinical trial is currently recruiting to evaluate revascularization strategies for single versus multiple infrapopliteal vessels in chron…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: AcoArt Litos PCB Below-the-knee Global Trial [NA]
Recruitment is ongoing for a global trial evaluating the AcoArt Litos PCB device for treatment of chronic limb-threatening ischemia.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: The ROAMM-EHR Study [NA]
The ROAMM-EHR study, sponsored by the University of Florida, is currently recruiting. It evaluates treatment options for Peripheral Arterial…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Efficacy of the Ranger Drug-Coated Balloon in Treating BTK Lesions in Patients With CLTI
A clinical trial update reports on evaluating the Ranger Drug-Coated Balloon for below-the-knee lesions in patients with chronic limb-threat…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Intravascular Ultrasound for Peripheral Artery Disease Revascularization [NA]
This ClinicalTrials.gov update covers a study evaluating intravascular ultrasound for guiding revascularization in peripheral arterial disea…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease [NA]
This clinical trial update describes a radiotracer-based perfusion imaging study in patients with peripheral artery disease, including those…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Can a Dedicated Chronic Limb-threatening Ischaemia (CLTI) Clinic Improve Patient Self-reported Quality of Life
A completed clinical trial evaluated whether a dedicated CLTI clinic improves patients' self-reported quality of life.
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Angioplasty With Shockwave IVL Catheter System in Femoropopliteal Lesions
Clinical trial update indicates the Shockwave IVL Catheter System is currently recruiting for treatment of femoropopliteal lesions in patien…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection with Borderline Vascularity
This clinical trial update reports outcomes after surgical debridement of diabetic foot infection in patients with borderline vascularity an…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Natural Progression of High-Risk Chronic Limb-Threatening Ischemia: The CLariTI Study
The CLariTI study, sponsored by LimFlow, Inc., completed evaluation of the natural progression of high-risk chronic limb-threatening ischemi…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Observational Study Regarding the Necessity of Inclusion of Foot Arch State Together With the Angiosome Theory Within the Wound, Ischemia and Foot Infection Classification (WIfI) to Enhance the Predictability of Wound Healing and Decision Making
An observational clinical trials study from Ain Shams University evaluating whether including the foot arch state with the WIfI classificati…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: Prospective Multicenter Registry on the Endovascular Treatment in Critical Limb Threatening Ischemia With Below the Knee Lesions With Wound, Ischemia, and Foot Infection (WIFI) Assessment
A prospective multicenter registry evaluating endovascular treatment for chronic limb-threatening ischemia with below-the-knee lesions using…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Multimodal Noninvasive Assessment of Peripheral Circulation in Chronic Limb-threatening Ischemia
This clinical trial update describes a study evaluating multimodal noninvasive methods to assess peripheral circulation in people with Chron…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Agreement Study on AI-assisted Smartphone-based Monitoring Tool for Difficult-to-heal Ischemic Leg Ulcers
Clinical trial update on an AI-enabled smartphone-based monitoring tool for difficult-to-heal ischemic leg ulcers in patients with chronic l…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: PROMISE I Early Feasibility Trial of the LimFlow Stent Graft System [NA]
The PROMISE I early feasibility trial evaluated the LimFlow Stent Graft System for critical limb ischemia and chronic limb-threatening ische…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Use of CPETarm for Risk Stratification of Patients With CLTI [NA]
Clinical trial update on a University of Manchester study evaluating CPETarm for risk stratification in chronic limb-threatening ischemia; t…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia [NA]
Clinical trial update for PROMISE II evaluating percutaneous deep vein arterialization in late-stage chronic limb-threatening ischemia; stat…
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CLINICAL_TRIALS trial_result · 2022-11-30Clinical Trial Update: Bone Marrow Mononuclear Cells vs Mesenchymal Stem Cells in Diabetic Patients With Chronic Limb Ischemia [Phase 1, Phase 2]
Phase 1/2 trial comparing bone marrow mononuclear cells to mesenchymal stem cells in diabetic patients with chronic limb-threatening ischemi…
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CLINICAL_TRIALS trial_result · 2021-12-22Clinical Trial Update: Study of AMG0001 to Improve Ulcer Healing and Perfusion in Subjects With Peripheral Ischemic Ulcers [Phase 2]
Phase 2 clinical trial update for AMG0001 evaluating improvement in ulcer healing and perfusion in subjects with peripheral ischemic ulcers.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Non-Interventional Post Marketing Surveillance Study of Neovasculgen® in Patients With Chronic Lower Limb Ischemia [Phase 4]
Phase 4 non-interventional post-marketing study of Neovasculgen in patients with chronic lower limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Evaluation of Diagnostic Criteria for Chronic Critical Limb Ischemia
A completed clinical study evaluating diagnostic criteria for chronic limb-threatening ischemia, with stroke listed among the conditions.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Investigation of Safety, Pharmacokinetics and Pharmacodynamics of Different Doses of BIWH 3 in Patients With Chronic Critical Limb Ischaemia [Phase 1]
This Phase 1 study assesses safety, pharmacokinetics and pharmacodynamics of multiple doses of BIWH 3 in patients with chronic critical limb…
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CLINICAL_TRIALS trial_result · 2012-12-13Clinical Trial Update: Intra-arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI) [Phase 1, Phase 2]
A Phase 1/2 trial of intra-arterial stem cell therapy for chronic limb-threatening ischemia (CLI) conducted by UMC Utrecht has completed.
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CLINICAL_TRIALS research · 2011-07-28Clinical Trial Update: Viennese Registry on Patients With Chronic Critical Limb Ischemia
A clinical trial update for the Viennese registry studying patients with chronic critical limb ischemia and skin defects in the lower limbs;…