Chronic Kidney Disease
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis [Phase 3]
Phase 3 clinical trial update evaluating the efficacy and safety of etelcalcetide in treating secondary hyperparathyroidism in CKD patients …
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CLINICAL_TRIALS research · 2017-03-24Clinical Trial Update: Systemic Redesign and Demonstration for Early Detection, Evaluation and Management of Chronic Kidney Disease in Shanghai
A clinical trial update describing a systemic redesign and demonstration project for early detection, evaluation, and management of chronic …
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: A Study Comparing the Effects of Epoetin Hospira and Epogen/Epoetin Alfa (Amgen) When Administered IV in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment [Phase 1]
A Phase 1 study comparing intravenous epoetin alfa products from Hospira and Amgen in chronic kidney disease patients on hemodialysis receiv…
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CLINICAL_TRIALS research · 2017-03-17Clinical Trial Update: Oral Findings in Chronic Kidney Disease
This entry reports an ongoing clinical trial examining oral findings in individuals with chronic kidney disease, with the study status curre…
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CLINICAL_TRIALS research · 2017-03-17Clinical Trial Update: Topical Magnesium and Muscle Cramps in Dialysis Patients. [Phase 2]
Phase 2 clinical trial assessing the use of topical magnesium to reduce muscle cramps in patients with chronic kidney disease and end-stage …
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CLINICAL_TRIALS research · 2017-03-17Clinical Trial Update: Inspiratory Muscle Training in Chronic Kidney Disease [NA]
A status update on a clinical trial evaluating inspiratory muscle training for patients with chronic kidney disease; the current study statu…
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Vitamin D 2 to Dialysis Patients
Clinical trial update indicates that the Vitamin D2 study in dialysis patients has been terminated.
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: Correction of Zinc Deficiency in Children With Chronic Kidney Disease and Kidney Transplant [Phase 3]
Phase 3 clinical trial evaluating zinc supplementation to correct zinc deficiency in children with chronic kidney disease and after kidney t…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: A Study to Evaluate the Blood Levels, Safety, and Tolerability of PF-00734200 in Subjects With Impaired Kidney Function and Normal Kidney Function [Phase 1]
Phase 1 study assessing blood levels, safety, and tolerability of PF-00734200 in subjects with impaired kidney function and in those with no…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Prevention of Renal and Vascular Endstage Disease Intervention Trial [Phase 3]
A Phase 3 trial focused on preventing end-stage renal disease and vascular complications has completed.
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Autonomic Dysfunction and Inflammation in Chronic Hemodialysis Patients
This completed clinical trial investigated autonomic dysfunction and inflammation in patients receiving chronic hemodialysis.
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FDA approval · 2017-03-09FDA Approved: PARICALCITOL — Original Application (Amneal Pharmaceuticals LLC)
FDA approved Amneal Pharmaceuticals LLC's original ANDA for PARICALCITOL, a generic paricalcitol product for treating secondary hyperparathy…
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CLINICAL_TRIALS research · 2017-03-08Clinical Trial Update: Prevalence of Oral Findings in Chronic Kidney Disease
An update on a clinical trial investigating the prevalence of oral findings in people with chronic kidney disease.
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Acute Effects of Intradialytic Exercise on Cardiovascular Function in Hemodialysis Patients [NA]
A completed clinical trial assessing the acute cardiovascular effects of intradialytic exercise in patients undergoing hemodialysis.
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Exercise as an Adjunct Therapy to Reduce Blood Pressure in Chronic Kidney Disease [NA]
A clinical trial evaluating exercise as an adjunct therapy to reduce blood pressure in adults with chronic kidney disease and hypertension h…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: A Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes Mellitus [Phase 2]
A Phase 2 clinical trial of RTA 402 (bardoxolone methyl) in patients with chronic kidney disease and type 2 diabetes was terminated.
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: A Glomerular Filtration Rate (GFR) Measuring Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes Mellitus [Phase 2]
The Phase 2 study evaluating RTA 402 (bardoxolone methyl) for measuring glomerular filtration rate in chronic kidney disease patients with t…
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FDA approval · 2017-03-01FDA Approved: FARXIGA — Supplemental Application (AstraZeneca Pharmaceuticals LP)
The FDA approved a supplemental application for Farxiga (dapagliflozin) from AstraZeneca Pharmaceuticals LP. This action updates the drug's …
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Development of a New Non-radioactive Test for Measuring Glomerular Filtration Rate Using the Tetrapeptide N-acetyl-Ser-Asp-Lys-Pro-amide (AcSDKP-NH2) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a non-radioactive test for measuring glomerular filtration rate using AcSDKP-NH2 has completed.
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Growth Hormone Treatment in Infants Aged 1 to 2 Years With Chronic Renal Insufficiency (CRI) and Growth Retardation. [Phase 4]
A Phase 4 trial evaluating growth hormone treatment in infants aged 1 to 2 years with chronic kidney disease or chronic renal insufficiency …
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Assessing Manual Components of Brazilian Children and Adolescents on Hemodialysis
The trial investigating manual components for Brazilian children and adolescents on hemodialysis has completed.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: A Study of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus With Chronic Kidney Disease or Kidney Failure on Dialysis (MK-3102-019) [Phase 3]
Phase 3 study of Omarigliptin (MK-3102) in people with type 2 diabetes and chronic kidney disease or dialysis; trial completed and results p…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Uric Acid and the Endothelium in CKD [NA]
A completed clinical trial investigating the relationship between uric acid and endothelial function in chronic kidney disease. Results were…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Educational Programme Impact on Serum Phosphate Control [NA]
A completed clinical trial assessed whether an educational program improves serum phosphate control in people with chronic kidney disease.
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CLINICAL_TRIALS safety_alert · 2017-02-16Clinical Trial Update: Proton Pump Inhibitor Use is Associated With High Risk of Pneumonia in Chronic Kidney Disease Patients
A clinical trial update reports that proton pump inhibitor use is associated with a higher risk of pneumonia in patients with chronic kidney…