Chronic Kidney Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Long-Term Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Hypertension and Kidney Disease [Phase 3]
Phase 3 trial evaluating long-term safety of azilsartan medoxomil with chlorthalidone versus olmesartan medoxomil with hydrochlorothiazide i…
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CLINICAL_TRIALS trial_result · 2013-12-11Clinical Trial Update: Effect of the Synbiotic Probinul-Neutro® on Gastrointestinal Symptoms and Plasma p-Cresol Level in Chronic Renal Failure [Phase 4]
Phase 4 trial evaluating the synbiotic Probinul-Neutro on gastrointestinal symptoms and plasma p-Cresol levels in chronic kidney disease; th…
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CLINICAL_TRIALS research · 2013-12-09Clinical Trial Update: Vitamin D Supplementation and Cardiac Hypertrophy in Chronic Kidney Disease (CKD) [Phase 2, Phase 3]
This document provides an update on a Phase 2/Phase 3 clinical trial investigating whether Vitamin D supplementation affects cardiac hypertr…
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CLINICAL_TRIALS trial_result · 2013-12-09Clinical Trial Update: Impact of Vitamin D on Endothelial Function and Blood Biomarkers Including CD28 Null Cells in CKD [Phase 3]
A Phase 3 clinical trial update reporting completion of a study evaluating the effects of Vitamin D on endothelial function and blood biomar…
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CLINICAL_TRIALS research · 2013-12-06Clinical Trial Update: Renal Protection Using Sympathetic Denervation in Patients With Chronic Kidney Disease [Phase 2]
Phase 2 clinical trial update on renal protection in chronic kidney disease using sympathetic denervation. Conditions include hypertension a…
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CLINICAL_TRIALS research · 2013-12-03Clinical Trial Update: Effects of Low Protein Formula on Renal Function, Oxidative Stress and Antioxidant Capacities in CKD Patients [NA]
This clinical trial update examines whether a low-protein formula influences renal function, oxidative stress, and antioxidant capacity in p…
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CLINICAL_TRIALS research · 2013-11-28Clinical Trial Update: Canadian Study of Prediction of Risk and Evolution to Dialysis, Death and Interim Cardiovascular Events Over Time
This clinical trial update describes a Canadian study that aims to predict the risk and progression of chronic kidney disease toward dialysi…
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Paricalcitol on Albuminuria, Inflammation and Fibrosis on Proteinuric Chronic Renal Diseases (PALIFE Study) [Phase 4]
A Phase 4 PALIFE trial evaluating paricalcitol for albuminuria, inflammation, and fibrosis in proteinuric chronic kidney disease has been te…
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FDA approval · 2013-11-27FDA Approved: VELPHORO — Original Application (Fresenius Medical Care Renal Therapies Group, LLC)
FDA approved Velphoro (sucroferric oxyhydroxide) under an original NDA for the treatment of hyperphosphatemia in adults with chronic kidney …
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: LEARN-6™: A Prospective, Observational Nursing Home Study
LEARN-6 is a completed prospective observational nursing home study; results were posted in 2013 and involve anemia and chronic kidney disea…
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CLINICAL_TRIALS trial_result · 2013-11-14Clinical Trial Update: Open-label Pharmacokinetic Study of Iron Isomaltoside 1000 (Monofer®) Administered by 500 mg IV Bolus Injection or 1000 mg Intravenous to Patients With CKD [Phase 1]
Open-label Phase 1 pharmacokinetic study evaluating iron isomaltoside 1000 (Monofer) given as a 500 mg IV bolus or 1000 mg IV infusion in no…
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease [Phase 3]
A Phase 3 trial evaluating the effect of vitamin D3 supplementation on inflammation markers in high-risk cardiovascular patients with chroni…
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CLINICAL_TRIALS research · 2013-11-11Clinical Trial Update: Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients [Phase 4]
Phase 4 clinical trial comparing an egg albumin-based protein supplement with a renal-specific protein supplement in hemodialysis patients t…
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CLINICAL_TRIALS trial_result · 2013-11-08Clinical Trial Update: Evaluation of the Safety and Efficacy of Insulin Glargine + Glulisine or Insulin Regular + NPH Insulin (Isophane Insulin) Use in Type 2 Diabetes Mellitus Patients With Moderate Renal Failure. [Phase 4]
A Phase 4 trial evaluating the safety and efficacy of two insulin regimens in Type 2 diabetes patients with moderate renal impairment: insul…
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CLINICAL_TRIALS trial_result · 2013-11-05Clinical Trial Update: A Study of Once-Monthly Subcutaneous Mircera for the Treatment of Chronic Renal Anemia in Pre-Dialysis Patients Not Currently Treated With ESA. [Phase 3]
Phase 3 study evaluating once-monthly subcutaneous Mircera for chronic renal anemia in pre-dialysis patients not currently treated with eryt…
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathy [Phase 2]
A Phase 2 multicenter, double-blind, placebo-controlled study evaluating atrasentan, including thoracic bioimpedance, in adults with type 2 …
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: Study to Assess Pegloticase (KRYSTEXXA®) in Patients on Hemodialysis [Phase 1]
Phase 1 study evaluating pegloticase (KRYSTEXXA) in patients on hemodialysis due to chronic kidney disease; the trial has completed.
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FDA approval · 2013-10-17FDA Approved: ZEMPLAR — Supplemental Application (AbbVie Inc.)
FDA approved a supplemental application for ZEMPLAR (paricalcitol) submitted by AbbVie Inc., indicating an approved update to its labeling/i…
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CLINICAL_TRIALS safety_alert · 2013-10-16Clinical Trial Update: Renal Toxicity of Iodixanol and Iopromide in Patients With Renal Dysfunction [Phase 4]
Phase 4 trial update evaluating renal toxicity risk of iodixanol and iopromide in patients with chronic kidney disease.
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CLINICAL_TRIALS withdrawal · 2013-10-10Clinical Trial Update: The Effects of Dietary Phosphate Intake on Calciotropic Hormones and FGF23. [NA]
A clinical trial evaluating the effects of dietary phosphate intake on calciotropic hormones and FGF23 was withdrawn; the study included hea…
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CLINICAL_TRIALS trial_result · 2013-10-09Clinical Trial Update: Phosphate Intake's Effect on the Skeletal System - Pilot [NA]
A pilot clinical trial evaluating the effect of phosphate intake on the skeletal system has completed, including healthy individuals and par…
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CLINICAL_TRIALS trial_result · 2013-09-27Clinical Trial Update: Metabolic Effects of Paricalcitol [Phase 2]
Phase 2 trial assessing metabolic effects of paricalcitol in chronic kidney disease; the study has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2013-09-27Clinical Trial Update: Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease [Phase 2, Phase 3]
A randomized controlled trial of Vitamin D3 for diabetic kidney disease has completed Phase 2/3 studies, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: Effect of Febuxostat on Renal Function in Patients With Gout and Moderate to Severe Renal Impairment [Phase 2]
Phase 2 trial evaluating the effect of febuxostat on renal function in patients with gout and moderate to severe renal impairment; results p…
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: Effect of Remote Ischaemic Preconditioning on Renal Function in Patients Undergoing Living Donor Kidney Transplantation [NA]
A completed trial evaluated whether remote ischemic preconditioning could improve renal function in living donor kidney transplant recipient…