Chemotherapy-induced Nausea and Vomiting
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CLINICAL_TRIALS trial_result · 2021-06-25Clinical Trial Update: Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy [NA]
Clinical trial update on acupressure for controlling nausea in pediatric patients undergoing highly emetogenic chemotherapy; study completed…
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CLINICAL_TRIALS trial_result · 2021-06-03Clinical Trial Update: Granisetron Transdermal Patch for Prophylaxis of Delayed CINV [Phase 3]
Phase 3 clinical trial update for granisetron transdermal patch intended to prevent delayed chemotherapy-induced nausea and vomiting (CINV).
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: Acupuncture for Chemotherapy-Induced Nausea and Vomiting [NA]
Clinical trial update on acupuncture for chemotherapy-induced nausea and vomiting has completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-12-07Clinical Trial Update: PK/PD Study of Netupitant and Palonosetron in Pediatric Patients for Prevention of Chemotherapy-induced Nausea and Vomiting [Phase 2]
Phase 2 PK/PD study in pediatric patients evaluating netupitant and palonosetron for prevention of chemotherapy-induced nausea and vomiting;…
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CLINICAL_TRIALS trial_result · 2020-10-09Clinical Trial Update: Palonosetron and Dexamethasone With or Without Dronabinol in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy For Cancer [Phase 3]
Phase 3 trial evaluating palonosetron and dexamethasone with or without dronabinol for prevention of chemotherapy-induced nausea and vomitin…
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CLINICAL_TRIALS trial_result · 2020-08-19Clinical Trial Update: Feasibility of Olanzapine at REduced doSe in hIGHly Emetogenic chemoTherapy [Phase 3]
Phase 3 trial assessing feasibility of olanzapine at reduced dose for highly emetogenic chemotherapy; completed.
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CLINICAL_TRIALS trial_result · 2020-07-29Clinical Trial Update: Crossover Study Comparing Ondansetron Orally Dissolving Film Strip (ODFS) With Zofran Orally Disintegrating Tablets [Phase 1, Phase 2]
Phase 1/2 crossover trial comparing ondansetron orally dissolving film strip (ODFS) to Zofran orally disintegrating tablets for postoperativ…
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CLINICAL_TRIALS trial_result · 2020-06-12Clinical Trial Update: the Efficacy and Safety of 5-HT3 Receptor Antagonist, Dexamethasone or Megestrol Acetate Dispersible Tablets in the Control of Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of a 5-HT3 receptor antagonist, dexamethasone, or dispersible tablets of megestrol…
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: A Study to Assess the Safety and the Efficacy of IV Fosnetupitant/Palonosetron (260 mg/0.25 mg) Combination Compared to Oral Netupitant/Palonosetron (300 mg/0.5 mg) Combination for the Prevention of CINV in AC Chemotherapy in Women With Breast Cancer [Phase 3]
Phase 3 trial comparing IV fosnetupitant/palonosetron to oral netupitant/palonosetron for prevention of chemotherapy-induced nausea and vomi…
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CLINICAL_TRIALS trial_result · 2020-04-07Clinical Trial Update: Olanzapine for Prevention of Chemotherapy-induced Nausea and Vomiting in Children: A Multi-Centre Feasibility Study [Phase 2]
A Phase 2 feasibility study assessing olanzapine for preventing chemotherapy-induced nausea and vomiting in children has completed with resu…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Dexamethasone-sparing Approach Including NEPA Against Emesis Caused by Cisplatin [Phase 3]
Phase 3 trial investigating a dexamethasone-sparing approach including NEPA for chemotherapy-induced nausea and vomiting due to cisplatin.
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CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: "Olanzapine for Prevention of Chemotherapy Induced Nausea and Vomiting in Children and Adolescents Receiving Highly Emetogenic Chemotherapy (HEC)" [Phase 3]
Phase 3 trial evaluating olanzapine for prevention of chemotherapy-induced nausea and vomiting in children and adolescents receiving highly …
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CLINICAL_TRIALS trial_result · 2019-05-09Clinical Trial Update: Combination of Netupitant and Palonosetron (Akynzeo®) in the Treatment of Refractory CINV [Phase 2]
A Phase 2 trial evaluating a combination of netupitant and palonosetron (Akynzeo) for refractory chemotherapy-induced nausea and vomiting ha…
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CLINICAL_TRIALS trial_result · 2019-03-12Clinical Trial Update: Dose-finding Study of APD403 to Prevent Nausea and Vomiting After Chemotherapy [Phase 2]
Phase 2 dose-finding study of APD403 for prevention of nausea and vomiting after chemotherapy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: NEPA to Prevent Chemotherapy Induced Nausea and Vomiting in Patients With Breast Cancer [Phase 2]
Phase 2 clinical trial update evaluating NEPA to prevent chemotherapy-induced nausea and vomiting in breast cancer patients (completed).
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: An Efficacy and Safety Study of Intravenous Palonosetron Administered as an Infusion and as a Bolus for the Prevention of Nausea and Vomiting [Phase 3]
Phase 3 trial evaluating intravenous palonosetron given as an infusion versus a bolus for prevention of chemotherapy-induced nausea and vomi…
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: A Safety Study of Intravenous Pro-Netupitant and Palonosetron Combination for the Prevention of Nausea and Vomiting [Phase 3]
Complete Phase 3 safety study evaluating intravenous netupitant (Pro-Netupitant) in combination with palonosetron for prevention of chemothe…
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: Efficacy and Safety Study of Fosaprepitant (MK-0517) Plus Ondansetron Versus Ondansetron Alone for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Participants (MK-0517-044) [Phase 3]
Phase 3 trial evaluating fosaprepitant with ondansetron versus ondansetron alone for preventing chemotherapy-induced nausea and vomiting in …
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CLINICAL_TRIALS trial_result · 2018-01-17Clinical Trial Update: A Study Of IV Casopitant For The Prevention Of Chemotherapy Induced Nausea And Vomiting. [Phase 3]
Phase 3 trial update for IV casopitant aiming to prevent chemotherapy-induced nausea and vomiting; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: Study of the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Fosaprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Children (MK-0517-029) [Phase 2]
Phase 2 clinical trial evaluating pharmacokinetics, pharmacodynamics, safety, and tolerability of fosaprepitant for preventing chemotherapy-…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: To Investigate the Effect of Intravenous Ondansetron on Cardiac Conduction as Compared to Placebo and Moxifloxacin in Healthy Adult Subjects [Phase 1]
Phase 1 study evaluating the effect of intravenous ondansetron on cardiac conduction compared with placebo and moxifloxacin in healthy adult…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: A Study to Assess the Safety & Interaction Between GW679769, Dexamethasone, & Ondansetron When Taken by Healthy Adults [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating safety and potential interactions among GW679769, dexamethas…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: A Study of the Drug Casopitant for the Prevention of Nausea Caused By Cisplatin-Based Highly Emetogenic Chemotherapy [Phase 3]
A Phase 3 trial evaluating casopitant to prevent nausea and vomiting caused by cisplatin-based chemotherapy has completed.
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: A Study Testing the Effect and Safety of Casopitant (GW679769) While Taking Warfarin in Healthy Human Volunteers [Phase 1]
A Phase 1 study evaluated the effect and safety of the antiemetic casopitant (GW679769) when co-administered with warfarin in healthy volunt…
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: The Effects Of GW679769 (Casopitant) On The Pharmacokinetics Of Docetaxel In Subjects With Cancer [Phase 1]
Phase 1 study evaluating the pharmacokinetic interaction between casopitant and docetaxel in cancer patients; the trial is completed.