Cervical Intraepithelial Neoplasia

CLINICAL_TRIALS trial_result · 2022-08-12

Clinical Trial Update: Efficacy and Safety of Cevira® in Patients With Cervical Histologic High-grade Squamous Intraepithelial Lesions (HSIL) [Phase 3]

Phase 3 trial update on efficacy and safety of Cevira in cervical HSIL (CIN2/3). Status not disclosed.

CLINICAL_TRIALS trial_result · 2022-07-13

Clinical Trial Update: An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3) [Phase 1, Phase 2]

Phase 1/2 exploratory study evaluating safety and immunogenicity of HPV16+ immunotherapy VB10.16 in women with high-grade cervical intraepit…

CLINICAL_TRIALS trial_result · 2022-06-29

Clinical Trial Update: Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female [Phase 4]

Phase 4 trial update assessing lot consistency of recombinant HPV bivalent vaccine in healthy girls aged 9-14; study completed.

CLINICAL_TRIALS trial_result · 2022-02-23

Clinical Trial Update: Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia [EARLY_Phase 1]

A completed early-phase trial evaluated the safety and potential activity of topical 5-fluorouracil and imiquimod in high-grade cervical int…

CLINICAL_TRIALS trial_result · 2021-09-08

Clinical Trial Update: A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects

A post-marketing surveillance study assessing the safety of GSK's HPV vaccine in female Chinese participants has completed with results post…

CLINICAL_TRIALS trial_result · 2021-04-02

Clinical Trial Update: Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3) [Phase 1]

A Phase 1 trial of intravaginal artesunate for HPV-positive high-grade cervical intraepithelial neoplasia (CIN2/3) has completed and results…

CLINICAL_TRIALS trial_result · 2020-12-19

Clinical Trial Update: Safety and Protective Effect Study of GSK Biologicals' Human Papillomavirus (Types 16, 18) Vaccine, Adsorbed (GSK580299) in Healthy Female Subjects From the HPV-039 Study [Phase 4]

Phase 4 trial update assessing safety and protective effect of GSK's HPV vaccine (types 16/18) in healthy females; completed with results po…

CLINICAL_TRIALS trial_result · 2020-11-30

Clinical Trial Update: DNA Methylation Testing for the Screening of Uterine Cervical Lesion [Phase 3]

Phase 3 trial update on DNA methylation testing for screening cervical lesions, investigating cervical cancer and cervical intraepithelial n…

CLINICAL_TRIALS trial_result · 2020-11-05

Clinical Trial Update: Impact on Disease Relapse of HPV Vaccination in Women Treated With LEEP for Cervical Intraepithelial Neoplasia. HOPE9 [Phase 3]

Phase 3 trial evaluating whether HPV vaccination reduces disease relapse in women treated with LEEP for cervical intraepithelial neoplasia.

CLINICAL_TRIALS research · 2020-08-10

Clinical Trial Update: FASTER-Tlalpan Study in Mexico: HPV Vaccination Impact on Cervical Cancer Screening Program [Phase 4]

Phase 4 trial update on HPV vaccination impact within a cervical cancer screening program in Mexico.

CLINICAL_TRIALS trial_result · 2020-05-04

Clinical Trial Update: A Study to Evaluate the Immunogenicity, Safety and Tolerability of Quadrivalent Human Papillomavirus Vaccine (V501) in Chinese Girls Aged 9-19 Years and Young Women Aged 20-26 Years (V501-213) [Phase 3]

Phase 3 study evaluating the immunogenicity, safety and tolerability of the quadrivalent HPV vaccine V501 in Chinese girls aged 9-19 and you…

CLINICAL_TRIALS trial_result · 2020-02-24

Clinical Trial Update: Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine [Phase 3]

Phase 3 study evaluating efficacy and immunogenicity of a recombinant HPV bivalent vaccine targeting types 16/18; trial completed.

CLINICAL_TRIALS trial_result · 2019-10-18

Clinical Trial Update: Cryotherapy vs. LEEP to Treat Cervical Intraepithelial Neoplasia (CIN) 2/3 Among HIV-positive Women [NA]

Clinical trial comparing Cryotherapy versus LEEP for CIN 2/3 in HIV-positive women has completed with results posted.

CLINICAL_TRIALS trial_result · 2019-07-08

Clinical Trial Update: Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1) [Phase 2]

Phase 2 clinical trial investigating aminolevulinic acid photodynamic therapy for HPV-positive low-grade cervical intraepithelial neoplasia …

CLINICAL_TRIALS trial_result · 2019-06-12

Clinical Trial Update: Aminolaevulinic Acid Photodynamic Therapy of Cervical Persistent HPV Infection and Cervical Neoplasia [Phase 2]

Phase 2 clinical trial update on aminolevulinic acid photodynamic therapy for cervical persistent high-risk HPV infection and cervical intra…

CLINICAL_TRIALS trial_result · 2019-06-10

Clinical Trial Update: A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study [Phase 3]

A Phase 3 follow-up extension study assessing persistence of immune response to GSK's HPV vaccine in healthy Chinese females who completed t…

CLINICAL_TRIALS trial_result · 2018-11-20

Clinical Trial Update: An Innovative Treatment for Cervical Pre Cancer [NA]

Clinical trial update reporting completed results for an innovative treatment targeting cervical intraepithelial neoplasia.

CLINICAL_TRIALS trial_result · 2018-11-20

Clinical Trial Update: Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS) [Phase 3]

A Phase 3 randomized trial update on clinical management of ASCUS and LSIL (ALTS) related to Cervical Intraepithelial Neoplasia has complete…

CLINICAL_TRIALS trial_result · 2018-11-19

Clinical Trial Update: A Efficacy and Safety Study of Composite Gel Containing Black Raspberry Extract in Removing HPV From Patients With Cervical Intraepithelial Neoplasia(CIN) After Cervical Conization [Phase 2]

A Phase 2 clinical trial evaluating a composite gel containing black raspberry extract for efficacy and safety in removing HPV from patients…

CLINICAL_TRIALS trial_result · 2018-10-25

Clinical Trial Update: Eflornithine To Prevent Cervical Cancer in Patients With Cervical Intraepithelial Neoplasia [Phase 2]

Phase 2 trial update on using eflornithine to prevent cervical cancer in patients with cervical intraepithelial neoplasia (precancerous cond…

CLINICAL_TRIALS trial_result · 2018-09-07

Clinical Trial Update: A Study of VGX-3100 DNA Vaccine With Electroporation in Patients With Cervical Intraepithelial Neoplasia Grade 2/3 or 3 [Phase 2]

Phase 2 study of VGX-3100 DNA vaccine with electroporation in cervical intraepithelial neoplasia 2/3 or 3 has completed.

CLINICAL_TRIALS trial_result · 2018-08-16

Clinical Trial Update: A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls [Phase 3]

Phase 3 bridging trial update for a recombinant HPV 16/18 bivalent vaccine in preadolescent girls; status completed.

CLINICAL_TRIALS trial_result · 2018-08-15

Clinical Trial Update: Imiquimod Treatment of CIN Lesions [Phase 3]

Phase 3 clinical trial update for imiquimod in treating cervical intraepithelial neoplasia has been terminated.

CLINICAL_TRIALS trial_result · 2018-07-20

Clinical Trial Update: Vaccine Therapy in Preventing Cervical Cancer in Patients With Cervical Intraepithelial Neoplasia [Phase 1, Phase 2]

This entry reports results from a Phase 1/2 vaccine therapy trial designed to prevent progression to cervical cancer in women with cervical …

CLINICAL_TRIALS trial_result · 2018-07-09

Clinical Trial Update: Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3) [Phase 1]

Phase 1 study evaluating a therapeutic vaccine targeting HPV16 in patients with cervical intraepithelial neoplasia (CIN) 2/3; results have b…

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