Central Nervous System Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-02-21Clinical Trial Update: Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating dendritic cell–based immunotherapy for advanced solid tumors in children and young adults has completed …
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CLINICAL_TRIALS trial_result · 2018-09-18Clinical Trial Update: Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma [Phase 2]
Phase 2 trial evaluating temozolomide in newly diagnosed anaplastic oligodendroglioma or mixed oligoastrocytoma completed.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy [Phase 3]
Phase 3 trial evaluating sodium thiosulfate to prevent cisplatin-induced hearing loss in young patients with various pediatric cancers; stud…
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma [Phase 2]
Phase 2 trial evaluating observation or radiation therapy and/or chemotherapy and a second surgery in children after initial surgery for epe…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Radiation Therapy in Treating Young Patients With Gliomas [Phase 2]
Phase 2 trial update on radiation therapy for young patients with gliomas, completed with results posted in 2017.
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CLINICAL_TRIALS withdrawal · 2017-02-09Clinical Trial Update: OXC401-PO1s/WVU 1309 - A Pilot Study of Fosbretabulin With Bevacizumab in Recurrent High-Grade Gliomas [Phase 1]
A Phase 1 pilot trial of OXC401 (fosbretabulin) with bevacizumab for recurrent high-grade gliomas has been withdrawn. The study involves cen…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Safety and Efficacy of Cabazitaxel in Pediatric Patients With Refractory Solid Tumors Including Central Nervous System Tumors [Phase 1, Phase 2]
This trial update evaluates the safety and preliminary efficacy of cabazitaxel in pediatric patients with refractory solid tumors, including…
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CLINICAL_TRIALS research · 2016-06-13Clinical Trial Update: Proton Radiotherapy for Primary Central Nervous System Tumours in Adults [Phase 2]
A Phase 2 clinical trial conducted by Uppsala University is evaluating proton radiotherapy for primary central nervous system tumours in adu…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin [Phase 1, Phase 2]
Phase 1/2 trial evaluating paclitaxel, ifosfamide, and carboplatin followed by autologous stem cell transplant in patients with cisplatin-re…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas [Phase 3]
A Phase 3 trial comparing high-dose chemotherapy plus autologous stem cell transplantation to intermediate-dose chemotherapy plus autologous…
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CLINICAL_TRIALS trial_result · 2014-09-25Clinical Trial Update: Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma [Phase 2]
Clinical trial update reports results from a Phase 2 study of thalidomide plus temozolomide in relapsed or progressive pediatric central ner…
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CLINICAL_TRIALS trial_result · 2014-09-09Clinical Trial Update: Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer [Phase 2]
Phase 2 trial evaluating a five-drug combination (etoposide, cyclophosphamide, thalidomide, celecoxib, and fenofibrate) in relapsed or progr…
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Vinorelbine in Treating Children With Recurrent or Refractory Cancers [Phase 2]
Phase 2 clinical trial of vinorelbine in children with recurrent or refractory cancers completed; the study evaluated vinorelbine in pediatr…
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CLINICAL_TRIALS trial_result · 2014-02-13Clinical Trial Update: Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma [Phase 1]
A Phase 1 trial evaluating the combination of temozolomide and lomustine followed by radiation therapy for high-grade malignant glioma has c…
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CLINICAL_TRIALS trial_result · 2014-01-30Clinical Trial Update: Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma [Phase 1]
A Phase 1 trial evaluating imetelstat in pediatric patients with refractory or recurrent solid tumors or lymphoma has completed. The update …
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CLINICAL_TRIALS research · 2014-01-30Clinical Trial Update: The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study investigating the safety and feasibility of using 5-aminolevulinic acid (ALA) as an i…
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor [Phase 3]
A Phase 3 trial comparing radiation therapy to chemotherapy plus radiation therapy in newly diagnosed primary CNS germ cell tumors; results …
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CLINICAL_TRIALS trial_result · 2013-08-23Clinical Trial Update: Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors [Phase 2]
Phase 2 trial evaluating carboplatin and vincristine with radiation therapy, followed by adjuvant chemotherapy, in young patients with newly…
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CLINICAL_TRIALS trial_result · 2013-08-12Clinical Trial Update: High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy [Phase 2]
A Phase 2 clinical trial is evaluating high-dose chemotherapy with stem cell transplantation for metastatic germ cell tumors that did not re…
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors [Phase 2]
A Phase 2 trial of ixabepilone in patients with advanced cisplatin-refractory germ cell tumors has completed, evaluating outcomes across cen…
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Procarbazine in Treating Patients With Recurrent Brain Tumor [Phase 1, Phase 2]
Clinical trial update on procarbazine for recurrent brain tumors (Phase 1/Phase 2). The study status is completed.
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: COL-3 in Treating Patients With Progressive or Recurrent Brain Tumors [Phase 1, Phase 2]
Clinical trial update reporting completion of a Phase 1/2 study of COL-3 in patients with progressive or recurrent brain tumors.
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CLINICAL_TRIALS withdrawal · 2013-04-19Clinical Trial Update: Studying Cerebrospinal Fluid Proteins and Angiogenesis Proteins in Young Patients With Newly Diagnosed Central Nervous System Tumors
A pediatric clinical trial investigating cerebrospinal fluid and angiogenesis proteins in newly diagnosed brain and central nervous system t…
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CLINICAL_TRIALS trial_result · 2012-08-20Clinical Trial Update: A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects [Phase 2]
Phase 2 trial update on image-guided radiation therapy for pediatric brain tumors, with posted results.
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CLINICAL_TRIALS trial_result · 2012-07-02Clinical Trial Update: Radiation Therapy in Treating Patients With Brain Cancer [Phase 3]
A Phase 3 clinical trial evaluating radiation therapy for brain cancer has completed.