Cardiogenic Shock
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Sign up freeTop drugs studied for this disease
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FDA approval · 2024-03-06FDA Approved: DOBUTAMINE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for the dobutamine product from Hikma Pharmaceuticals USA Inc.
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock. [Phase 3]
Phase 3 trial evaluating low-dose hydrocortisone and fludrocortisone in adult cardiogenic shock has completed.
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FDA approval · 2023-09-08FDA Approved: DOBUTAMINE HYDROCHLORIDE IN DEXTROSE — Supplemental Application (Baxter Healthcare Corporation)
FDA approved a supplemental application for DOBUTAMINE HYDROCHLORIDE IN DEXTROSE (Baxter).
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: Cardiogenic Shock Intravascular Cooling Trial [NA]
Completed clinical trial on intravascular cooling for cardiogenic shock; results posted in 2023.
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FDA approval · 2022-12-21FDA Approved: DOBUTAMINE — Original Application (Slate Run Pharmaceuticals)
FDA approves Slate Run Pharmaceuticals' dobutamine—Original Application (ANDA 216131)—granting approval of a generic dobutamine product. Thi…
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CLINICAL_TRIALS trial_result · 2022-10-26Clinical Trial Update: Ivabradine Effects in Cardiogenic Shock Requiring Inotropic Support [Phase 3]
Phase 3 trial update on ivabradine for cardiogenic shock requiring inotropic support in heart failure patients.
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CLINICAL_TRIALS trial_result · 2022-09-16Clinical Trial Update: Synchronized Cardiac Assist for Cardiogenic Shock
A completed clinical trial evaluating synchronized cardiac assist for patients with cardiogenic shock, with results posted in 2022.
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FDA approval · 2022-09-15FDA Approved: NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE — Original Application (WG Critical Care, LLC)
FDA approves norepinephrine bitartrate in sodium chloride for injection under an original application by WG Critical Care, LLC, a vasopresso…
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CLINICAL_TRIALS trial_result · 2021-10-08Clinical Trial Update: Adrecizumab in Cardiogenic Shock [Phase 2, Phase 3]
Clinical trial update for Adrecizumab in cardiogenic shock, spanning Phase 2 and Phase 3, with completed status.
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CLINICAL_TRIALS trial_result · 2021-07-26Clinical Trial Update: Study of Multistep Pharmacological and Invasive Management for Cardiogenic Shock [Phase 2]
A Phase 2 clinical trial investigating multistep pharmacological and invasive management for cardiogenic shock has completed.
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CLINICAL_TRIALS trial_result · 2021-06-29Clinical Trial Update: Early Insertion of Axillary Impella® With VA ECMO [NA]
Clinical trial update for early insertion of Axillary Impella with VA ECMO in cardiogenic shock; study terminated with results posted in 202…
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CLINICAL_TRIALS withdrawal · 2020-10-05Clinical Trial Update: Comparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac Output [Phase 4]
A Phase 4 trial comparing ARNI to other oral vasodilator therapies in patients with cardiogenic shock was withdrawn.
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: Milrinone Versus Dobutamine in Critically Ill Patients [Phase 4]
Phase 4 trial comparing milrinone to dobutamine in critically ill patients with low cardiac output syndrome or cardiogenic shock has complet…
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CLINICAL_TRIALS trial_result · 2019-10-14Clinical Trial Update: Clinical Study of Extra-Corporal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction [Phase 4]
A Phase 4 clinical trial evaluating extracorporeal life support in patients with cardiogenic shock complicating acute myocardial infarction …
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FDA approval · 2019-05-24FDA Approved: DOBUTAMINE IN DEXTROSE — Supplemental Application (Hospira, Inc.)
FDA approved a supplemental application for Dobutamine in Dextrose from Hospira, Inc.
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CLINICAL_TRIALS trial_result · 2019-05-23Clinical Trial Update: Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine [Phase 4]
Phase 4 clinical trial update assessing the effect of ivabradine in patients with Stage D heart failure and cardiogenic shock on dobutamine.
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CLINICAL_TRIALS research · 2019-02-22Clinical Trial Update: Central Venous Pressure (CVP) Changes do Not Predict Preload Unresponsiveness
The clinical trial update reports that central venous pressure (CVP) changes do not reliably predict preload unresponsiveness in patients wi…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock [Phase 4]
A Phase 4 trial comparing epinephrine and norepinephrine for efficacy and tolerability in cardiogenic shock has completed.
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CLINICAL_TRIALS research · 2019-01-23Clinical Trial Update: The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock Patients [NA]
This clinical trial examines whether simultaneous renal replacement therapy affects outcomes for patients receiving extracorporeal membrane …
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CLINICAL_TRIALS research · 2018-07-17Clinical Trial Update: Veno-arterial Extracorporeal Membrane Oxygenation Prior to Left Ventricular Assist Device Implantation.
A clinical trial update on using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) before left ventricular assist device (LVAD) im…
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction [NA]
This completed clinical trial from the University of Leipzig evaluated mild hypothermia in patients with cardiogenic shock complicating acut…
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CLINICAL_TRIALS research · 2018-04-11Clinical Trial Update: Hemodynamic Assessment in Cardiogenic Shock Regarding the Etiology
This clinical trial update discusses a study evaluating hemodynamic assessment to determine the etiology of cardiogenic shock.
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: Levosimendan Efficacy for Veno-arterial ECMO Weaning: a Retrospective Study
A retrospective study evaluating whether levosimendan facilitates weaning from veno-arterial ECMO in patients with cardiogenic shock.
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: Efficacy and Safety on Heart Rate Control With Ivabradine on Cardiogenic Shock [Phase 4]
Phase 4 trial update evaluating efficacy and safety of ivabradine for heart rate control in patients with cardiogenic shock.
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: Norepinephrine vs Norepinephrine and Dobutamine in Cardiogenic Shock [Phase 3]
A Phase 3 trial update comparing norepinephrine alone versus norepinephrine plus dobutamine in cardiogenic shock; current status is unknown.