Cardiogenic Shock
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage C [Phase 1, Phase 2]
The document is a clinical trial update for an early-stage safety and efficacy study of istaroxime in cardiogenic shock (Phase 1/Phase 2) co…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Effect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic Shock [Phase 3]
Phase 3 clinical trial evaluating early use of levosimendan on top of conventional inotrope therapy to improve a combined morbidity-mortalit…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
A clinical trial evaluating the left ventricular physiological effects of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) suppor…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Inhaled Isoflurane for Sedation of Invasively Ventilated Patients With Cardiogenic Shock on Extracorporeal Membrane Oxygenation [Phase 3]
A Phase 3 clinical trial is evaluating inhaled isoflurane for sedation of invasively ventilated patients with cardiogenic shock on ECMO; the…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Prospective Validation of the STOPSHOCK Score - Artificial Intelligence Based Predictive Scoring System to Identify the Risk of Developing Cardiogenic Shock (CS) in Patients Suffering From Acute Coronary Syndrome (ACS)
This clinical trial update describes prospective validation of STOPSHOCK, an AI-based predictive scoring system to identify the risk of deve…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Digital Out-of-hospital Management on Clinical Outcomes in Patients With Early Cardiogenic Shock [NA]
Clinical trial update on a digital out-of-hospital management strategy for patients with early cardiogenic shock; the study is currently rec…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Low-Dose Dobutamine and Single-Dose Tocilizumab in Acute Myocardial Infarction With High Risk of Cardiogenic Shock [Phase 2]
Phase 2 trial evaluating low-dose dobutamine and a single-dose tocilizumab in patients with acute myocardial infarction at high risk of card…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: The Role of Swan-Ganz Catheter in Hemodynamic Resuscitation for Patients With Cardiogenic Shock [NA]
A clinical trial at Bach Mai Hospital is evaluating the role of Swan-Ganz catheters in hemodynamic resuscitation for patients with cardiogen…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Cardiac Power Output in Cardiogenic Shock Patients [EARLY_Phase 1]
This clinical trial update describes an early-phase 1 study evaluating cardiac power output in patients with heart failure and cardiogenic s…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: National Cardiogenic Shock Initiative
The National Cardiogenic Shock Initiative trial (NCT03677180) has completed and posted results. The study evaluated management strategies fo…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Pilot Italian Cardiogenic Shock Initiative
The clinical trial update notes that Fondazione GISE Onlus's Pilot Italian Cardiogenic Shock Initiative is currently recruiting participants…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Pharmacokinetic Modelling of Levosimendan in Adults
This clinical trial update concerns pharmacokinetic modelling of Levosimendan in adults. The study is currently not yet recruiting and targe…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function. [Phase 3]
A Phase 3 trial evaluating early initiation of empagliflozin in cardiogenic shock and its effects on mortality, rehospitalization, left vent…
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CLINICAL_TRIALS other · 2025-06-24Clinical Trial Update: Recurrent Ventricular Arrythmias in ICU
A clinical trial in France is investigating recurrent ventricular arrhythmias in ICU patients; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock [NA]
Ongoing clinical trial evaluating transcatheter mitral valve repair for patients with inotrope-dependent cardiogenic shock, with recruitment…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Cardiogenic Shock Working Group Registry
Clinical trial registry entry for the Cardiogenic Shock Working Group Registry sponsored by Tufts Medical Center; the study is currently rec…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Efferon CT Hemoadsorption for Cardiogenic Shock in Acute Myocardial Infarction [NA]
A clinical trial evaluating Efferon CT hemoadsorption for cardiogenic shock in patients with acute myocardial infarction is currently recrui…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Early Beta Blocker Administration in STEMI Patients With SCAI B Status [NA]
A clinical trial evaluating early beta-blocker administration in ST-segment Elevation Myocardial Infarction patients with SCAI B status is c…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: SURPASS Impella 5.5 Study
Clinical trial update for the SURPASS Impella 5.5 study sponsored by Abiomed; the study addresses cardiogenic shock and acute decompensated …
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Augmented Pacing for Shock in the Cardiac Intensive Care Unit [NA]
A Vanderbilt University Medical Center trial is evaluating augmented pacing to treat shock in patients with cardiogenic shock and bradycardi…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Effect of Mild Therapeutic Hypothermia on the Doses of Vasopressors and Inotropes in Cardiogenic Shock Complicating Acute Myocardial Infarction [NA]
A completed clinical trial evaluated whether mild therapeutic hypothermia affects the doses of vasopressors and inotropes used in cardiogeni…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure
An ongoing clinical trial at Tufts Medical Center is examining changes in skeletal muscle thickness in patients with acute heart failure. Th…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Optimal ECMO Flow in the Critical Phase of Cardiogenic Shock to Optimize Peripheral Organ Perfusion and Myocardial Stress
This clinical trial aims to determine the optimal ECMO flow during the critical phase of cardiogenic shock to improve peripheral organ perfu…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Ciprofol's Impact on Oxygenator Function in Extracorporeal Membrane Oxygenation (ECMO) Patients [Phase 4]
Phase 4 clinical trial evaluating Ciprofol's impact on oxygenator function in ECMO patients with ARDS and related cardiopulmonary conditions…
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: Effect of Peripheral VA-ECMO Flow Variations on the Pulmonary Arterial Occlusion Pressure (PAPO) in Patients With Refractory Cardiogenic Shock. [NA]
A completed clinical trial from Assistance Publique - Hôpitaux de Paris evaluated how variations in peripheral VA-ECMO flow affect the pulmo…