Cardiac Allograft Vasculopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-18Clinical Trial Results: Cardiac Allograft Vasculopathy Inhibition With Alirocumab [Phase 2]
Phase 2 trial evaluating alirocumab for inhibition of cardiac allograft vasculopathy; results completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Cardiac Allograft Vasculopathy Inhibition With Alirocumab [Phase 2]
Phase 2 trial update evaluating alirocumab for inhibition of cardiac allograft vasculopathy has completed.
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CLINICAL_TRIALS withdrawal · 2025-11-06Clinical Trial Update: Determining the Association of Microvascular Disease as Assessed by PET and Graft Injury by Donor Derived Cell Free DNA
A clinical trial investigating the association between microvascular disease by PET and graft injury via donor-derived cell-free DNA has bee…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Comparing PCCT With ICA and IVUS in Detecting Cardiac Allograft Vasculopathy
This clinical trial compares photon-counting computed tomography (PCCT) with invasive coronary angiography (ICA) and intravascular ultrasoun…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Early Post Transplant Cardiac Allograft Vasculopathy
Ongoing clinical trial update from the Ottawa Heart Institute researching early post-transplant cardiac allograft vasculopathy; the study is…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: AERIAL Trial: Antiplatelet Therapy in Heart Transplantation [Phase 3]
Clinical trial update for the AERIAL Phase 3 study evaluating antiplatelet therapy in heart transplant recipients with cardiac allograft vas…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation [NA]
This ClinicalTrials.gov entry reports the MARINER trial evaluating multiparametric cardiac PET to surveil cardiac allograft vasculopathy in …
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Unraveling Mechanism of Action of Extracorporeal Photopheresis in Heart and Lung Transplant Patients
This completed clinical trial examines the mechanism of action of extracorporeal photopheresis in heart and lung transplant recipients. It a…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Physiologic Assessment of Microvascular Function in Heart Transplant Patients
This clinical trial is evaluating physiologic assessment of microvascular function in heart transplant patients. It is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Advanced Cardiac Imaging in Cardiac Allograft Vasculopathy
A clinical trial evaluating advanced cardiac imaging for cardiac allograft vasculopathy in heart transplant recipients has been terminated.
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Extracorporeal Photopheresis and Early Cardiac Graft Vasculopathy [NA]
A completed clinical trial evaluating extracorporeal photopheresis for cardiac allograft vasculopathy and heart transplant rejection.
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: Microvascular Cardiac Allograft Vasculopathy Trial
A clinical trial update shows that a study evaluating microvascular cardiac allograft vasculopathy is currently recruiting, sponsored by the…
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: Impact of Evolocumab in Cardiac Transplant Patients With CAV [Phase 2]
A Phase 2 trial evaluating evolocumab in heart transplant recipients with cardiac allograft vasculopathy has posted results.
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: Impact of SGLT2 Inhibitors in Heart Transplant Recipients [Phase 2]
Phase 2 trial assessing the impact of SGLT2 inhibitors in heart transplant recipients, investigating effects on heart failure, cardiac allog…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Endothelin-1 and Cardiac Allograft Vasculopathy (CAV) [Phase 4]
Phase 4 clinical trial update on Endothelin-1 for Cardiac Allograft Vasculopathy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Cholesterol Lowering With EVOLocumab to Prevent Cardiac Allograft Vasculopathy in De-novo Heart Transplant Recipients [Phase 3]
Phase 3 trial evaluating evolocumab to prevent cardiac allograft vasculopathy in de novo heart transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients [Phase 4]
Phase 4 trial update investigating efficacy and safety of alirocumab to prevent early cardiac allograft vasculopathy in recent heart transpl…
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CLINICAL_TRIALS trial_result · 2021-09-30Clinical Trial Update: Safety and Efficacy of Everolimus - Eluting Bioresorbable Vascular Scaffold for Cardiac Allograft Vasculopathy [Phase 4]
Phase 4 trial update on safety and efficacy of everolimus-eluting bioresorbable vascular scaffold for cardiac allograft vasculopathy has bee…
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CLINICAL_TRIALS trial_result · 2021-05-03Clinical Trial Update: The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation [Phase 3]
Phase 3 trial evaluating de-novo use of eculizumab in presensitized cardiac transplant patients completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: Real Time Myocardial Perfusion Echocardiography for Coronary Allograft Vasculopathy [Phase 4]
Phase 4 clinical trial evaluating real-time myocardial perfusion echocardiography for monitoring cardiac allograft vasculopathy has complete…
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CLINICAL_TRIALS withdrawal · 2019-03-14Clinical Trial Update: A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of Heart Transplant Recipients Called Cardiac Allograft Vasculopathy (CAV) [Phase 3]
Phase 3 trial evaluating Thymoglobulin® to prevent cardiac allograft vasculopathy in heart transplant recipients was withdrawn.
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Effect of Ivabradine on Exercise Capacity After Heart Transplantation [Phase 4]
Phase 4 clinical trial evaluating the effect of ivabradine on exercise capacity after heart transplantation.
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CLINICAL_TRIALS research · 2019-01-17Clinical Trial Update: Heart Failure After Heart Transplantation Due to Chronic Rejection [NA]
Clinical trial update on heart failure after heart transplantation due to chronic rejection, with current status listed as unknown.
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CLINICAL_TRIALS research · 2018-07-10Clinical Trial Update: Cardiac Allograft Vasculopathy and Dobutamine Stress Echocardiography / Brain Natriuretic Peptide Coupling [NA]
Completed clinical trial evaluating cardiac allograft vasculopathy using dobutamine stress echocardiography and brain natriuretic peptide co…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Optical Coherence Tomography (OCT) to Evaluate Cardiac Allograft Vasculopathy (CAV) in Patient's Post Heart Transplant
A completed clinical trial used Optical Coherence Tomography to evaluate cardiac allograft vasculopathy in patients after heart transplantat…