Bronchopulmonary Dysplasia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Surfactant Positive Airway Pressure and Pulse Oximetry Trial [Phase 3]
Phase 3 clinical trial update for surfactant positive airway pressure with pulse oximetry in newborns; completed with results posted in 2014…
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CLINICAL_TRIALS trial_result · 2014-11-10Clinical Trial Update: Continuous Positive Airway Pressure Via Binasal Prong vs Nasal Mask: a Randomised Controlled Trial [NA]
A completed randomized trial comparing continuous positive airway pressure delivered via binaasal prong versus nasal mask in infants at risk…
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: Safety and Efficacy Evaluation of PNEUMOSTEM® Treatment in Premature Infants With Bronchopulmonary Dysplasia [Phase 1]
Phase 1 clinical trial evaluating the safety and efficacy of PNEUMOSTEM in premature infants with bronchopulmonary dysplasia has been comple…
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CLINICAL_TRIALS research · 2014-01-31Clinical Trial Update: Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonates [Phase 1]
Phase 1 clinical trial evaluating autologous cord blood infusion to prevent and treat complications in preterm neonates, sponsored by Pomera…
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS
The trial evaluated initiating nasal continuous positive airway pressure before surfactant treatment in very preterm infants with respirator…
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CLINICAL_TRIALS trial_result · 2013-08-30Clinical Trial Update: Randomized Trial of Hydrocortisone in Very Preterm High-Risk Infants [Phase 2]
A randomized Phase 2 trial evaluating hydrocortisone in very preterm high-risk infants has completed, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-03-12Clinical Trial Update: Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator [NA]
A completed clinical trial evaluated nasal ventilation in preterm infants to decrease the time on mechanical ventilatory support for broncho…
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CLINICAL_TRIALS trial_result · 2013-01-28Clinical Trial Update: Inhaled Nitric Oxide to Prevent and Treat Bronchopulmonary Dysplasia [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial evaluating inhaled nitric oxide for prevention and treatment of bronchopulmonary dysplasia has completed.
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Study of Motavizumab (MEDI-524) and Palivizumab Administered Sequentially in the Same Respiratory Syncytial Virus (RSV) Season [Phase 2]
A Phase 2 trial evaluated sequential administration of motavizumab and palivizumab during an RSV season in infants at risk for RSV infection…
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CLINICAL_TRIALS trial_result · 2012-08-02Clinical Trial Update: Montelukast in Very Low Birthweight Infants [Phase 1]
This clinical trial update reports completed Phase 1 results for using montelukast in very low birthweight infants with bronchopulmonary dys…
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CLINICAL_TRIALS trial_result · 2012-07-27Clinical Trial Update: Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis [Phase 3]
A Phase 3 trial evaluating clarithromycin prophylaxis in preterm infants colonized with Ureaplasma urealyticum and Mycoplasma hominis to pre…
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants. [Phase 2]
Phase 2 trial of SURFAXIN (lucinactant) for the prevention of bronchopulmonary dysplasia in very low birth weight infants was terminated; re…
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CLINICAL_TRIALS trial_result · 2012-03-30Clinical Trial Update: Assessment of the Pulmonary Diffusion Capacity in Healthy Infants and Infants With Chronic Lung Disease
This clinical trial evaluated pulmonary diffusion capacity in healthy infants and infants with chronic lung disease, such as bronchopulmonar…
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CLINICAL_TRIALS withdrawal · 2011-12-30Clinical Trial Update: Phase 1 Intravenous Citrulline for the Prevention of Bronchopulmonary Dysplasia in Preterm Infants [Phase 1]
A Phase 1 clinical trial of intravenous citrulline to prevent bronchopulmonary dysplasia in preterm infants has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-11-17Clinical Trial Update: Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS) [Phase 1, Phase 2]
This clinical trial update reports safety, pharmacokinetics, and anti-inflammatory effects of CC10 protein in premature infants with respira…
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CLINICAL_TRIALS trial_result · 2011-07-19Clinical Trial Update: Palivizumab for Prevention of Severe Respiratory Syncytial Virus Infection in Russian Children [Phase 2, Phase 3]
Phase 2/3 clinical trial update on palivizumab for prevention of severe respiratory syncytial virus infection in high-risk Russian infants, …
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CLINICAL_TRIALS trial_result · 2011-06-28Clinical Trial Update: NCPAP + Heliox as a Treatment for Infant Respiratory Distress Syndrome (RDS) [Phase 2]
A Phase 2 trial evaluating NCPAP plus heliox for infant respiratory distress syndrome has completed. The study also considers bronchopulmona…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity [Phase 3]
Phase 3 clinical trial evaluating probiotics to prevent preterm birth and related neonatal morbidity was terminated.
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CLINICAL_TRIALS trial_result · 2011-04-06Clinical Trial Update: Surfactant Administration During Spontaneous Breathing [Phase 4]
A Phase 4 trial update examining surfactant administration during spontaneous breathing; current status is unknown.
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FDA approval · 2011-04-04FDA Approved: SYNAGIS — Supplemental Application (Swedish Orphan Biovitrum AB (publ))
The FDA approved a supplemental application for Synagis (palivizumab) filed by Swedish Orphan Biovitrum AB (publ).
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CLINICAL_TRIALS trial_result · 2011-03-31Clinical Trial Update: Efficacy of Clarithromycin Treatment in Prevention of Chronic Lung Disease in Premature Infants [Phase 4]
Phase 4 clinical trial evaluating the efficacy of clarithromycin to prevent bronchopulmonary dysplasia in premature infants. The study has c…
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CLINICAL_TRIALS trial_result · 2010-12-29Clinical Trial Update: Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants. [Phase 2]
A Phase 2 pilot trial evaluating whether a topical steroid can prevent bronchopulmonary dysplasia in extremely premature infants. The curren…
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CLINICAL_TRIALS trial_result · 2010-09-23Clinical Trial Update: Intratracheal Umbilical Cord-derived Mesenchymal Stem Cells for Severe Bronchopulmonary Dysplasia [Phase 1]
Phase 1 clinical trial update investigating intratracheal administration of umbilical cord-derived mesenchymal stem cells for severe broncho…
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CLINICAL_TRIALS trial_result · 2010-06-24Clinical Trial Update: Neonatal Intensive Care (NICU) Course and Hospital Outcome of Infants With BPD Treated Using Inhaled Nitric Oxide
This completed clinical trial evaluated the NICU course and hospital outcomes of infants with bronchopulmonary dysplasia treated with inhale…
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CLINICAL_TRIALS trial_result · 2010-02-26Clinical Trial Update: Cysteine Supplementation in Critically Ill Neonates [Phase 2, Phase 3]
Clinical trial update for cysteine supplementation in critically ill neonates spanning Phase 2 and Phase 3, with multiple neonatal condition…