Breast Cancer
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CLINICAL_TRIALS trial_result · 2013-10-24Clinical Trial Update: A Phase I/II Study of ABI-007 (Abraxane®, Nab®-Paclitaxel)and Vinorelbine in Patients With Stage IV (Metastatic) Breast Cancer [Phase 1, Phase 2]
Phase I/II study of Abraxane (nab-paclitaxel) with vinorelbine in metastatic breast cancer was terminated with results posted in 2013.
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CLINICAL_TRIALS research · 2013-10-24Clinical Trial Update: Assessing Women's Attitudes About the Risk of Infertility Related to Adjuvant Therapy for Early Breast Cancer [NA]
The update summarizes a study examining women's attitudes toward the potential risk of infertility from adjuvant therapy for early breast ca…
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CLINICAL_TRIALS trial_result · 2013-10-24Clinical Trial Update: Biomarker (p53 Gene) Analysis and Combination Chemotherapy Followed by Radiation Therapy and Surgery in Treating Women With Large Operable or Locally Advanced or Inflammatory Breast Cancer [Phase 3]
Phase 3 trial assessing p53 biomarker analysis and sequence of combination chemotherapy followed by radiation therapy and surgery for women …
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CLINICAL_TRIALS trial_result · 2013-10-23Clinical Trial Update: Faith Moves Mountains: A Community Based Participatory Research (CBPR) Appalachian Wellness & Cancer Prevention Program [NA]
A community-based participatory research cancer prevention program in Appalachia focused on wellness and cancer prevention across multiple c…
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CLINICAL_TRIALS withdrawal · 2013-10-22Clinical Trial Update: A Randomized, Open-label Phase III Trial of Mapisal® Versus an Urea Hand-foot Cream as Prophylaxis for Capecitabine-induced Hand-foot Syndrome in Patients With Gastrointestinal Tumors or Breast Cancer
A Phase III randomized trial comparing Mapisal to a urea hand-foot cream for preventing capecitabine-related hand-foot syndrome in patients …
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CLINICAL_TRIALS trial_result · 2013-10-22Clinical Trial Update: Computer-Based Comprehensive Geriatric Assessment in Oncology for Individuals 70 or Older With Gastrointestinal Malignancies
A completed clinical trial update on a computer-based comprehensive geriatric assessment in oncology for individuals 70 and older, involving…
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FDA approval · 2013-10-18FDA Approved: TYKERB — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for Tykerb (lapatinib) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2013-10-18Clinical Trial Update: BIBW 2992 (Afatinib) and Vinorelbine [Phase 2]
Phase 2 trial of afatinib (BIBW 2992) in combination with vinorelbine for stage IV breast cancer was terminated.
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CLINICAL_TRIALS trial_result · 2013-10-17Clinical Trial Update: 6 Weeks Treatment of Locally Advanced Breast Cancer With BIBW 2992 (Afatinib) or Lapatinib or Trastuzumab [Phase 2]
A Phase 2 study comparing afatinib, lapatinib, and trastuzumab in locally advanced breast cancer has completed, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-10-17Clinical Trial Update: Phase I Open Label Trial to Assess Safety of BIBW 2992 (Afatinib) in Combination With Herceptin® in Patients With HER2-positive Advanced Breast Cancer. [Phase 1]
Phase I open-label study assessing the safety of combining afatinib with trastuzumab in patients with HER2-positive advanced breast cancer; …
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis [Phase 2]
A Phase 2 trial evaluating bevacizumab with etoposide and cisplatin in breast cancer patients with brain and/or leptomeningeal metastases ha…
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CLINICAL_TRIALS research · 2013-10-16Clinical Trial Update: 18F-FLT Positron Emission Tomography and Magnetic Resonance Imaging of the Breast [Phase 4]
A Phase 4 clinical trial update evaluating 18F-FLT PET and MRI for breast cancer, sponsored by National Taiwan University Hospital, with the…
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CLINICAL_TRIALS research · 2013-10-16Clinical Trial Update: A Continuing Cancer Service Model Emphasizing on Functional Restoration: Model for Breast Cancer [NA]
A clinical trial update from National Taiwan University Hospital describes a cancer service model focused on functional restoration for brea…
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Stereotactic Directional Vacuum-Assisted Breast Biopsy
This clinical trial update reports the completion of a study evaluating stereotactic directional vacuum-assisted breast biopsy for diagnosin…
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CLINICAL_TRIALS trial_result · 2013-10-15Clinical Trial Update: Use of Trastuzumab to Induce Increased ER Expression in ER-negative/Low, Her-2/Neu Positive Breast Cancer [Phase 1, Phase 2]
A Phase 1/2 study tested whether trastuzumab can increase estrogen receptor expression in ER-negative/low, HER2-positive breast cancer; the …
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: An Open Label Phase II Trial of BIBW 2992 in Patients With HER2-negative Metastatic Breast Cancer [Phase 2]
Open-label Phase II trial of BIBW 2992 (afatinib) in HER2-negative metastatic breast cancer completed; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Bevacizumab With or Without Cyclophosphamide and Methotrexate: A Pilot Study in Women With Operable Breast Cancer [NA]
Pilot trial evaluating bevacizumab with or without cyclophosphamide and methotrexate in women with operable breast cancer; the study is comp…
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CLINICAL_TRIALS trial_result · 2013-10-11Clinical Trial Update: Use of Dermal Matrix in Breast Reconstruction [NA]
A terminated clinical trial evaluating the use of a dermal matrix in breast reconstruction for breast cancer patients, with results posted i…
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CLINICAL_TRIALS trial_result · 2013-10-11Clinical Trial Update: Pain Management Following TRAM Flap for Breast Reconstruction [NA]
A completed clinical trial evaluating pain management after TRAM flap breast reconstruction.
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CLINICAL_TRIALS trial_result · 2013-10-10Clinical Trial Update: Phase II Trial of Oxaliplatin in Combination With S-1(SOX) in Patients With Recurrent or Metastatic Breast Cancer [Phase 2]
Completed Phase II clinical trial evaluating oxaliplatin in combination with S-1 (SOX) for recurrent or metastatic breast cancer.
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CLINICAL_TRIALS trial_result · 2013-10-09Clinical Trial Update: Magnetic Resonance Imaging in Women Receiving Chemotherapy for Stage III Breast Cancer [Phase 2]
A Phase 2 trial evaluating magnetic resonance imaging in women undergoing chemotherapy for stage III breast cancer has completed enrollment,…
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CLINICAL_TRIALS trial_result · 2013-10-09Clinical Trial Update: Epothilone B in Treating Patients With CNS Metastases From Breast Cancer [Phase 2]
Phase 2 trial of Epothilone B in patients with CNS metastases from breast cancer has completed and results have been posted.
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FDA approval · 2013-10-08FDA Approved: FASLODEX — Supplemental Application (AstraZeneca Pharmaceuticals LP)
The FDA approved a supplemental application for FASLODEX (fulvestrant) submitted by AstraZeneca Pharmaceuticals LP.
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CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Trastuzumab and Interleukin-2 in Treating Patients With Metastatic Breast Cancer [Phase 2]
Phase 2 trial evaluating the combination of trastuzumab and interleukin-2 in metastatic breast cancer has completed.
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CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Effectiveness of Accelerated Intervention With Compression Sleeve in Mild and Moderate Breast Cancer-related Lymphedema [NA]
This document reports an update on a clinical trial examining whether accelerated intervention with a compression sleeve improves outcomes i…