Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2014-02-04Clinical Trial Update: Systemic Therapy With or Without Upfront Surgery in Metastatic Breast Cancer [Phase 3]
A Phase 3 trial evaluating systemic therapy with or without upfront surgery in metastatic breast cancer was terminated.
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CLINICAL_TRIALS research · 2014-02-04Clinical Trial Update: The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture
This clinical trial studying Claudin 3 biology in primary human mammary epithelial cells sponsored by Hackensack Meridian Health has been te…
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CLINICAL_TRIALS research · 2014-01-30Clinical Trial Update: Epidemiology and Management of Metastatic Breast Cancer
Clinical trial update sponsored by AstraZeneca discusses epidemiology and management of metastatic breast cancer; the study is reported as c…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy [Phase 3]
Phase 3 trial evaluating whether zoledronic acid added to letrozole can mitigate cancer treatment–related bone loss in postmenopausal women …
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CLINICAL_TRIALS withdrawal · 2014-01-28Clinical Trial Update: Vorinostat Before Surgery in Treating Patients With Triple-Negative Breast Cancer [NA]
The clinical trial evaluating vorinostat before surgery for Stage II/IIIA breast cancer, including triple-negative breast cancer, has been w…
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CLINICAL_TRIALS trial_result · 2014-01-27Clinical Trial Update: A Trial of Tivozanib (AV-951) in Combination With Capecitabine (Xeloda®) in Subjects With Advanced Solid Tumors [Phase 1]
A Phase 1 trial evaluating the safety of combining tivozanib with capecitabine in adults with advanced solid tumors, including locally advan…
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CLINICAL_TRIALS trial_result · 2014-01-27Clinical Trial Update: Fear of Recurrence Pilot Intervention for Women With Breast Cancer [Phase 1]
A completed Phase 1 trial evaluating a pilot intervention to address fear of recurrence in women with breast cancer.
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: Breast Cancer, Aromatase Inhibitor Therapy, and Sexual Functioning: The Effects of Vaginal Testosterone Therapy [EARLY_Phase 1]
An early-phase (Phase 1) trial evaluated vaginal testosterone therapy for sexual functioning in women with breast cancer on aromatase inhibi…
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Malignant Bone Disease. [Phase 2]
Phase 2 study evaluating loading doses of intravenous ibandronate (Bondronat) in patients with breast cancer and malignant bone disease; the…
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: Phase II Study of Simvastatin in Primary Breast Cancer; Test of Its Potential Selectivity on Basal Subtype Breast Cancer [Phase 2]
This document discusses a Phase II clinical trial investigating simvastatin in primary breast cancer, including evaluation of its potential …
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: Biomarkers of Fatigue Related to Adjuvant Chemotherapy for Breast Cancer
This document discusses biomarkers of fatigue related to adjuvant chemotherapy in breast cancer patients.
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: Comparative Genomic and Genetic Analysis of Paired Primary Breast - Metastatic Tumor Specimens Using High-throughput Platforms
A research study analyzing paired primary and metastatic breast cancer samples using high-throughput genomic platforms to compare their gene…
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: Analysis of Prognostic and Predictive Genomic Signatures Using Archival Paraffin-embedded Tumor Specimens in Breast Cancer
This document is an update on a clinical trial that analyzes prognostic and predictive genomic signatures in archival paraffin-embedded brea…
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: A Non-Interventional Study With Aromasin® As Adjuvant Treatment Of Invasive Early Breast Cancer
Non-interventional study evaluating Aromasin (exemestane) as adjuvant treatment for invasive early breast cancer; results have been posted f…
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: Analysis of Prognostic and Predictive Genomic Signatures Using Archival Paraffin-embedded Breast Tumor - a Pilot Study
A pilot study analyzing archival paraffin-embedded breast tumor samples to identify prognostic and predictive genomic signatures.
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EMA withdrawal · 2014-01-21EMA Lapsed: Docetaxel Teva Pharma (docetaxel) — Teva Pharma B.V.
The EMA lists Docetaxel Teva Pharma as lapsed (withdrawn) for multiple indications including non-small cell lung carcinoma, breast neoplasms…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Saracatinib in Treating Patients With Metastatic or Locally Advanced Breast Cancer That Cannot Be Removed By Surgery [Phase 2]
This is a Phase 2 trial update of saracatinib for metastatic or unresectable locally advanced breast cancer. It includes estrogen receptor-n…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer [Phase 1]
Phase 1 trial evaluating lapatinib in combination with radiation therapy for brain metastases from HER2-positive breast cancer. Results post…
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CLINICAL_TRIALS trial_result · 2014-01-16Clinical Trial Update: Ultrasound Targeting for the Lumpectomy Cavity
Completed clinical trial evaluating ultrasound targeting for the lumpectomy cavity in breast cancer; results summarize this imaging-guided a…
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CLINICAL_TRIALS trial_result · 2014-01-16Clinical Trial Update: Quality Study of Anesthetic Technique on Breast Cancer Surgery [Phase 4]
Phase 4 trial completed evaluating how a specific anesthetic technique impacts postoperative pain, quality of recovery, and patient satisfac…
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CLINICAL_TRIALS trial_result · 2014-01-16Clinical Trial Update: Sensory Morbidity Following Breast Surgery
A completed clinical trial update examining sensory morbidity after breast surgery, detailing postoperative sensory outcomes in individuals …
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FDA approval · 2014-01-15FDA Approved: FEMARA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for FEMARA (letrozole) from Novartis, indicating approval of a supplement to the original NDA.
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CLINICAL_TRIALS research · 2014-01-14Clinical Trial Update: Prevention of Breast Cancer Recurrence Through Weight Control, Diet, and Physical Activity Intervention [Phase 3]
Phase 3 clinical trial evaluating whether weight control, diet, and physical activity can reduce the recurrence of breast cancer.
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CLINICAL_TRIALS trial_result · 2014-01-14Clinical Trial Update: Lapatinib and Vinorelbine in Treating Women With HER2-Overexpressing Locally Advanced or Metastatic Breast Cancer [Phase 1]
Phase 1 trial evaluating the combination of lapatinib and vinorelbine in HER2-overexpressing locally advanced or metastatic breast cancer ha…
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CLINICAL_TRIALS research · 2014-01-14Clinical Trial Update: Development of Predictive Biomarkers and Novel Approached to Therapy in Breast Cancer
This clinical trial update describes ongoing research into predictive biomarkers and new treatment approaches for breast cancer.