Breast Cancer

• CLINICAL_TRIALS trial_result · 2015-05-12
  Clinical Trial Update: Adjuvant Chemotherapy in Treating Women Who Have Undergone Resection for Relapsed Breast Cancer; Chemotherapy as Adjuvant for LOcally Recurrent Breast Cancer [Phase 3]

  Phase 3 clinical trial evaluating adjuvant chemotherapy after surgical resection for relapsed or locally recurrent breast cancer; results we…

• CLINICAL_TRIALS trial_result · 2015-05-12
  Clinical Trial Update: Changes in Cancer-related Cytokines After Participation in a Physical Activity Behavior Change Intervention (CICK Study) [NA]

  Completed clinical trial examining how cancer-related cytokines change after a physical activity behavior-change program in breast cancer pa…

• CLINICAL_TRIALS research · 2015-05-12
  Clinical Trial Update: An Exercise Intervention for Breast Cancer Patients: Feasibility and Effectiveness (BEAT Cancer Trial; Pilot Study) [Phase 1]

  The BEAT Cancer Trial is a Phase 1 pilot study evaluating the feasibility and effectiveness of an exercise intervention for breast cancer pa…

• CLINICAL_TRIALS research · 2015-05-12
  Clinical Trial Update: Patient Derived Breast Cancer Xenografts

  A clinical trial involving patient-derived xenografts for metastatic breast cancer conducted by Dartmouth-Hitchcock Medical Center has been …

• FDA approval · 2015-05-08
  FDA Approved: LEUPROLIDE ACETATE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)

  FDA approved a supplemental application for Leuprolide acetate submitted by Sun Pharmaceutical Industries, Inc.

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• CLINICAL_TRIALS research · 2015-05-08
  Clinical Trial Update: Identification of Genes That Predict Local Recurrence in Samples From Patients With Breast Cancer Treated on NSABP-B-28

  This clinical trial update describes research aimed at identifying gene expression signatures that predict local recurrence in breast cancer…

• CLINICAL_TRIALS trial_result · 2015-05-08
  Clinical Trial Update: An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)

  This completed observational pilot trial evaluated the feasibility of conducting genome-wide association studies using subject-provided info…

• CLINICAL_TRIALS research · 2015-05-08
  Clinical Trial Update: Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2

  This update describes a study collecting blood samples from high-risk postmenopausal women who participated in the breast cancer prevention …

• CLINICAL_TRIALS research · 2015-05-08
  Clinical Trial Update: Cancer Stem Cell Biomarkers as a Predictor of Response to Trastuzumab in Samples From Patients With Breast Cancer Previously Treated in the NSABP-B-31 Trial

  This clinical trial investigates cancer stem cell biomarkers as predictors of response to trastuzumab in breast cancer patients who were pre…

• CLINICAL_TRIALS trial_result · 2015-05-07
  Clinical Trial Update: Cisplatin and Paclitaxel With or Without Everolimus in Treating Patients With Stage II or Stage III Breast Cancer [Phase 2]

  This Phase 2 trial evaluated adding everolimus to cisplatin and paclitaxel for stage II/III breast cancer. The study has completed, and resu…

• CLINICAL_TRIALS trial_result · 2015-05-06
  Clinical Trial Update: Inflammatory Response and Tissue Fibrosis/ Lymphatico-venous Bypass

  A completed clinical trial update from MD Anderson assessing inflammatory response and tissue fibrosis related to lymphatico-venous bypass a…

• CLINICAL_TRIALS withdrawal · 2015-05-05
  Clinical Trial Update: Combination Chemotherapy Plus Biological Therapy in Treating Patients With Stage II or Stage III Breast Cancer [Phase 1, Phase 2]

  This clinical trial evaluating combination chemotherapy plus biological therapy for stage II or stage III breast cancer has been withdrawn.

• CLINICAL_TRIALS trial_result · 2015-05-04
  Clinical Trial Update: Neoadjuvant Tipifarnib, Docetaxel, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIA or Stage IIIB Breast Cancer [Phase 1, Phase 2]

  Phase 1/2 clinical trial evaluating neoadjuvant tipifarnib with docetaxel and capecitabine in adults with locally advanced or metastatic bre…

• CLINICAL_TRIALS withdrawal · 2015-05-04
  Clinical Trial Update: Phase 2 Trial Of CP-751,871 And Docetaxel In Advanced Breast Cancer [Phase 2]

  Pfizer-sponsored Phase 2 trial of CP-751,871 in combination with docetaxel for advanced breast cancer has been withdrawn.

• CLINICAL_TRIALS withdrawal · 2015-05-04
  Clinical Trial Update: A Study Of Docetaxel Or Docetaxel Plus PF-3512676 To Treat Patients With Advanced Breast Cancer. [Phase 2]

  A Phase 2 trial comparing docetaxel alone versus docetaxel plus PF-3512676 for advanced breast cancer was withdrawn.

• CLINICAL_TRIALS trial_result · 2015-05-01
  Clinical Trial Update: Safety and Efficacy Study of the Trifunctional Antibody Ertumaxomab to Treat Patients With Advanced or Metastatic Breast Cancer [Phase 2]

  Phase 2 safety and efficacy study of Ertumaxomab in patients with advanced or metastatic breast cancer was terminated.

• CLINICAL_TRIALS trial_result · 2015-05-01
  Clinical Trial Update: Breast Cancer Survivorship & Work-Related Cognitive Limitation

  Status update for a completed clinical trial evaluating work-related cognitive limitations in breast cancer survivors.

• CLINICAL_TRIALS trial_result · 2015-04-30
  Clinical Trial Update: Radiolabeled Monoclonal Antibody Followed by Peripheral Stem Cell Transplantation in Treating Patients With Relapsed or Metastatic Breast Cancer [Phase 1]

  A Phase 1 clinical trial evaluated a radiolabeled monoclonal antibody followed by peripheral stem cell transplantation in patients with rela…

• CLINICAL_TRIALS trial_result · 2015-04-30
  Clinical Trial Update: Hospital Based Group Intervention for Breast Cancer Patients. [NA]

  A hospital-based group intervention for breast cancer patients has completed, assessing effects on anxiety, depression, quality of life, and…

• CLINICAL_TRIALS trial_result · 2015-04-29
  Clinical Trial Update: Adjuvant Oophorectomy and Tamoxifen in Premenopausal Women With Hormone Receptor-Positive Breast Cancer [Phase 3]

  A Phase 3 clinical trial evaluating adjuvant oophorectomy plus tamoxifen in premenopausal women with hormone receptor-positive breast cancer…

• CLINICAL_TRIALS trial_result · 2015-04-29
  Clinical Trial Update: LMB-9 Immunotoxin in Treating Patients With Advanced Solid Tumors [Phase 1]

  Phase 1 trial update on LMB-9 immunotoxin in patients with advanced solid tumors. The study has completed and includes bladder cancer, breas…

• CLINICAL_TRIALS trial_result · 2015-04-28
  Clinical Trial Update: Cellular Adoptive Immunotherapy in Treating a Patient Who Has Undergone a Donor Stem Cell Transplant for Breast Cancer That Has Spread to the Lung [Phase 1]

  A phase 1 trial sponsored by the National Cancer Institute reports on cellular adoptive immunotherapy for a patient with metastatic breast c…

• CLINICAL_TRIALS withdrawal · 2015-04-27
  Clinical Trial Update: LDE225 in Treating Patients With Stage II-III Estrogen Receptor- and HER2-Negative Breast Cancer [Phase 2]

  Phase 2 trial evaluating LDE225 (sonidegib) for stage II-III estrogen receptor- and HER2-negative breast cancer has been withdrawn.

• CLINICAL_TRIALS trial_result · 2015-04-24
  Clinical Trial Update: Comparing the Efficacy and Tolerability of Fulvestrant 500 mg Versus 250 mg in Advanced Breast Cancer Women [Phase 3]

  A Phase 3 trial in women with breast cancer compared fulvestrant 500 mg versus 250 mg; results were posted in 2015.

• FDA approval · 2015-04-22
  FDA Approved: SOLTAMOX — Supplemental Application (Mayne Pharma)

  The FDA approved a supplemental application for Soltamox (tamoxifen citrate) filed by Mayne Pharma.