Breast Cancer

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases [Phase 2]

  Phase 2 clinical trial evaluating multi-mode thermal therapy in combination with immunotherapy for HER2-negative breast cancer with liver me…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002) [Phase 1]

  Phase 1 clinical trial MK-7119-002 assesses safety and pharmacokinetics of tucatinib (MK-7119) in Chinese participants with cancer; the stud…

• CLINICAL_TRIALS trial_result · 2026-03-12
  Clinical Trial Update: A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer [NA]

  A pilot clinical trial is evaluating focused massage to reduce pain, improve mobility, and enhance quality of life for breast cancer patient…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors [Phase 1, Phase 2]

  A Mayo Clinic-sponsored phase 1/2 trial evaluating a personalized neoantigen peptide-based vaccine in combination with pembrolizumab for adv…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: SAHARA-04 : Adaptive Radiotherapy in Hypersensitive Patients and High Locoregional Risk Breast Cancer With ETHOS Technology [NA]

  SAHARA-04 is a trial evaluating adaptive radiotherapy using ETHOS technology for hypersensitive patients with high locoregional risk breast …

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• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Personalization of Breast Radiotherapy According to Loco-regional Recurrence Risk and Toxicity Probability [NA]

  A recruiting clinical trial investigating personalization of breast radiotherapy based on loco-regional recurrence risk and predicted toxici…

• CLINICAL_TRIALS trial_result · 2026-03-12
  Clinical Trial Update: HER2-low Unresectable and/or Metastatic Breast Cancer in Russia

  A clinical trial update indicates a study evaluating a therapy for HER2-low unresectable and/or metastatic breast cancer in Russia has compl…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors [Phase 1]

  Phase 1 study evaluating NKT5097 in adults with advanced or metastatic solid tumors, including various breast cancer subtypes and gynecologi…

• CLINICAL_TRIALS trial_result · 2026-03-12
  Clinical Trial Update: Study of Vitamin D Supplementation Tailored to Vitamin D Deficiency in Breast Cancer Patients [Phase 3]

  A Phase 3 trial evaluating tailored vitamin D supplementation for vitamin D-deficient breast cancer patients has completed.

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer [Phase 2]

  A Phase 2 neoadjuvant study to evaluate Zanidatamab in combination with chemotherapy for HER2-positive breast cancer is currently recruiting…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease [Phase 2]

  This update notes a Phase 2 trial evaluating HER3-DXd in metastatic breast cancer and advanced non-small cell lung cancer (including brain m…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer [Phase 2]

  This document describes a Phase 2 trial evaluating serplulimab in combination with SHR-A1811 as neoadjuvant therapy for triple-negative brea…

• CLINICAL_TRIALS trial_result · 2026-03-12
  Clinical Trial Update: Exploratory Study Therapeutic Fasting Reduce Physical Limitations, Quality of Life During Aromatase Inhibitor Therapy [NA]

  This update describes an exploratory study evaluating whether therapeutic fasting can reduce physical limitations and improve quality of lif…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Impact of Supplementation With Synbiotics and Prebiotics on Cognitive Decline Associated With Neoadjuvant Chemotherapy in First-line Patients With Breast Cancer [NA]

  A clinical trial is evaluating whether synbiotics and prebiotics can lessen chemotherapy-associated cognitive decline (chemobrain) in first-…

• CLINICAL_TRIALS other · 2026-03-12
  Clinical Trial Update: Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer [Phase 1]

  Phase 1 clinical trial evaluating a personalized neo-antigen peptide vaccine for advanced cancers (metastatic breast cancer, melanoma, and n…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Evaluation of Clinical Efficacy of Augmented Reality (AR)-Based Breast Cancer Medical Imaging Solution (SKIA-Breast) Localization Method in Breast Cancer Patients [NA]

  A clinical trial is evaluating the clinical efficacy of an augmented reality–based breast cancer localization method (SKIA-Breast) in breast…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Feasibility of Serial Multisite Image-guided Biopsy to Study Breast Cancer Evolution

  This clinical trial update describes a feasibility study using serial image-guided biopsies across multiple sites to study how breast cancer…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Facility-Based Multi-Modal Rehab vs. Home-Based Resistance Exercise for Quality of Life in Breast Cancer Survivors [NA]

  This clinical trial compares facility-based multi-modal rehabilitation to home-based resistance exercise to improve quality of life in breas…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission [Phase 2]

  This Phase 2 trial update describes the ctDNA-guided adaptive study 'HERizon-Breast' evaluating sequential anti-HER2 therapies with CNS prop…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Investigation of the Effectiveness of Progressive Resistance Exercise Training in the Management of Lymphedema. [NA]

  This document describes a clinical trial evaluating progressive resistance exercise training for the management of lymphedema, including pat…

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: Large Language Model-Based Emotional Management for Breast Cancer Patients [NA]

  This clinical trial investigates a large language model-based emotional management intervention for patients with primary breast cancer and …

• CLINICAL_TRIALS research · 2026-03-12
  Clinical Trial Update: A Validation Study to Determine Concordance of Liquid Biopsy and Breast Cancer Diagnosis

  A clinical trial update for a validation study aiming to determine how well liquid biopsy results concord with breast cancer diagnosis; the …

• CLINICAL_TRIALS trial_result · 2026-03-11
  Clinical Trial Update: Letrozole Plus Ribociclib or Placebo as Neo-adjuvant Therapy in ER-positive, HER2-negative Early Breast Cancer [Phase 2]

  Phase 2 trial update evaluating letrozole plus ribociclib versus letrozole plus placebo as neoadjuvant therapy for ER-positive, HER2-negativ…

• CLINICAL_TRIALS research · 2026-03-11
  Clinical Trial Update: Emulation of the MONALEESA-2 Trial Using Specialty Oncology Electronic Health Records Databases

  A real-world evidence study documenting an emulation of the MONALEESA-2 trial using specialty oncology electronic health records to evaluate…

• CLINICAL_TRIALS research · 2026-03-11
  Clinical Trial Update: Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49) [Phase 3]

  This is a Phase 3 clinical trial update for pembrolizumab plus chemotherapy versus placebo plus chemotherapy in HR+/HER2- locally recurrent …