Breast Cancer
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CLINICAL_TRIALS research · 2016-10-25Clinical Trial Update: Age-related Changes in the Immune System and Their Impact on Elderly Breast Cancer
This clinical trial update examines how age-related changes in the immune system may affect outcomes in elderly patients with breast cancer.…
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer [Phase 2]
This update reports results from a Phase 2 dose-finding trial of Empegfilgrastim for preventing chemotherapy-induced neutropenia in breast c…
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Study of the Efficacy and Safety of Empegfilgrastim for Neutropenia Prophylaxis in Breast Cancer Patients [Phase 3]
Phase 3 study assessing Empegfilgrastim for neutropenia prophylaxis in breast cancer patients undergoing chemotherapy; results were posted i…
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: A Safety and Efficacy Study of BCD-022 With Paclitaxel Compared to Herceptin With Paclitaxel in HER2+ Metastatic Breast Cancer Patients [Phase 3]
Phase 3 trial comparing BCD-022 with paclitaxel to Herceptin with paclitaxel in HER2-positive metastatic breast cancer has completed with re…
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CLINICAL_TRIALS research · 2016-10-24Clinical Trial Update: Preoperative Imaging in DIEP Flap Breast Reconstruction [NA]
This clinical trial update discusses ongoing evaluation of preoperative imaging for DIEP flap breast reconstruction in breast cancer patient…
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CLINICAL_TRIALS withdrawal · 2016-10-21Clinical Trial Update: Treatment of Benign Breast Deformities and Post-Segmental Mastectomy Breast Deformities With Autologous Fat Grafting (AFT) [NA]
A University of Pittsburgh trial evaluating autologous fat grafting to treat benign breast deformities and deformities after segmental maste…
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Evaluate the Safety Profile and Ability of TW1025 Oral Solution to Decrease Fatigue [Phase 2]
A Phase 2 trial evaluating TW1025 oral solution for safety and reduction of fatigue in patients with metastatic breast cancer was terminated…
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CLINICAL_TRIALS research · 2016-10-21Clinical Trial Update: Is Any Additional Information Gained Regarding Margins Using 3D Tomosynthesis Vs 2D Conventional Digital Imaging When Imaging Operative Breast Specimens? [NA]
Clinical trial update examining whether 3D tomosynthesis provides additional information for margins over 2D imaging when assessing operativ…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Efficacy and Safety of Dignicap System for Preventing Chemotherapy Induced Alopecia [NA]
Update on a clinical trial evaluating the efficacy and safety of the DigniCap scalp cooling system to prevent chemotherapy-induced hair loss…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: Leuplin SR 11.25 mg Injection Kit Specified Drug-use Survey: "QOL Survey in Premenopausal Breast Cancer Patients"
Completed clinical trial update presenting results from a quality-of-life survey in premenopausal breast cancer patients treated with Leupli…
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CLINICAL_TRIALS research · 2016-10-18Clinical Trial Update: Study of Preoperative Chemotherapy for Early Triple Negative or HER2-positive Operable Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating preoperative chemotherapy for patients with early triple-negative breast cancer or HER2-positive operable …
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Relational and Emotional Mechanisms of a Supportive-expressive Group Intervention in Breast Cancer [NA]
This clinical trial update describes a study evaluating the relational and emotional mechanisms of a supportive-expressive group interventio…
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CLINICAL_TRIALS other · 2016-10-14Clinical Trial Update: Personalised Program for Women Treated for Hodgkin Disease [NA]
This clinical trial update notes termination of a personalized program study for women treated for Hodgkin lymphoma, including participants …
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CLINICAL_TRIALS trial_result · 2016-10-14Clinical Trial Update: Safety Study of Human MUC-1 (Mucin-1) Adenoviral Vector Vaccine for Immunotherapy of Epithelial Cancers [Phase 1]
This entry covers a Phase 1 safety study of a human MUC-1 adenoviral vector vaccine designed for immunotherapy of epithelial cancers. The st…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA) [Phase 3]
PHEREXA trial evaluated trastuzumab and capecitabine with or without pertuzumab in HER2-positive metastatic breast cancer; results completed…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: microRNA of Human Epidermal Growth Factor Receptor 2 （HER2）Positive Patient Treated With Herceptin
An update on a HER2-positive breast cancer patient treated with Herceptin (trastuzumab), focusing on microRNA findings related to the case.
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CLINICAL_TRIALS withdrawal · 2016-10-13Clinical Trial Update: Safety and Efficacy of Sentinel Node Biopsy Omission for Breast Cancer Patients Who Plan to Have Adjuvant Chemotherapy [Phase 2]
A Phase 2 trial evaluating the omission of sentinel node biopsy in breast cancer patients planning adjuvant chemotherapy has been withdrawn.…
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FDA approval · 2016-10-12FDA Approved: ZORTRESS — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for ZORTRESS (everolimus) submitted by Novartis Pharmaceuticals Corporation. The action likely a…
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Phase II Pilot Study Assessing Efficacy of a Cisplatin - Métronomic Cyclophosphamide Treatment in Patients With Stade IV Triple Negative Breast Cancer Secondary Resistant to Anthracyclines and Taxanes [Phase 2]
Phase II pilot study evaluating cisplatin with metronomic cyclophosphamide in metastatic, stage IV triple-negative breast cancer resistant t…
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CLINICAL_TRIALS trial_result · 2016-10-10Clinical Trial Update: Phase I, Dose Study to Look at the Safety and Pharmacokinetics of AZD8835 in Patients With Advanced Solid Tumours [Phase 1]
Phase I dose-escalation study of AZD8835 to assess safety and pharmacokinetics in patients with advanced solid tumors, including breast canc…
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: Eribulin Mesylate Phase IV Clinical Trial in Korean Patients With Metastatic or Locally Advanced Breast Cancer [Phase 4]
Phase IV clinical trial results for eribulin mesylate in Korean patients with metastatic or locally advanced breast cancer have been posted.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating an NY-ESO-1 vaccine therapy with or without sirolimus in patients whose tumors express NY-ESO-1.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: A Prospective Comparative Study Between Oncoplastic Breast Surgery and Standard Wide Local Excision [NA]
A completed prospective trial comparing oncoplastic breast surgery with standard wide local excision for breast cancer.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Study of the Outcomes of Intraoperative Margin Assessment With MarginProbe [NA]
This document reports the completion of a clinical trial evaluating intraoperative margin assessment with MarginProbe in breast cancer.
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CLINICAL_TRIALS research · 2016-10-03Clinical Trial Update: Pre-pectoral Breast Reconstruction PART 2 [Phase 3]
This document reports a Phase 3 clinical trial update for pre-pectoral breast reconstruction in patients with breast cancer.