Breast Cancer
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Analysis of Initial Adherence and Its Impact on Long-term Adherence to Hormonal Therapy for Breast Cancer [NA]
A clinical trial update analyzing how initial adherence to hormonal therapy in breast cancer influences long-term adherence.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: FDG PET and DCE-MRI in Predicting Response to Treatment in Patients With Breast Cancer [NA]
Clinical trial investigating FDG PET and DCE-MRI to predict treatment response in breast cancer patients has been terminated with posted res…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Aquatic Exercise Study for Breast Cancer Patients With Lymphedema [NA]
This entry notes that the aquatic exercise study for breast cancer patients with lymphedema has completed. The sponsor is Baylor Research In…
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EMA safety_alert · 2017-06-09PRAC concludes there is no evidence of a change in known risk of neutropenic enterocolitis with docetaxel
The EMA's Pharmacovigilance Risk Assessment Committee (PRAC) concluded there is no evidence of a change in the known risk of neutropenic ent…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: A Study Evaluating Trastuzumab Emtansine Plus Pertuzumab Compared With Chemotherapy Plus Trastuzumab and Pertuzumab for Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer [Phase 3]
Phase 3 trial comparing trastuzumab emtansine plus pertuzumab against chemotherapy plus trastuzumab and pertuzumab in HER2-positive breast c…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Radiation Therapy in Treating Women With Locally Recurrent Breast Cancer Previously Treated With Repeat Breast-Preserving Surgery [Phase 2]
Phase 2 clinical trial assessing radiation therapy for women with locally recurrent breast cancer after repeat breast-preserving surgery; st…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Efficacy of Enhanced Recovery After Surgery Pathway for Total Mastectomy
A completed trial assesses the efficacy of an Enhanced Recovery After Surgery pathway for total mastectomy in female breast cancer patients.
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer [Phase 2]
Phase 2 trial evaluating tangential radiation therapy without axillary dissection in early-stage breast cancer has completed. This is a Clin…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Axillary Lymph Node Preservation Surgery in Reducing Lymphedema in Patients With Breast Cancer [Phase 1, Phase 2]
A Phase 1/2 trial evaluating axillary lymph node preservation surgery to reduce lymphedema in breast cancer patients was terminated, with re…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: A Study of Pertuzumab in Combination With Trastuzumab Plus an Aromatase Inhibitor in Participants With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive and Hormone Receptor-Positive Advanced Breast Cancer [Phase 2]
Phase 2 trial assessing pertuzumab with trastuzumab and an aromatase inhibitor in metastatic HER2-positive, hormone receptor-positive advanc…
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CLINICAL_TRIALS withdrawal · 2017-06-07Clinical Trial Update: Lapatinib or Trastuzumab Given Prior to Surgery With Chemotherapy in Patients With Early Breast Cancer [Phase 2]
A Phase 2 clinical trial evaluating lapatinib or trastuzumab before surgery with chemotherapy in patients with early breast cancer has been …
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR [NA]
A completed clinical trial investigates improving adherence to oral cancer agents and self-care of symptoms using an IVR system, sponsored b…
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CLINICAL_TRIALS research · 2017-06-07Clinical Trial Update: Evaluation of Thyroid Abnormity Incidence and Thyroid Toxicity During Chemotherapy Among Newly Diagnosed Breast Cancer
A clinical trial update evaluating the incidence of thyroid abnormalities and thyroid toxicity during chemotherapy in newly diagnosed breast…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Hormone Therapy and Combination Chemotherapy Before and After Surgery in Treating Patients With Stage I-IIIA Breast Cancer [Phase 2]
Phase 2 trial of hormone therapy and combination chemotherapy before and after surgery for stage I-IIIA breast cancer was terminated; result…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Taxotere and Adriamycin/Cytoxan (AC) Validation in Breast Cancer Patients [Phase 2]
Phase 2 clinical trial update evaluating Taxotere with Adriamycin/Cytoxan (AC) in breast cancer patients; study completed with results poste…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients [EARLY_Phase 1]
A Phase 1 feasibility study evaluating a quitline-based smoking cessation intervention in cancer patients completed with results posted in 2…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Navelbine, Taxol, Herceptin and Neupogen in Stage IV Breast Cancer: A Phase I - II Trial [Phase 1, Phase 2]
A Phase I–II trial evaluating a four-drug combination of vinorelbine, paclitaxel, trastuzumab, and filgrastim for stage IV breast cancer; th…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing Surgery [Phase 2]
A Phase 2 trial evaluating radiation therapy in postmenopausal women with early-stage breast cancer undergoing surgery was terminated; resul…
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CLINICAL_TRIALS research · 2017-06-06Clinical Trial Update: Orall Administered Probiotics to Improve the Quality of the Vaginal Flora of Women With Breast Cancer and Chemotherapy. [NA]
A clinical trial evaluated orally administered probiotics to improve vaginal flora in women with breast cancer undergoing chemotherapy. The …
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CLINICAL_TRIALS withdrawal · 2017-06-05Clinical Trial Update: Dose Optimization of Rosuvastatin in Early Stage and Metastatic Estrogen Receptor Positive Breast Cancer Patients on Endocrine Therapy [Phase 1]
A Phase 1 trial investigating rosuvastatin for dose optimization in early-stage and metastatic estrogen receptor-positive breast cancer pati…
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CLINICAL_TRIALS other · 2017-06-05Clinical Trial Update: 3DCRT vs. IMRT in Early Breast Cancer [Phase 3]
A Phase 3 trial comparing 3D conformal radiotherapy (3DCRT) with intensity-modulated radiotherapy (IMRT) in early breast cancer, focusing on…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response [Phase 2]
This update reports Phase 2 results from a trial of platinum-based chemotherapy in triple-negative metastatic breast cancer and evaluates p6…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: The Efficacy and Safety of PEG-rhG-CSF in Preventing Chemotherapy-induced Neutropenia [Phase 3]
Phase 3 trial evaluating the efficacy and safety of PEG-rhG-CSF to prevent chemotherapy-induced neutropenia in breast cancer patients.
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CLINICAL_TRIALS research · 2017-06-01Clinical Trial Update: PCI in Advanced Triple Negative Breast Cancer Patients Who Response to 1st Line Chemotherapy [NA]
This document provides a clinical trial update on the use of prophylactic cranial irradiation in advanced triple-negative breast cancer pati…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: A Study of Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041 AM3) [Phase 2]
Phase 2 study evaluating ridaforolimus in combination with dalotuzumab versus standard of care in estrogen receptor-positive breast cancer h…